Page 1 of 162
COMSAE Phase 1 Form 113 exam COMPLETE QUESTIONS AND
DETAILED SOLUTIONS LATEST UPDATE THIS YEAR-JUST
RELEASED
COMSAE Phase 1 Form 113 —
Coverage
Osteopathic Principles & OMM: Viscerosomatic reflexes, autonomics, Chapman points,
counterstrain, muscle energy, HVLA, myofascial release, lymphatics, sacral/innominate
dysfunctions, Fryette mechanics, rib dysfunctions, cranial strain patterns.
Anatomy: Brachial plexus, dermatomes/myotomes, cranial nerves, spinal cord syndromes,
pelvic anatomy, abdominal blood supply, hernias, major joint injuries, coronary territories, GI
structural landmarks.
Physiology: Cardiac cycle/hemodynamics, Frank-Starling, respiratory mechanics, V/Q
concepts, renal filtration and clearance, RAAS, acid-base interpretation, endocrine feedback
loops, GI physiology, shock physiology.
, Page 2 of 162
Pathology: Cell injury, inflammation, granulomas, neoplasia genetics, thrombosis/embolism,
edema, autoimmune disease patterns, amyloidosis, major cardio/pulm/renal/hepatic pathology
syndromes.
Microbiology: Gram classification, toxins/virulence, respiratory/GI/STI/CNS organisms, HIV
opportunistic infections, fungi, parasites, viral replication patterns, hepatitis viruses, vaccines.
Immunology: Innate/adaptive immunity, T/B cell markers, MHC presentation, cytokines,
hypersensitivity reactions, immunodeficiencies, autoimmune mechanisms, transplant rejection,
complement deficiencies.
Pharmacology: Autonomics, cholinergic drugs, antibiotics MOA/toxicities, CV drugs, CNS
drugs, endocrine drugs, chemotherapy toxicities, CYP450 interactions, teratogenic medications.
Biochemistry & Genetics: Enzyme kinetics, metabolism pathways, vitamin deficiencies,
lysosomal storage diseases, inheritance patterns, genetic principles, heme synthesis disorders.
, Page 3 of 162
Neurology & Psychiatry: Stroke syndromes, spinal cord lesions, neurotransmitters,
seizures/drugs, movement disorders, demyelinating diseases, psychiatric disorders, substance
effects, defense mechanisms.
Cardiology: Murmurs, hypertension treatment, arrhythmias, heart failure, shock types,
endocarditis/rheumatic fever associations.
Pulmonary: Asthma vs COPD, PFT interpretation, PE vs pneumonia vs CHF, ARDS, pleural
effusions/pneumothorax, oxygen-hemoglobin curve shifts.
Renal & Electrolytes: AKI types, nephritic vs nephrotic syndromes, acid-base compensation,
SIADH vs DI, potassium disorders/ECG, diuretic mechanisms.
Endocrine & Reproductive: Diabetes, thyroid disorders, adrenal syndromes, MEN disorders,
pregnancy hormones, contraception pharmacology, gynecologic cancer screening basics.
GI & Hepatobiliary: Hepatitis serology, cirrhosis complications, pancreatitis, malabsorption
disorders, PUD/H. pylori, gallbladder and biliary infections.
, Page 4 of 162
Heme/Onc: Anemia classification, leukemia/lymphoma patterns, coagulation pathways, DIC
vs TTP vs HUS, platelet disorders, metastasis/paraneoplastic syndromes.
Musculoskeletal & Rheumatology: OA vs RA, gout vs pseudogout, lupus antibodies, vasculitis
syndromes, bone tumors, osteomyelitis organisms.
Biostatistics & Epidemiology: Sensitivity/specificity, PPV/NPV, likelihood ratios, study
designs, bias/confounding, RR vs OR, confidence intervals, screening principles.
Ethics & Medical Law: Ethical principles, informed consent/capacity, confidentiality
exceptions, surrogate decision hierarchy, professionalism/conflicts of interest, medical error
disclosure.
1.
A 24-year-old man develops wrist drop after falling asleep with his arm compressed over a
chair. Which nerve is most likely injured in this patient?
