TEST BANK For Basic and Clinical Pharmacology, 15th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version

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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is havin
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g a computed tomography (CT) scan. The nurse working on the oncology u
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nit administers chemotherapy to patients who have cancer. At the Public He
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alth Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology best de
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scribes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
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Pharmacology is the study of the biologic effects of chemicals. Nurses are i
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nvolved with clinical pharmacology or pharmacotherapeutics, which is a bra
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nch of pharmacology that deals with the uses of drugs to treat, prevent, and
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diagnose disease. The radiology nurse is administering a drug to help diagn
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ose a disease. The oncology nurse is administering a drug to help treat a dise
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ase. Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and pharmacokinetic yr yr yr yr yr yr yr yr yr


s is how the body acts on the body.
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2.
When involved in phase III drug evaluation studies, wh
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at responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
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Phase III studies involve use of a drug in a vast clinical population in which
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patients are asked to record any symptoms they experience while taking the
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drugs. Nurses may be responsible for helping collect and analyze the infor
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mation to be shared with the Food and Drug Administration (FDA) but woul
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d not conduct research independently because nurses do not prescribe medi
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cations. Use of animals in drug testing is done in the preclinical trials. Selec
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t patients who are involved in phase II studies to participate in studies wher
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e the participants have the disease the drug is intended to treat. These patien
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ts are monitored closely for drug action and adverse effects. Phase I studies
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involve healthy human volunteers who are usually paid for their participatio
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n. Nurses may observe for adverse effects and toxicity.
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3.
A physician has ordered intramuscular (IM) injections of morphine, a nar
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cotic, every 4 hours as needed for pain in a motor vehicle accident victim. T
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he nurse is aware this drug has a high abuse potential. Under what category
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would morphine be classified? yr yr yr




A) Schedule I yr




B) Schedule II yr




C) Schedule III yr




D) Schedule IV yr




Ans: B
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Narcotics with a high abuse potential are classified as Schedule II drugs be
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cause of severe dependence liability. Schedule I drugs have high abuse pot
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ential and no accepted medical use. Schedule III drugs have a lesser abuse
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potential than II and an accepted medical use. Schedule IV drugs have low a
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buse potential and limited dependence liability.
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4.
What concept is considered when generic drugs are substituted for bra
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nd name drugs?
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A) Bioavailability

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