Adverse Drug Reaction (ADR) Correct Answer Undesired
effect experienced by a patient that occurs during normal drug
dosing.
Adverse Effect of Aminoglycosides Correct Answer -
Ototoxicity
-Nephrotoxicity ( cause acute tubular necrosis)
-Neuromuscular blockade
Adverse effects of Amphotericin Correct Answer -infusion
reactions (fever, chills, rigors, nausea)
-Monitor renal impairment (Test kidney's every 3 to 4 days)
plasma creatinine test.
-Hypokalemia: Test serum potassium often.
-Hematologic effects: test hematocrit frequently
Adverse effects of Cephalosporins? Correct Answer -Allergic
Reaction
-Bleeding (Cefotetan,Ceftriaxone)
-Thrombophlebitis
-Hemolytic Anemia
-CDI
-Milk-protein hypersensitivity
-Carnitine Deficiency
-Alcohol intolerance(Cefazolin, cefotetan)
-Calcium and Ceftiaxone: form potentially fatal precipitates
Adverse effects of Flucytosine Correct Answer -Hematologic
effects: bone marrow suppression cause neutropenia.
,-keep flucytosine below 100 mcg-mL.
Hepatotoxicity
Adverse effects of Itraconazole Correct Answer -Liver Injury:
watch for persistent nausea, anorexia, fatigue, vomiting,
jaundice, dark urine, pale stools
-Cardiac suppression: Watch for fatigue, cough, dyspnea,
edema, jugular distension (heart failure signs)
Adverse effects of penicillin? Correct Answer -Allergic
reaction
-High IV doses can produce sodium overload (electrolytes and
cardiac status)
-Hyperkalemia: high doses of IV potassium penicillin G
(dysrhythmias or cardiac arrest)
-watch out for icorrect injecting into blood supply and peripheral
nerves.
Adverse Effects of Vancomycin? Correct Answer -Renal
Failure (Trough levels)
-Red Man Syndrome (slow down rate)
-Thrombophlebitis
Adverse reactions of Fluroquinolones Correct Answer -
Tendinitis or tendon rupture(report swelling, pain,
inflammation)
-Phototoxicity
-QT Prolongation
-Myasthenia Gravis
, Adverse reactions to sulfonamides Correct Answer -
Hypersenitivity reactions (Steven-Johnson Syndrome)
-Photosensitivity (avoid prolonged exposure, sunscreen,
protective clothing)
-Hematologic Effects (hemolytic anemia, blood
dyscrasias((Fever, pallor, jaundice))
-Kernicterus
-Renal Damage
Aminoglycosides (gentamycin) Correct Answer - Used to
treat gram negative bacilli
-Duo with vanco it can treat gram-positive bacilli like
Enterococcus, some streptococci, and Staph. Aureus
Amphotericin B Therapeutic effect? Correct Answer
Treatment of potentially fatal systemic fungal infections. No
contraindications.
Any administration instructions for Sulfonomides? Correct
Answer Empty stomach and a full glass of water.
Are Penicillins and Aminoglycosides compatable? (T/F)
Correct Answer F: Amino will be inactivated by high
concentrations of penicillins.
Assessment of Preoperative Patient Correct Answer Goal:
Identify risk factor and plan care to ensure patient safety
throughout the surgical experience
Actions: