Fundamentals of Chemotherapy Immunotherapy
Administration Test Questions with Correct Detailed
Verified Answers Best Scored!! Latest update
INTRODUCTION:
This document provides a complete collection of test questions and
answers covering chemotherapy and immunotherapy
administration. It includes detailed explanations on cancer
classifications, chemotherapy phases, mechanisms of action,
targeted therapy, immunotherapy (checkpoint inhibitors,
monoclonal antibodies, CAR T-cell therapy), and management of
side effects. The material also reviews safety protocols, competency
requirements, administration routes, and patient care
considerations, making it a valuable study resource for healthcare
professionals preparing for exams or clinical practice.
EXAM QUESTIONS AND ANSWERS:
Hydroxyurea --- correct answer ----antimetabolite/miscellaneous
-treats: leukemia, melanoma, inoperable ovarian, with radiation for
head/neck, prophylaxis of sickle-cell
-ORAL ONLY
,-consider risks with gout
Hormone therapy --- correct answer ----treatment that adds,
blocks, removes hormones
-hormones can cause cancers (ovarian, prostate)
-surgery may remove gland that produces hormone
-synthetic hormones may block natural hormones
Prostate cancer (hormone therapy) --- correct answer ----androgen
(testosterone) cause prostate cell growth
-androgen suppression decreases testosterone
-castration resistant (less effective over time)
Breast cancer (hormone therapy) --- correct answer ----hormone
receptor-positive (HR+) - most common
-goal: decrease estrogens/progestins
-treatment depends on (pre/post menopause)
Hormone receptor positive --- correct answer ----cells with proteins
that bind to specific hormones
-need estrogen or progesterone to grow
-can affect treatment
,Tamoxifen --- correct answer ----estrogen receptor antagonist &
receptor modulator
-HR+ breast CA
-binds to estrogen receptors, alters estrogen genes
-ORAL ONLY
-can increase ovulation (birth control)
Leuprolide --- correct answer ----breast and prostate CA
-block LHRH from hypothalamus, block hormone from anterior
pituitary gland
-Breast=IM q4w ---- Prostate=SC or IM q4-24w
-only FDA approved for prostate
Targeted therapy --- correct answer ----identify/attack specific
cancer cells, less harm to normal
-block action or deliver toxic substances to cancer cell
-fewer side effects to other treatments
Small molecule inhibitors --- correct answer ----tyrosine kinase
inhibitors (TKIs)
-Mammalian target of rapamycin (mTOR) inhibitors
, Tyrosine kinase inhibitors (TKIs) --- correct answer ---TK = direct
cell growth, signaling and division
-inhibiting them stops cancer cell growth
-drug-drug interaction - TKIs metabolized by CYP
Imatinib --- correct answer ----TKI
-leukemia
-ORAL ONLY
-monitor GI upset, and weight gain
Lapatinib --- correct answer ----targeted therapy
-breast CA
-ORAL ONLY
-decreased LVEF, no grapefruit juice
T-Cell (T lymphocyte) --- correct answer ----type of WBC
-part of immune system from stem cells in bone marrow
-protect body from infection, fight CA
B-Cell (B lymphocyte) --- correct answer ----type of WBC that make
antibodies
-part of immune system from stem cells in bone marrow
Administration Test Questions with Correct Detailed
Verified Answers Best Scored!! Latest update
INTRODUCTION:
This document provides a complete collection of test questions and
answers covering chemotherapy and immunotherapy
administration. It includes detailed explanations on cancer
classifications, chemotherapy phases, mechanisms of action,
targeted therapy, immunotherapy (checkpoint inhibitors,
monoclonal antibodies, CAR T-cell therapy), and management of
side effects. The material also reviews safety protocols, competency
requirements, administration routes, and patient care
considerations, making it a valuable study resource for healthcare
professionals preparing for exams or clinical practice.
EXAM QUESTIONS AND ANSWERS:
Hydroxyurea --- correct answer ----antimetabolite/miscellaneous
-treats: leukemia, melanoma, inoperable ovarian, with radiation for
head/neck, prophylaxis of sickle-cell
-ORAL ONLY
,-consider risks with gout
Hormone therapy --- correct answer ----treatment that adds,
blocks, removes hormones
-hormones can cause cancers (ovarian, prostate)
-surgery may remove gland that produces hormone
-synthetic hormones may block natural hormones
Prostate cancer (hormone therapy) --- correct answer ----androgen
(testosterone) cause prostate cell growth
-androgen suppression decreases testosterone
-castration resistant (less effective over time)
Breast cancer (hormone therapy) --- correct answer ----hormone
receptor-positive (HR+) - most common
-goal: decrease estrogens/progestins
-treatment depends on (pre/post menopause)
Hormone receptor positive --- correct answer ----cells with proteins
that bind to specific hormones
-need estrogen or progesterone to grow
-can affect treatment
,Tamoxifen --- correct answer ----estrogen receptor antagonist &
receptor modulator
-HR+ breast CA
-binds to estrogen receptors, alters estrogen genes
-ORAL ONLY
-can increase ovulation (birth control)
Leuprolide --- correct answer ----breast and prostate CA
-block LHRH from hypothalamus, block hormone from anterior
pituitary gland
-Breast=IM q4w ---- Prostate=SC or IM q4-24w
-only FDA approved for prostate
Targeted therapy --- correct answer ----identify/attack specific
cancer cells, less harm to normal
-block action or deliver toxic substances to cancer cell
-fewer side effects to other treatments
Small molecule inhibitors --- correct answer ----tyrosine kinase
inhibitors (TKIs)
-Mammalian target of rapamycin (mTOR) inhibitors
, Tyrosine kinase inhibitors (TKIs) --- correct answer ---TK = direct
cell growth, signaling and division
-inhibiting them stops cancer cell growth
-drug-drug interaction - TKIs metabolized by CYP
Imatinib --- correct answer ----TKI
-leukemia
-ORAL ONLY
-monitor GI upset, and weight gain
Lapatinib --- correct answer ----targeted therapy
-breast CA
-ORAL ONLY
-decreased LVEF, no grapefruit juice
T-Cell (T lymphocyte) --- correct answer ----type of WBC
-part of immune system from stem cells in bone marrow
-protect body from infection, fight CA
B-Cell (B lymphocyte) --- correct answer ----type of WBC that make
antibodies
-part of immune system from stem cells in bone marrow
