Patho I, Ch.43 - Structure and
Function of the Musculoskeletal
System Questions And Correct
Answers (Verified Answers) 2026
Which term is appropriate for the gelatinous material found in bone?
A. Collagen
B. Calcium
C. Protein
D. Ground substance - CORRECT ANSWER -D. Ground substance
Mature rigid bone is made up of rigid connective tissue consisting of cells, fibers, ground
substance, and minerals. The ground substance is the gelatinous material.
Which is the major remodeler cell of bone?
A. Osteoblast
B. Osteoid
C. Osteoclast
D. Osteocyte - CORRECT ANSWER -C. Osteoclast
Osteoclasts are considered the major remodeler cells of bone. Osteoid is nonmineralized bone
matrix. Osteoblasts are cells derived from mesenchymal stem cells that produce type I collagen.
An osteocyte is a transformed osteoblast that is trapped or surrounded in osteoid.
, Which are the most common mineral components of bone?
A. Magnesium and calcium
B. Phosphate and calcium
C. Phosphate and magnesium
D. Sodium and magnesium - CORRECT ANSWER -B. Phosphate and calcium
Phosphate and calcium form amorphous calcium phosphate compounds that are converted into
hydroxyapatite in the bone matrix.
What is the function of osteocalcin?
A. Forms compression-resistant networks between collagen fibrils.
B. Controls collagen interactions that lead to fibril formation.
C. Plays a part in bone resorption by recruiting osteoclasts.
D. Transports essential elements such as hormones. - CORRECT ANSWER -C. Plays a part in bone
resorption by recruiting osteoclasts.
Osteocalcin is a calcium-binding protein that preferentially binds to calcium that has already
crystallized. Osteocalcin plays a role in inhibiting calcium phosphate precipitation and in bone
resorption by recruiting osteoclasts. Proteoglycans are responsible for forming compression-
resistant networks between the collagen fibrils. Glycoproteins control the collagen interactions
that lead to fibril formation. Bone albumin is identical to serum albumin.
Which type of collagen is the glue that finally holds together the scaffolding of articular
cartilage?
A. II
Function of the Musculoskeletal
System Questions And Correct
Answers (Verified Answers) 2026
Which term is appropriate for the gelatinous material found in bone?
A. Collagen
B. Calcium
C. Protein
D. Ground substance - CORRECT ANSWER -D. Ground substance
Mature rigid bone is made up of rigid connective tissue consisting of cells, fibers, ground
substance, and minerals. The ground substance is the gelatinous material.
Which is the major remodeler cell of bone?
A. Osteoblast
B. Osteoid
C. Osteoclast
D. Osteocyte - CORRECT ANSWER -C. Osteoclast
Osteoclasts are considered the major remodeler cells of bone. Osteoid is nonmineralized bone
matrix. Osteoblasts are cells derived from mesenchymal stem cells that produce type I collagen.
An osteocyte is a transformed osteoblast that is trapped or surrounded in osteoid.
, Which are the most common mineral components of bone?
A. Magnesium and calcium
B. Phosphate and calcium
C. Phosphate and magnesium
D. Sodium and magnesium - CORRECT ANSWER -B. Phosphate and calcium
Phosphate and calcium form amorphous calcium phosphate compounds that are converted into
hydroxyapatite in the bone matrix.
What is the function of osteocalcin?
A. Forms compression-resistant networks between collagen fibrils.
B. Controls collagen interactions that lead to fibril formation.
C. Plays a part in bone resorption by recruiting osteoclasts.
D. Transports essential elements such as hormones. - CORRECT ANSWER -C. Plays a part in bone
resorption by recruiting osteoclasts.
Osteocalcin is a calcium-binding protein that preferentially binds to calcium that has already
crystallized. Osteocalcin plays a role in inhibiting calcium phosphate precipitation and in bone
resorption by recruiting osteoclasts. Proteoglycans are responsible for forming compression-
resistant networks between the collagen fibrils. Glycoproteins control the collagen interactions
that lead to fibril formation. Bone albumin is identical to serum albumin.
Which type of collagen is the glue that finally holds together the scaffolding of articular
cartilage?
A. II
