,ABRAMS' 5sCLINICAL 5sDRUG 5sTHERAPY: 5sRATIONALES 5sFOR 5sNURSING
5sPRACTICE
,ABRAMS' 5sCLINICAL 5sDRUG 5sTHERAPY: 5sRATIONALES 5sFOR 5sNURSING
5sPRACTICE
, ABRAMS' 5sCLINICAL 5sDRUG 5sTHERAPY: 5sRATIONALES 5sFOR 5sNURSING
5sPRACTICE
Chapter 5s1, 5sThe 5sFoundation 5sof 5sPharmacology: 5sQuality 5sand 5sSafety
1. A 5swoman 5sdiagnosed 5swith 5sobsessive–compulsive 5sdisorder 5shas 5sbeen
5sprescribed 5soral 5 s paroxetine 5shydrochloride. 5s What 5 s is 5sthe 5sexpected 5seffect
5s for 5sthis 5sprescription?
A. Curative 5seffect 5s on 5ssymptoms
B. Systemic 5seffect 5son 5ssymptoms
C. Local 5seffect 5son 5ssymptoms
D. Parenteral 5seffect 5son 5ssymptoms
ANS: 5s 5sB
Rationale: 5sDrugs 5sthat 5sproduce 5ssystemic 5seffects 5sare 5staken 5sinto 5sthe 5sbody, 5scirculated
5sthrough 5 s the 5sbloodstream 5sto 5stheir 5ssites 5sof 5saction 5sin 5svarious 5s body 5stissues, 5s and
5seventually 5seliminated 5 s from 5sthe 5sbody. 5s Curative 5sagents 5sare 5sgiven 5sto 5s cure 5sa
5sdisease 5sprocess. 5s In 5sthis 5scase, 5s paroxetine 5 s hydrochloride 5swill 5scontrol 5sthe 5ssymptoms
5sbut 5s not 5scure 5sthe 5sdisorder. 5sDrugs 5swith 5slocal 5seffects, 5 s such 5sas 5ssunscreen 5sand 5s local
5sanesthetics, 5s act 5s mainly 5sat 5sthe 5ssite 5sof 5sapplication. 5 s Paroxetine 5 s hydrochloride 5s is 5snot
5sadministered 5sparenterally. 5s Parenteral 5sagents 5sare 5sadministered 5 s subcutaneously,
5s intramuscularly, 5s or 5sintravenously.
PTS: 1 REF: p. 5s3, 5sIntroduction OBJ: 1
NAT: 5 s Client 5sNeeds: 5sPhysiological 5sIntegrity: 5sPharmacological 5sand 5sParenteral
5sTherapies 5 s TOP: Chapter: 5s1: 5sThe 5sFoundation 5sof 5sPharmacology: 5s Quality
5sand 5sSafety
KEY: 5 s Integrated 5sProcess: 5sNursing 5sProcess
BLM: 5s 5 s Cognitive 5s Level: 5sUnderstand NOT: 5 s Multiple 5sChoice
2. A 5sclient 5s has 5sbeen 5sprescribed 5san 5santibiotic. 5sThis 5smedication 5sis 5sa 5snaturally 5soccurring
substance 5sthat 5shas 5sbeen 5scheG mRicA
alDlyEm
SoBdOifOieSd.TWhaOt 5sM
.C is 5sanother 5sname 5sfor 5sthis 5stype 5sof
5smedication?
A. Synthetic 5sdrug
B. Semisynthetic 5sdrug
C. Biotechnology 5sdrug
D. Prototype 5sdrug
ANS: 5s 5sB
Rationale: 5sSemisynthetic 5sdrugs 5s(e.g., 5smany 5santibiotics) 5sare 5s naturally 5soccurring
5ssubstances 5 s that 5shave 5sbeen 5schemically 5smodified. 5sSynthetic 5sdrugs 5sare 5smore
5sstandardized 5s in 5stheir 5schemical 5 s characteristics, 5s more 5sconsistent 5s in 5stheir 5seffects, 5s and
5sless 5s likely 5sto 5s produce 5sallergic 5sreactions. 5 s Biotechnology 5sdrugs 5s involve 5s manipulating
5sDNA 5sand 5sRNA 5sand 5srecombining 5sgenes 5s into 5 s hybrid 5s molecules 5sthat 5s can 5sbe
5s inserted 5sinto 5sliving 5sorganisms. 5s Prototype 5sdrugs 5sare 5sthe 5sfirst 5 s drug 5sof 5sa 5sparticular
5s group 5sto 5s be 5sdeveloped.
PTS: 1 REF: p. 5s3, 5sDrug 5sSources OBJ: 1
NAT: 5 s Client 5sNeeds: 5sPhysiological 5sIntegrity: 5sPharmacological 5sand 5sParenteral
5sTherapies 5 s TOP: Chapter: 5s1: 5sThe 5sFoundation 5sof 5sPharmacology: 5sQuality
5sand 5sSafety
KEY: 5 s Integrated 5sProcess: 5sNursing 5sProcess
BLM: 5s 5 s Cognitive 5s Level: 5sUnderstand NOT: 5 s Multiple 5sChoice
3. Which 5sclassification 5sapplies 5sto 5smorphine?
A. Central 5snervous 5ssystem 5sdepressant
B. Central 5snervous 5ssystem 5sstimulant