FULLTESTBANK
TEST BANK FOR ADVANCED PHYSIOLOGY AND
PATHOPHYSIOLOGY 2ND EDITION BY NANCY
TKACS COMPLETE GUIDE.
PRINTED PDF | ORIGINAL DIRECTLY FROM THE PUBLISHER | 100%
VERIFIED ANSWERS | DOWNLOAD IMMEDIATELY AFTER THE ORDER
, TABLE OF CONTENTS
Chapter 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL PRACTICE
Chapter 2. CHEMICAL AND BIOCHEMICAL FOUNDATIONS
Chapter 3. MOLECULAR BIOLOGY, GENETICS, AND GENETIC DISEASES
Chapter 4. CELL PHYSIOLOGY AND PATHOPHYSIOLOGY
Chapter 5. INFECTIOUS DISEASE
Chapter 6. THE IMMUNE SYSTEM
Chapter 7. NEOPLASIA
Chapter 8. BLOOD AND CLOTTING
Chapter 9. CIRCULATION
Chapter 10. HEART
Chapter 11. LUNGS
Chapter 12. KIDNEYS
Chapter 13. GASTROINTESTINAL TRACT
Chapter 14. LIVER
Chapter 15. NERVOUS SYSTEM
Chapter 16. MUSCULOSKELETAL SYSTEM
Chapter 17. ENDOCRINE SYSTEM
, Advanced Physiology and Pathophysiology Essentials for
Clinical Practice 2nd Edition Tkacs Test Bank
CHAPTER 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL
PRACTICE
1. The characteristic, localized cardinal signs OF acute inflammation include:
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage OF acute inflammation is initiated by
momentary vasoconstriction followed by vasodilation that causes localized:
A) bleeding.
B) congestion.
C) pale skin.
D) coolness.
3. The Cellular stage OF acute inflammation is marked by the movement of
leukocytes into the area. Which of the following cells arrives early in
great numbers?
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
,4. The phagocytosis process involves three distinct steps. What is the initial
step in the process?
A) Engulfment
B) Intracellular killing
C) Antigen margination
D) Recognition and adherence
5. WHICH OF the following mediators OF inflammation causes
increasedcapillary permeability and pain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide
6. Inflammatory exudates are a combination OF several types. WHICH
OFthe following exudates is composed OF enmeshed necrotic CELLs?
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours OF the
onset OF inflammation and includes:
A) fever and lethargy.
B) decreased C-reactive protein.
C) positive nitrogen balance.
D) low erythrocyte sedimentation rate.
8. In contrast to acute inflammation, chronic inflammation is characterized by
WHICH OF the following phenomena?
,A) Profuse fibrinous exudation
B) A shift to the left OF granulocytes
C) Metabolic and respiratory alkalosis
D) Lymphocytosis and activated macrophages
9. Exogenous pyrogens (interleukin-1) and the presence OF bacteria in the
bloodlead to the release OF endogenous pyrogens that:
A) stabilize thermal control in the brain.
B) produce leukocytosis and anorexia.
C) block viral replication in CELLs.
D) inhibit prostaglandin release.
10 An older adult patient has just sheared the skin on her elbow while attempted
. to boost herself up in bed, an event that has precipitated acute inflammation
in the region surrounding the wound. WHICH OF the following events will
occur during the vascular stage OF the patients inflammation?
A) Outpouring OF exudate into interstitial spaces
B) Chemotaxis
C) Accumulation OF leukocytes along the epithelium
D) Phagocytosis OF CELLular debris
11 WHICH OF the following individuals most likely has the highest risk OF
. experiencing chronic inflammation?
A) A patient who has recently been diagnosed with type 2 diabetes
B) A patient who is a carrier OF an antibiotic-resistant organism
C) A patient who is taking oral antibiotics for an upper respiratory infection
D) A patient who is morbidly obese and who has a sedentary lifestyle
12 WHICH OF the following core body temperatures is within normal range?
.
A) 35.9C (96.6F)
,B) 38.0C (100.4F)
C) 35.5C (95.9F)
D) 37.3C (99.1F)
13 A postsurgical patient who is recovering in the postanesthetic recovery unit
. states that she is freezing cold. WHICH OF the following measures is
likelytobe initiated in the patients hypothalamus in an effort to reduce heat
loss?
