NRS 3025: Hematological Disorders - Questions
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Terms in this set (128)
• Genetic damage
• Ionizing radiation
What are general risk DRUG + CHEMICAL EXPOSURE
factors of heme • Benzenes
malignancies? • Alkylating agents (type of chemotherapy)
• Possibly genetics
• Viruses — Epstein-Barr Virus
Are there any screening None
methods for heme
malignancies?
• Malignant disease of blood forming organs
What is leukemia? • WBC precursors proliferate in the bone marrow +
lymphatic tissues
• Rapid onset and progression — can take weeks or
Describe acute leukemia. days
• 100% mortality within days/months if left untreated
What are the types of • Acute Lymphocytic Leukemia (ALL)
acute leukemia? • Acute Myeloid Leukemia (AML)
Describe chronic • Slower onset and progression
leukemia. • Don't necessarily need aggressive Tx
What are the types of • Chronic Lymphocytic Leukemia (CLL)
chronic leukemia? • Chronic Myeloid Leukemia (CML)
, • Mainly r/t bone marrow suppression
• Fatigue, weakness
• Low Hgb
• Bleeding, bruising, peteciae — THAT WON'T STOP
INFECTION THAT DOESN'T RESOLVE
What are the S/Sx r/t
• Sore throat
leukemia?
• Cough
• Skin infection
• GI infection
• Fever
• May be asymptomatic early
CBC
• Low Hgb, low PLT
• Low or extremely high WBC (50,000 — 100,000)
Describe Dx for
• Blast cells in the differential are NEVER normal
leukemia.
• Bone marrow aspiration and biopsy
• Lumbar puncture for acute lymphocytic leukemias
CHEMO
• Induction
What is included in Tx of • Consolidation
acute leukemia? • Maintenance
STEM CELL TRANSPLANT
What does chemo Strong and high doses to knock out leukemia
induction involve?
ADDRESSING PANCYTOPENIA
• Anemia
What is included in
• Thrombocytopenia
nursing care for
• Neutropenia
leukemia?
• Care for patient receiving chemotherapy
What are the types of • Hodgkin
lymphoma? • Non-Hodgkin (NHL)
, • Originates in a SINGLE NODE (but spreads via
What is Hodgkin lymph system
lymphoma? • Reed-Sternberg cell
• Relatively good prognosis
What is non-Hodgkin • Multiple subtypes
lymphoma (NHL)? • Prognosis varies based on subtype
• Lymphadenopathy
What are the S/Sx of
• Painless enlarged lymph nodes
lymphoma?
• Mediastinal mass — may lead to dyspnea
• One or more enlarged lymph nodes on the side of
What are S/Sx of the neck
Hodgkin's lymphoma? • Pruritus
• Pain after drinking alcohol
"B" Symptoms
What are S/Sx of Non- • Fever
Hodgkin's lymphoma? • Night sweats
• Unintentional weight loss
• Rule out infection!
What is involved in the • Excisional Bx of affected lymph node
Dx of lymphoma? • Looking for CD20 antigens on the cancer cells
• Reed-Sternberg cell (HL)
• CXR or CT of chest, abdomen, and pelvis
What is involved in
• CBC
staging lymphoma?
• Bone marrow aspiration + Bx
• Surgery
What is included in the
• Chemotherapy — address pancytopenia + Tx needs
treatment of lymphoma?
• Mantle field radiation
• Commonly given for HL that is above the
What is mantle field
diaphragm
radiation?
• May lead to breast cancer
• Malignancy of plasma cells
What is multiple
• Most mature form of B-lymphocyte
myeloma?
• Production of monoclonal protein (M protein)
With Precise Solutions
Save
Terms in this set (128)
• Genetic damage
• Ionizing radiation
What are general risk DRUG + CHEMICAL EXPOSURE
factors of heme • Benzenes
malignancies? • Alkylating agents (type of chemotherapy)
• Possibly genetics
• Viruses — Epstein-Barr Virus
Are there any screening None
methods for heme
malignancies?
• Malignant disease of blood forming organs
What is leukemia? • WBC precursors proliferate in the bone marrow +
lymphatic tissues
• Rapid onset and progression — can take weeks or
Describe acute leukemia. days
• 100% mortality within days/months if left untreated
What are the types of • Acute Lymphocytic Leukemia (ALL)
acute leukemia? • Acute Myeloid Leukemia (AML)
Describe chronic • Slower onset and progression
leukemia. • Don't necessarily need aggressive Tx
What are the types of • Chronic Lymphocytic Leukemia (CLL)
chronic leukemia? • Chronic Myeloid Leukemia (CML)
, • Mainly r/t bone marrow suppression
• Fatigue, weakness
• Low Hgb
• Bleeding, bruising, peteciae — THAT WON'T STOP
INFECTION THAT DOESN'T RESOLVE
What are the S/Sx r/t
• Sore throat
leukemia?
• Cough
• Skin infection
• GI infection
• Fever
• May be asymptomatic early
CBC
• Low Hgb, low PLT
• Low or extremely high WBC (50,000 — 100,000)
Describe Dx for
• Blast cells in the differential are NEVER normal
leukemia.
• Bone marrow aspiration and biopsy
• Lumbar puncture for acute lymphocytic leukemias
CHEMO
• Induction
What is included in Tx of • Consolidation
acute leukemia? • Maintenance
STEM CELL TRANSPLANT
What does chemo Strong and high doses to knock out leukemia
induction involve?
ADDRESSING PANCYTOPENIA
• Anemia
What is included in
• Thrombocytopenia
nursing care for
• Neutropenia
leukemia?
• Care for patient receiving chemotherapy
What are the types of • Hodgkin
lymphoma? • Non-Hodgkin (NHL)
, • Originates in a SINGLE NODE (but spreads via
What is Hodgkin lymph system
lymphoma? • Reed-Sternberg cell
• Relatively good prognosis
What is non-Hodgkin • Multiple subtypes
lymphoma (NHL)? • Prognosis varies based on subtype
• Lymphadenopathy
What are the S/Sx of
• Painless enlarged lymph nodes
lymphoma?
• Mediastinal mass — may lead to dyspnea
• One or more enlarged lymph nodes on the side of
What are S/Sx of the neck
Hodgkin's lymphoma? • Pruritus
• Pain after drinking alcohol
"B" Symptoms
What are S/Sx of Non- • Fever
Hodgkin's lymphoma? • Night sweats
• Unintentional weight loss
• Rule out infection!
What is involved in the • Excisional Bx of affected lymph node
Dx of lymphoma? • Looking for CD20 antigens on the cancer cells
• Reed-Sternberg cell (HL)
• CXR or CT of chest, abdomen, and pelvis
What is involved in
• CBC
staging lymphoma?
• Bone marrow aspiration + Bx
• Surgery
What is included in the
• Chemotherapy — address pancytopenia + Tx needs
treatment of lymphoma?
• Mantle field radiation
• Commonly given for HL that is above the
What is mantle field
diaphragm
radiation?
• May lead to breast cancer
• Malignancy of plasma cells
What is multiple
• Most mature form of B-lymphocyte
myeloma?
• Production of monoclonal protein (M protein)
