COMSAE Phase 1 Form 113 Exam
Questions And Correct Answers (Verified
Answers) Plus Rationales
1. A 32-year-old man presents with acute right flank pain radiating to
the groin. Urinalysis shows microscopic hematuria. What is the most
likely diagnosis?
A. Acute cholecystitis
B. Appendicitis
C. Nephrolithiasis
D. Pyelonephritis
Nephrolithiasis causes sudden flank pain radiating to the groin with
hematuria.
2. A 27-year-old woman presents with fatigue and pallor. Labs reveal
low hemoglobin and low MCV. Which is the most likely cause?
A. Vitamin B12 deficiency
B. Iron deficiency
C. Aplastic anemia
D. Sickle cell disease
Iron deficiency is the most common cause of microcytic anemia.
,3. A 45-year-old man with a history of alcoholism develops confusion,
ophthalmoplegia, and ataxia. Diagnosis?
A. Korsakoff syndrome
B. Wernicke encephalopathy
C. Delirium tremens
D. Hepatic encephalopathy
The triad of confusion, ophthalmoplegia, ataxia indicates thiamine
deficiency → Wernicke.
4. A 63-year-old woman presents with progressive dyspnea.
Pulmonary function tests show decreased FEV1/FVC ratio. Likely
diagnosis?
A. Restrictive lung disease
B. Obstructive lung disease
C. Pulmonary hypertension
D. Pleural effusion
FEV1/FVC < 70% indicates obstruction.
5. A newborn presents with a continuous "machine-like" murmur.
Diagnosis?
A. VSD
B. PDA
C. ASD
,D. Tetralogy of Fallot
PDA produces continuous murmur.
6. A 29-year-old woman has exophthalmos, heat intolerance, and low
TSH. Which is most likely?
A. Hashimoto thyroiditis
B. Graves disease
C. Subacute thyroiditis
D. Iodine deficiency
Hyperthyroidism with exophthalmos is Graves.
7. A 55-year-old man has chest pain relieved by nitroglycerin. What is
the likely pathology?
A. Plaque rupture
B. Stable angina
C. Aortic dissection
D. Prinzmetal angina
Stable angina is exertional and relieved by rest/nitro.
8. A patient has jaundice, pruritus, and elevated conjugated bilirubin.
What is the likely cause?
A. Hemolysis
B. Obstructive cholestasis
C. Gilbert syndrome
, D. Crigler-Najjar
Conjugated bilirubin + pruritus suggests obstruction.
9. A 7-year-old presents with a "slapped cheek" rash. What virus is
responsible?
A. HSV
B. Coxsackie A
C. Parvovirus B19
D. EBV
Parvovirus causes erythema infectiosum.
10. A 4-year-old boy with recurrent infections has absent thymic
shadow. Diagnosis?
A. Bruton's agammaglobulinemia
B. DiGeorge syndrome
C. SCID
D. Hyper IgE syndrome
DiGeorge = thymic aplasia.
11. A 46-year-old man has elevated AST/ALT, gynecomastia, testicular
atrophy, and tremor. Diagnosis?
A. Alcoholic hepatitis
B. Cirrhosis
C. Hemochromatosis
Questions And Correct Answers (Verified
Answers) Plus Rationales
1. A 32-year-old man presents with acute right flank pain radiating to
the groin. Urinalysis shows microscopic hematuria. What is the most
likely diagnosis?
A. Acute cholecystitis
B. Appendicitis
C. Nephrolithiasis
D. Pyelonephritis
Nephrolithiasis causes sudden flank pain radiating to the groin with
hematuria.
2. A 27-year-old woman presents with fatigue and pallor. Labs reveal
low hemoglobin and low MCV. Which is the most likely cause?
A. Vitamin B12 deficiency
B. Iron deficiency
C. Aplastic anemia
D. Sickle cell disease
Iron deficiency is the most common cause of microcytic anemia.
,3. A 45-year-old man with a history of alcoholism develops confusion,
ophthalmoplegia, and ataxia. Diagnosis?
A. Korsakoff syndrome
B. Wernicke encephalopathy
C. Delirium tremens
D. Hepatic encephalopathy
The triad of confusion, ophthalmoplegia, ataxia indicates thiamine
deficiency → Wernicke.
4. A 63-year-old woman presents with progressive dyspnea.
Pulmonary function tests show decreased FEV1/FVC ratio. Likely
diagnosis?
A. Restrictive lung disease
B. Obstructive lung disease
C. Pulmonary hypertension
D. Pleural effusion
FEV1/FVC < 70% indicates obstruction.
5. A newborn presents with a continuous "machine-like" murmur.
Diagnosis?
A. VSD
B. PDA
C. ASD
,D. Tetralogy of Fallot
PDA produces continuous murmur.
6. A 29-year-old woman has exophthalmos, heat intolerance, and low
TSH. Which is most likely?
A. Hashimoto thyroiditis
B. Graves disease
C. Subacute thyroiditis
D. Iodine deficiency
Hyperthyroidism with exophthalmos is Graves.
7. A 55-year-old man has chest pain relieved by nitroglycerin. What is
the likely pathology?
A. Plaque rupture
B. Stable angina
C. Aortic dissection
D. Prinzmetal angina
Stable angina is exertional and relieved by rest/nitro.
8. A patient has jaundice, pruritus, and elevated conjugated bilirubin.
What is the likely cause?
A. Hemolysis
B. Obstructive cholestasis
C. Gilbert syndrome
, D. Crigler-Najjar
Conjugated bilirubin + pruritus suggests obstruction.
9. A 7-year-old presents with a "slapped cheek" rash. What virus is
responsible?
A. HSV
B. Coxsackie A
C. Parvovirus B19
D. EBV
Parvovirus causes erythema infectiosum.
10. A 4-year-old boy with recurrent infections has absent thymic
shadow. Diagnosis?
A. Bruton's agammaglobulinemia
B. DiGeorge syndrome
C. SCID
D. Hyper IgE syndrome
DiGeorge = thymic aplasia.
11. A 46-year-old man has elevated AST/ALT, gynecomastia, testicular
atrophy, and tremor. Diagnosis?
A. Alcoholic hepatitis
B. Cirrhosis
C. Hemochromatosis
