COMSAE PHASE 1 FORM 113 EXAMINATION QUESTIONS
AND CORRECT ANSWER WITH EXPLANATION STUDY
GUIDE FOR OSTEOPATHIC MEDICAL STUDENT
1.
A patient with crushing chest pain radiating to the jaw most likely has:
A. GERD
B. Myocardial infarction
C. Asthma
D. Gastritis
Answer: B
Rationale: Radiating chest pain is classic for myocardial infarction.
2.
The most common cause of primary hypothyroidism is:
A. Graves disease
B. Hashimoto thyroiditis
C. Pituitary adenoma
D. Thyroid carcinoma
Answer: B
Rationale: Autoimmune thyroid destruction is the leading cause.
3.
Parkinson disease results primarily from deficiency of:
A. Serotonin
B. Dopamine
C. Histamine
D. Acetylcholine
Answer: B
Rationale: Degeneration of dopaminergic neurons causes symptoms.
,4.
The most common cause of urinary tract infection is:
A. Pseudomonas aeruginosa
B. Escherichia coli
C. Staphylococcus aureus
D. Streptococcus pneumoniae
Answer: B
Rationale: E. coli causes most UTIs.
5.
Hyperglycemia, ketones, and metabolic acidosis suggest:
A. Hypoglycemia
B. Diabetic ketoacidosis
C. SIADH
D. Hyperosmolar syndrome
Answer: B
Rationale: DKA presents with ketosis and acidosis.
6.
The antidote for opioid overdose is:
A. Flumazenil
B. Naloxone
C. Atropine
D. Epinephrine
Answer: B
Rationale: Naloxone reverses opioid toxicity.
7.
The cardiac valve most commonly affected in rheumatic fever is:
A. Pulmonary valve
B. Mitral valve
C. Tricuspid valve
D. Aortic valve
, Answer: B
Rationale: Rheumatic disease commonly damages the mitral valve.
8.
A “boot-shaped” heart on chest X-ray indicates:
A. Atrial septal defect
B. Tetralogy of Fallot
C. Ventricular septal defect
D. Coarctation of the aorta
Answer: B
Rationale: Right ventricular hypertrophy causes the appearance.
9.
The leading cause of COPD is:
A. Viral infection
B. Smoking
C. Tuberculosis
D. Asthma
Answer: B
Rationale: Cigarette smoking damages the lungs.
10.
Elevated TSH with low T4 indicates:
A. Hyperthyroidism
B. Primary hypothyroidism
C. Secondary hypothyroidism
D. Euthyroid syndrome
Answer: B
Rationale: Thyroid gland failure increases TSH.
11.
AND CORRECT ANSWER WITH EXPLANATION STUDY
GUIDE FOR OSTEOPATHIC MEDICAL STUDENT
1.
A patient with crushing chest pain radiating to the jaw most likely has:
A. GERD
B. Myocardial infarction
C. Asthma
D. Gastritis
Answer: B
Rationale: Radiating chest pain is classic for myocardial infarction.
2.
The most common cause of primary hypothyroidism is:
A. Graves disease
B. Hashimoto thyroiditis
C. Pituitary adenoma
D. Thyroid carcinoma
Answer: B
Rationale: Autoimmune thyroid destruction is the leading cause.
3.
Parkinson disease results primarily from deficiency of:
A. Serotonin
B. Dopamine
C. Histamine
D. Acetylcholine
Answer: B
Rationale: Degeneration of dopaminergic neurons causes symptoms.
,4.
The most common cause of urinary tract infection is:
A. Pseudomonas aeruginosa
B. Escherichia coli
C. Staphylococcus aureus
D. Streptococcus pneumoniae
Answer: B
Rationale: E. coli causes most UTIs.
5.
Hyperglycemia, ketones, and metabolic acidosis suggest:
A. Hypoglycemia
B. Diabetic ketoacidosis
C. SIADH
D. Hyperosmolar syndrome
Answer: B
Rationale: DKA presents with ketosis and acidosis.
6.
The antidote for opioid overdose is:
A. Flumazenil
B. Naloxone
C. Atropine
D. Epinephrine
Answer: B
Rationale: Naloxone reverses opioid toxicity.
7.
The cardiac valve most commonly affected in rheumatic fever is:
A. Pulmonary valve
B. Mitral valve
C. Tricuspid valve
D. Aortic valve
, Answer: B
Rationale: Rheumatic disease commonly damages the mitral valve.
8.
A “boot-shaped” heart on chest X-ray indicates:
A. Atrial septal defect
B. Tetralogy of Fallot
C. Ventricular septal defect
D. Coarctation of the aorta
Answer: B
Rationale: Right ventricular hypertrophy causes the appearance.
9.
The leading cause of COPD is:
A. Viral infection
B. Smoking
C. Tuberculosis
D. Asthma
Answer: B
Rationale: Cigarette smoking damages the lungs.
10.
Elevated TSH with low T4 indicates:
A. Hyperthyroidism
B. Primary hypothyroidism
C. Secondary hypothyroidism
D. Euthyroid syndrome
Answer: B
Rationale: Thyroid gland failure increases TSH.
11.