A) Opening OF arteriovenous (AV) shunts
B) Reduced exhalation OF warmed air
C) Contraction OF pilomotor muscles
D) Decreased urine production
14 An elderly patient is dressed only in a hospital gown and complains OF a
. draft in her room. Consequently, she has requested a warm blanket while she
sits in her wheelchair. WHICH OF the following mechanisms OF heat loss is
most likely the primary cause OF her request?
A) Evaporation and conduction
B) Radiation and convection
C) Conduction and convection
D) Convection and evaporation
15 WHICH OF the following pathophysiologic processes are capable OF inducing
. the production OF pyrogens? Select all that apply.
A) Acute inflammation
B) Obesity
C) Myocardial infarction
D) Malignancy
E) Renal failure
16 WHICH OF the following patients is most likely to be susceptible to
. developing a neurogenic fever?
,A) A patient who has stage II Alzheimer disease
B) A patient who has sustained a head injury in a bicycle crash
C) A patient who has become delirious after the administration OF
abenzodiazepine
D) A patient who has begun taking a selective serotonin-reuptake inhibitor
(SSRI) for the treatment OF depression
17 Patients are commonly administered antipyretics when their oral temperature
. exceeds 37.5C (99.5F). WHICH OF the following statements related
totherationale for this action is most accurate?
A) Temperatures in excess OF 37.5C (99.5F) can result in seizure activity.
B) Lower temperatures inhibit the protein synthesis OF bacteria.
C) There is little empirical evidence for this treatment modality.
D) Most common antipyretics have been shown to have little effect on core
temperature.
18 A patient has sought care because OF recent malaise and high fever. Upon
. assessment, the patient states that his current fever began two days earlier,
although he states that for the last 2 weeks he is in a cycle OF high fever for
acouple OF days followed by a day or two OF normal temperature. WHICH
OF the following fever patterns is this patient experiencing?
A) Recurrent fever
B) Remittent fever
C) Sustained fever
D) Intermittent fever
19 A febrile, 3-week-old infant has been brought to the emergency department
. by his parents and is currently undergoing a diagnostic workup to determine
the cause OF his fever. WHICH OF the following statements best conveys
the rationale for this careful examination?
A) The immature hypothalamus is unable to perform normal
thermoregulation.
, B) Infants are susceptible to serious infections because OF their
decreasedimmune function.
C) Commonly used antipyretics OFten have no effect on the core
temperatureOF infants.
D) Fever in neonates is OFten evidence OF a congenital disorder rather than
aninfection.
20 An 84-year-old patients blood cultures have come back positive, despite the
. fact that his oral temperature has remained within normal range.
WHICHOFthe following phenomena underlies the alterations in fever
response that occur in the elderly?
A) Disturbance in the functioning OF the thermoregulatory center
B) Increased heat loss by evaporation
C) The presence OF comorbidities that are associated with lowered
coretemperature
D) Persistent closure OF arteriovenous shunts
ANSWER KEY::
1. C
2. B
3. C
4. D
5. C
6. D
7. A
8. D
9. B
10 A
.
11 D
.
, 12 D
.
13 C
.
14 B
.
15 A, C, D
.
16 B
.
17 C
.
18 D
.
19 B
.
20 A
.
SECTION 2. CHEMICAL AND BIOCHEMICAL FOUNDATIONS
1. Ischemia and other toxic injuries increase the accumulation OF
intraCELLularcalcium as a result OF:
A) release OF stored calcium from the mitochondria.
B) improved intraCELLular volume regulation.
C) decreased influx across the CELL membrane.
D) attraction OF calcium to fatty infiltrates.
2. The patient is found to have liver disease, resulting in the removal OF a lobe
OF his liver. Adaptation to the reduced size OF the liver leads to
OF the remaining liver CELLs.
, A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
3. A person eating peanuts starts choking and collapses. His airway obstruction
is partially cleared, but he remains hypoxic until he reaches the hospital. The
prolonged CELL hypoxia caused a cerebral infarction and resulting
in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
4. Bacteria and viruses cause CELL damage by , WHICH is unique
fromthe intraCELLular damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
D) decreasing protein synthesis and function
5. The patient has a prolonged interruption in arterial blood flow to his left
kidney, causing hypoxic CELL injury and the release OF free radicals.
Freeradicals damage CELLs by:
A) destroying phospholipids in the CELL membrane.
B) altering the immune response OF the CELL.
C) disrupting calcium storage in the CELL.
D) inactivation OF enzymes and mitochondria.
