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CEN TOXICOLOGY MIDTERM EXAM TEST BANK QUESTIONS AND CORRECT ANSWERS WITH RATIONALES (VERIFIED ANSWERS) | LATEST 2026/2027 | ALREADY GRADED A+.

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CEN TOXICOLOGY MIDTERM EXAM TEST BANK QUESTIONS AND CORRECT ANSWERS WITH RATIONALES (VERIFIED ANSWERS) | LATEST 2026/2027 | ALREADY GRADED A+. What does muscular rigidity cause - CORRECT ANSWER rhabdomylosis syndrome due 2 | P a g e to a direct or indirect muscle injury. It results from the death of muscle fibers and release of their contents into the bloodstream (myoglobin). This can lead to renal (kidney) failure. sympathomimetic [fight or flight/shunt blood going to heart/brain/lungs] - CORRECT ANSWER MIMIC SYMPATHETIC a drug that stimulates the sympathetic branch of the autonomic nervous system Epinephrine, adrenaline Organophosphate poisoning Cholinergics {see, spit, pee, shit] used in pesticides b/c - CORRECT ANSWER BUGS DROWN with Cholinergic [producing fluids: saliva, urine, digestive enzymes] Organophosphates are used as insecticides, medications, and nerve agents. Symptoms include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, muscle tremors, and confusion. Cholinergics {see, spit, pee, shit] pathway - CORRECT ANSWER muscuric and nicotinic receptors that use acetylcholine neurotransmitters 3 | P a g e cholinergic cells that use which neurotransmitter - CORRECT ANSWER Referring to cells that use acetylcholine as their synaptic transmitter. antidote - CORRECT ANSWER 2-PAM Atropine anticholinergic over dose examples - CORRECT ANSWER Atropine antihistamines [benadryl] TCAs Tricyclic antidepressants (Amitriptyline) Cyclobenzapine (muscle relaxant) extrapyramidal effects are? - CORRECT ANSWER Extrapyramidal symptoms are most commonly caused by typical antipsychotic drugs that antagonize dopamine D2 receptors. The most common typical antipsychotics associated with EPS are haloperidol and fluphenazine. drug-induced movement disorders that include acute and tardive symptoms Saran Gas [nerve gas] - CORRECT ANSWER Within seconds of exposure to sarin gas 4 | P a g e (or liquid, which evaporates easily), we start to notice the immediate effects of acetylcholine buildup. First, our smooth muscles and secretions go crazy. The nerves to those areas keep firing, keep telling them to go Saran Gas nerve gas antidote - CORRECT ANSWER 2-PAM Cl Atropine and pralidoxime chloride (2-PAM Cl) are antidotes for nerve agent toxicity; however, 2PAM Cl must be administered within minutes to a few hours (depending on the agent) following exposure to be effective. There is also generally no benefit in giving more than three injections of 2-PAM Cl. SLUDGE-bbb - CORRECT ANSWER Muscarinic Cholinergic syndrome Salvation lacrimination urination defecation gastric emesis bronchoria bronchospasm bradycardia miosis increased bowel sounds 5 | P a g e Cholinergic Drug toxicity nerve gas tx - CORRECT ANSWER FIRST RESPONDERS AT THE SCENE atropine until they stop pouring fluid out of their face Pulmonary Edema Needs Positive Pressure Airway OD/Chronic use of benzodiapines (clonazepam diazepam, lorazepam) - CORRECT ANSWER Intractable Szes Special care should be taken in withdrawing benzodiazepines, as delirium, psychosis, and withdrawal seizures have been reported with

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CEN TOXICOLOGY MIDTERM EXAM TEST BANK
QUESTIONS AND CORRECT ANSWERS WITH RATIONALES
(VERIFIED ANSWERS) | LATEST 2026/2027 | ALREADY
GRADED A+

Anticholinergics [not producing fluids/blood to heart, lungs and brain]
syndrome

(antihistamines, bronchodilators, cyclic antidepressants, SLEEP AIDS) -
CORRECT
ANSWER>>> Hot as a hare (hyperthermia)
Red as a beet (flushed)
Dry as a bone [ANHYDROSIS (dry skin, urinary retention)
Blind as a bat (mydriasis)
Mad as a hatter (hallucinations, delirium, myoclonic jerking)


The antidote for anticholinergic toxicity is physostigmine salicylate.
Physostigmine is the only reversible acetylcholinesterase inhibitor
capable of directly antagonizing the CNS manifestations of
anticholinergic toxicity; it is an uncharged tertiary amine that efficiently
crosses the bloodbrain barrier



What does muscular rigidity cause - CORRECT ANSWER>>>
rhabdomylosis syndrome due



1|Page

,to a direct or indirect muscle injury. It results from the death of muscle
fibers and release of their contents into the bloodstream (myoglobin).
This can lead to renal (kidney) failure.


sympathomimetic [fight or flight/shunt blood going to heart/brain/lungs]
- CORRECT ANSWER>>> MIMIC SYMPATHETIC
a drug that stimulates the sympathetic branch of the autonomic nervous
system
Epinephrine, adrenaline


Organophosphate poisoning

Cholinergics {see, spit, pee, shit] used in pesticides b/c - CORRECT
ANSWER>>> BUGS DROWN with Cholinergic [producing fluids:
saliva, urine, digestive enzymes]
Organophosphates are used as insecticides, medications, and nerve
agents. Symptoms include increased saliva and tear production, diarrhea,
vomiting, small pupils, sweating, muscle tremors, and confusion.



Cholinergics {see, spit, pee, shit] pathway - CORRECT
ANSWER>>> muscuric and nicotinic receptors that use acetylcholine
neurotransmitters




2|Page

, cholinergic cells that use which neurotransmitter - CORRECT
ANSWER>>> Referring to cells that use acetylcholine as their
synaptic transmitter.



antidote - CORRECT ANSWER>>> 2-PAM
Atropine


anticholinergic over dose examples - CORRECT ANSWER>>>

Atropine antihistamines [benadryl]

TCAs Tricyclic antidepressants (Amitriptyline)
Cyclobenzapine (muscle relaxant)



extrapyramidal effects are? - CORRECT ANSWER>>>
Extrapyramidal symptoms are most commonly caused by typical
antipsychotic drugs that antagonize dopamine D2 receptors. The most
common typical antipsychotics associated with EPS are haloperidol and
fluphenazine.


drug-induced movement disorders that include acute and tardive
symptoms



Saran Gas [nerve gas] - CORRECT ANSWER>>> Within seconds
of exposure to sarin gas

3|Page

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