Nurs 615 Pharm Exam 1 – Maryville
Questions and 100% Correct Answers
How does hypoalbuminemia affect the process of prescribing?
Low albumin = more free drug (bc the drug can't bind to albumin aka protein) =
increased adverse effects
What is a Black Box Warning:
is considered a contraindication to administer that drug.
What is the drugs half-life?
Half-life specifically means the amount of time it takes for an administered drug to
be halfway cleared from the system.
Peak of action:
the time between drug administration and maximum concentration of drug in the
blood stream. Best therapeutic effect.
,Duration of action:
the time between onset of action and metabolism of drug below the minimum
needed for an effect. The length of time you have the drug in your system.
According to the WHO what is the first step in the prescribing process?
The first step is to define the patient's problem
The second step is to
specify the therapeutic objective
The third step is to
choose which drug or treatment is needed.
Step 4 of the WHO approach:
Start the treatment
Step 5 of the WHO approach:
,Educate the patient
Step 6 of the WHO approach:
Monitor the treatment
Phase 1 of drug development:
The drug is tested on healthy volunteers
Phase 2 of drug development:
trials with people who have the disease for which the drug is thought to be
effective
Phase 3 of drug development:
Large numbers of patients in medical research centers receive the drug in phase 3.
This larger sampling provides information about infrequent or rare adverse effects.
The FFA will approve a new drug application if phase 3 studies are satisfactory.
Phase 4 of drug development:
, This phase is voluntary and involves postmarket surveillance of the drug's
therapeutic effects at the completion of phase 3. The pharmaceutical company
receives reports from doctors and other health care professionals about the
therapeutic results and adverse effects of the drug. Some medications, for
example, have been found to be toxic and have been removed from the market
after their initial release.
Explain first pass metabolism
much of the drug is lost in the absorption process. The liver metabolizes many
drugs, thus reduces the bioavailability of the drug.
What is the fasted route of absorption:
The fastest route of absorption is inhalation, and not as mistakenly considered the
IV administration.
Why does the GI tract take longer to absorb?
The GI tract is lined with epithelial cells; drugs must permeate through these cells
in order to be absorbed into the circulatory system.
What is One particular cellular barrier that may prevent absorption of a given
drug?
Questions and 100% Correct Answers
How does hypoalbuminemia affect the process of prescribing?
Low albumin = more free drug (bc the drug can't bind to albumin aka protein) =
increased adverse effects
What is a Black Box Warning:
is considered a contraindication to administer that drug.
What is the drugs half-life?
Half-life specifically means the amount of time it takes for an administered drug to
be halfway cleared from the system.
Peak of action:
the time between drug administration and maximum concentration of drug in the
blood stream. Best therapeutic effect.
,Duration of action:
the time between onset of action and metabolism of drug below the minimum
needed for an effect. The length of time you have the drug in your system.
According to the WHO what is the first step in the prescribing process?
The first step is to define the patient's problem
The second step is to
specify the therapeutic objective
The third step is to
choose which drug or treatment is needed.
Step 4 of the WHO approach:
Start the treatment
Step 5 of the WHO approach:
,Educate the patient
Step 6 of the WHO approach:
Monitor the treatment
Phase 1 of drug development:
The drug is tested on healthy volunteers
Phase 2 of drug development:
trials with people who have the disease for which the drug is thought to be
effective
Phase 3 of drug development:
Large numbers of patients in medical research centers receive the drug in phase 3.
This larger sampling provides information about infrequent or rare adverse effects.
The FFA will approve a new drug application if phase 3 studies are satisfactory.
Phase 4 of drug development:
, This phase is voluntary and involves postmarket surveillance of the drug's
therapeutic effects at the completion of phase 3. The pharmaceutical company
receives reports from doctors and other health care professionals about the
therapeutic results and adverse effects of the drug. Some medications, for
example, have been found to be toxic and have been removed from the market
after their initial release.
Explain first pass metabolism
much of the drug is lost in the absorption process. The liver metabolizes many
drugs, thus reduces the bioavailability of the drug.
What is the fasted route of absorption:
The fastest route of absorption is inhalation, and not as mistakenly considered the
IV administration.
Why does the GI tract take longer to absorb?
The GI tract is lined with epithelial cells; drugs must permeate through these cells
in order to be absorbed into the circulatory system.
What is One particular cellular barrier that may prevent absorption of a given
drug?