6. Injured CELLs have impaired flow OF substances through the CELL
membraneasa result OF:
TEST BANK FOR ADVANCED PHYSIOLOGY AND
PATHOPHYSIOLOGY 2ND EDITION BY NANCY
TKACS COMPLETE GUIDE.
PRINTED PDF | ORIGINAL DIRECTLY FROM THE PUBLISHER | 100%
VERIFIED ANSWERS | DOWNLOAD IMMEDIATELY AFTER THE ORDER
, TABLE OF CONTENTS
Chapter 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL PRACTICE
Chapter 2. CHEMICAL AND BIOCHEMICAL FOUNDATIONS
Chapter 3. MOLECULAR BIOLOGY, GENETICS, AND GENETIC DISEASES
Chapter 4. CELL PHYSIOLOGY AND PATHOPHYSIOLOGY
Chapter 5. INFECTIOUS DISEASE
Chapter 6. THE IMMUNE SYSTEM
Chapter 7. NEOPLASIA
Chapter 8. BLOOD AND CLOTTING
Chapter 9. CIRCULATION
Chapter 10. HEART
Chapter 11. LUNGS
Chapter 12. KIDNEYS
Chapter 13. GASTROINTESTINAL TRACT
Chapter 14. LIVER
Chapter 15. NERVOUS SYSTEM
Chapter 16. MUSCULOSKELETAL SYSTEM
Chapter 17. ENDOCRINE SYSTEM
, Advanced Physiology and Pathophysiology Essentials for
Clinical Practice 2nd Edition Tkacs Test Bank
CHAPTER 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL
PRACTICE
1. The characteristic, localized cardinal signs OF acute inflammation include:
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage OF acute inflammation is initiated by
momentary vasoconstriction followed by vasodilation that causes localized:
A) bleeding.
B) congestion.
C) pale skin.
D) coolness.
3. The Cellular stage OF acute inflammation is marked by the movement of
leukocytes into the area. Which of the following cells arrives early in
great numbers?
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
,4. The phagocytosis process involves three distinct steps. What is the initial
step in the process?
A) Engulfment
B) Intracellular killing
C) Antigen margination
D) Recognition and adherence
5. WHICH OF the following mediators OF inflammation causes
increasedcapillary permeability and pain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide
6. Inflammatory exudates are a combination OF several types. WHICH
OFthe following exudates is composed OF enmeshed necrotic CELLs?
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours OF the
onset OF inflammation and includes:
A) fever and lethargy.
B) decreased C-reactive protein.
C) positive nitrogen balance.
D) low erythrocyte sedimentation rate.
8. In contrast to acute inflammation, chronic inflammation is characterized by
WHICH OF the following phenomena?
,A) Profuse fibrinous exudation
B) A shift to the left OF granulocytes
C) Metabolic and respiratory alkalosis
D) Lymphocytosis and activated macrophages
9. Exogenous pyrogens (interleukin-1) and the presence OF bacteria in the
bloodlead to the release OF endogenous pyrogens that:
A) stabilize thermal control in the brain.
B) produce leukocytosis and anorexia.
C) block viral replication in CELLs.
D) inhibit prostaglandin release.
10 An older adult patient has just sheared the skin on her elbow while attempted
. to boost herself up in bed, an event that has precipitated acute inflammation
in the region surrounding the wound. WHICH OF the following events will
occur during the vascular stage OF the patients inflammation?
A) Outpouring OF exudate into interstitial spaces
B) Chemotaxis
C) Accumulation OF leukocytes along the epithelium
D) Phagocytosis OF CELLular debris
11 WHICH OF the following individuals most likely has the highest risk OF
. experiencing chronic inflammation?
A) A patient who has recently been diagnosed with type 2 diabetes
B) A patient who is a carrier OF an antibiotic-resistant organism
C) A patient who is taking oral antibiotics for an upper respiratory infection
D) A patient who is morbidly obese and who has a sedentary lifestyle
12 WHICH OF the following core body temperatures is within normal range?
.
A) 35.9C (96.6F)
,B) 38.0C (100.4F)
C) 35.5C (95.9F)
D) 37.3C (99.1F)
13 A postsurgical patient who is recovering in the postanesthetic recovery unit
. states that she is freezing cold. WHICH OF the following measures is
likelytobe initiated in the patients hypothalamus in an effort to reduce heat
loss?