COMSAE Phase 1 Form 113 exam COMPLETE QUESTIONS AND
DETAILED SOLUTIONS LATEST UPDATE THIS YEAR-JUST
RELEASED
COMSAE Phase 1 Form 113 —
Coverage
Osteopathic Principles & OMM: Viscerosomatic reflexes, autonomics, Chapman points,
counterstrain, muscle energy, HVLA, myofascial release, lymphatics, sacral/innominate
dysfunctions, Fryette mechanics, rib dysfunctions, cranial strain patterns.
Anatomy: Brachial plexus, dermatomes/myotomes, cranial nerves, spinal cord syndromes,
pelvic anatomy, abdominal blood supply, hernias, major joint injuries, coronary territories, GI
structural landmarks.
Physiology: Cardiac cycle/hemodynamics, Frank-Starling, respiratory mechanics, V/Q
concepts, renal filtration and clearance, RAAS, acid-base interpretation, endocrine feedback
loops, GI physiology, shock physiology.
, Page 2 of 162
Pathology: Cell injury, inflammation, granulomas, neoplasia genetics, thrombosis/embolism,
edema, autoimmune disease patterns, amyloidosis, major cardio/pulm/renal/hepatic pathology
syndromes.
Microbiology: Gram classification, toxins/virulence, respiratory/GI/STI/CNS organisms, HIV
opportunistic infections, fungi, parasites, viral replication patterns, hepatitis viruses, vaccines.
Immunology: Innate/adaptive immunity, T/B cell markers, MHC presentation, cytokines,
hypersensitivity reactions, immunodeficiencies, autoimmune mechanisms, transplant rejection,
complement deficiencies.
Pharmacology: Autonomics, cholinergic drugs, antibiotics MOA/toxicities, CV drugs, CNS
drugs, endocrine drugs, chemotherapy toxicities, CYP450 interactions, teratogenic medications.
Biochemistry & Genetics: Enzyme kinetics, metabolism pathways, vitamin deficiencies,
lysosomal storage diseases, inheritance patterns, genetic principles, heme synthesis disorders.
, Page 3 of 162
Neurology & Psychiatry: Stroke syndromes, spinal cord lesions, neurotransmitters,
seizures/drugs, movement disorders, demyelinating diseases, psychiatric disorders, substance
effects, defense mechanisms.
Cardiology: Murmurs, hypertension treatment, arrhythmias, heart failure, shock types,
endocarditis/rheumatic fever associations.
Pulmonary: Asthma vs COPD, PFT interpretation, PE vs pneumonia vs CHF, ARDS, pleural
effusions/pneumothorax, oxygen-hemoglobin curve shifts.
Renal & Electrolytes: AKI types, nephritic vs nephrotic syndromes, acid-base compensation,
SIADH vs DI, potassium disorders/ECG, diuretic mechanisms.
Endocrine & Reproductive: Diabetes, thyroid disorders, adrenal syndromes, MEN disorders,
pregnancy hormones, contraception pharmacology, gynecologic cancer screening basics.
GI & Hepatobiliary: Hepatitis serology, cirrhosis complications, pancreatitis, malabsorption
disorders, PUD/H. pylori, gallbladder and biliary infections.
, Page 4 of 162
Heme/Onc: Anemia classification, leukemia/lymphoma patterns, coagulation pathways, DIC
vs TTP vs HUS, platelet disorders, metastasis/paraneoplastic syndromes.
Musculoskeletal & Rheumatology: OA vs RA, gout vs pseudogout, lupus antibodies, vasculitis
syndromes, bone tumors, osteomyelitis organisms.
Biostatistics & Epidemiology: Sensitivity/specificity, PPV/NPV, likelihood ratios, study
designs, bias/confounding, RR vs OR, confidence intervals, screening principles.
Ethics & Medical Law: Ethical principles, informed consent/capacity, confidentiality
exceptions, surrogate decision hierarchy, professionalism/conflicts of interest, medical error
disclosure.
1.
A 24-year-old man develops wrist drop after falling asleep with his arm compressed over a
chair. Which nerve is most likely injured in this patient?