A) Opening OF arteriovenous (AV) shunts
B) Reduced exhalation OF warmed air
C) Contraction OF pilomotor muscles
D) Decreased urine production
14 An elderly patient is dressed only in a hospital gown and complains OF a
. draft in her room. Consequently, she has requested a warm blanket while she
sits in her wheelchair. WHICH OF the following mechanisms OF heat loss is
most likely the primary cause OF her request?
A) Evaporation and conduction
B) Radiation and convection
C) Conduction and convection
D) Convection and evaporation
15 WHICH OF the following pathophysiologic processes are capable OF inducing
. the production OF pyrogens? Select all that apply.
A) Acute inflammation
B) Obesity
C) Myocardial infarction
D) Malignancy
E) Renal failure
16 WHICH OF the following patients is most likely to be susceptible to
. developing a neurogenic fever?
,A) A patient who has stage II Alzheimer disease
B) A patient who has sustained a head injury in a bicycle crash
C) A patient who has become delirious after the administration OF
abenzodiazepine
D) A patient who has begun taking a selective serotonin-reuptake inhibitor
(SSRI) for the treatment OF depression
17 Patients are commonly administered antipyretics when their oral temperature
. exceeds 37.5C (99.5F). WHICH OF the following statements related
totherationale for this action is most accurate?
A) Temperatures in excess OF 37.5C (99.5F) can result in seizure activity.
B) Lower temperatures inhibit the protein synthesis OF bacteria.
C) There is little empirical evidence for this treatment modality.
D) Most common antipyretics have been shown to have little effect on core
temperature.
18 A patient has sought care because OF recent malaise and high fever. Upon
. assessment, the patient states that his current fever began two days earlier,
although he states that for the last 2 weeks he is in a cycle OF high fever for
acouple OF days followed by a day or two OF normal temperature. WHICH
OF the following fever patterns is this patient experiencing?
A) Recurrent fever
B) Remittent fever
C) Sustained fever
D) Intermittent fever
19 A febrile, 3-week-old infant has been brought to the emergency department
. by his parents and is currently undergoing a diagnostic workup to determine
the cause OF his fever. WHICH OF the following statements best conveys
the rationale for this careful examination?
A) The immature hypothalamus is unable to perform normal
thermoregulation.
, B) Infants are susceptible to serious infections because OF their
decreasedimmune function.
C) Commonly used antipyretics OFten have no effect on the core
temperatureOF infants.
D) Fever in neonates is OFten evidence OF a congenital disorder rather than
aninfection.
20 An 84-year-old patients blood cultures have come back positive, despite the
. fact that his oral temperature has remained within normal range.
WHICHOFthe following phenomena underlies the alterations in fever
response that occur in the elderly?
A) Disturbance in the functioning OF the thermoregulatory center
B) Increased heat loss by evaporation
C) The presence OF comorbidities that are associated with lowered
coretemperature
D) Persistent closure OF arteriovenous shunts
ANSWER KEY::
1. C
2. B
3. C
4. D
5. C
6. D
7. A
8. D
9. B
10 A
.
11 D
.
, 12 D
.
13 C
.
14 B
.
15 A, C, D
.
16 B
.
17 C
.
18 D
.
19 B
.
20 A
.
SECTION 2. CHEMICAL AND BIOCHEMICAL FOUNDATIONS
1. Ischemia and other toxic injuries increase the accumulation OF
intraCELLularcalcium as a result OF:
A) release OF stored calcium from the mitochondria.
B) improved intraCELLular volume regulation.
C) decreased influx across the CELL membrane.
D) attraction OF calcium to fatty infiltrates.
2. The patient is found to have liver disease, resulting in the removal OF a lobe
OF his liver. Adaptation to the reduced size OF the liver leads to
OF the remaining liver CELLs.
, A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
3. A person eating peanuts starts choking and collapses. His airway obstruction
is partially cleared, but he remains hypoxic until he reaches the hospital. The
prolonged CELL hypoxia caused a cerebral infarction and resulting
in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
4. Bacteria and viruses cause CELL damage by , WHICH is unique
fromthe intraCELLular damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
D) decreasing protein synthesis and function
5. The patient has a prolonged interruption in arterial blood flow to his left
kidney, causing hypoxic CELL injury and the release OF free radicals.
Freeradicals damage CELLs by:
A) destroying phospholipids in the CELL membrane.
B) altering the immune response OF the CELL.
C) disrupting calcium storage in the CELL.
D) inactivation OF enzymes and mitochondria.
6. Injured CELLs have impaired flow OF substances through the CELL
membraneasa result OF:
