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BLOOD PHYSIOLOGY

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Exam of 74 pages for the course BLOOD PHYSIOLOGY at BLOOD PHYSIOLOGY (BLOOD PHYSIOLOGY)

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The Rawalpindi Medical University




BLOOD PHYSIOLOGY
By:-
Dr. Ali Zain
MBBS, RMP
FCPS PGR
PHYSIOLOGY DEP.

, The Rawalpindi Medical University




LEARNING OBJECTIVES
At the end of the discussion, students will be able:


• To discuss briefly composition of blood.

• To understand the concept of structure of RBCs.

• To differentiate the structure of haemoglobin types.

• To discuss all phases of Erythropoiesis and role of different
factors affecting it.

• To have complete concept of IRON METABOLISM.

, The Rawalpindi Medical University




Introduction:-
BLOOD



BLOOD CELLS 45% BLOOD PLASMA 55%.
(RBCs, WBCs, Platelets) (water, proteins, nitrates, gases, ions, wastes)

FUNCTIONS OF BLOOD Coagulation factors
Nutritive function Antibodies
Albumin
Respiratory function
Fibrinogen
Excretory function PLASMA – FIBRINOGEN = SERUM
Transport
Water balance
Acid base balance
Storage
Immunity
Regulation of body temperature

, The Rawalpindi Medical University




RED BLOOD CELLs:-
Biconcove (membrane> material)


CO2 Transport Oxygen Transport Acid base buffer
Carbonic anhydrase (haemoglobin)
enzyme

100ml blood à 45ml RBCs
100ml RBCs. à 34g
hemoglobin
100ml blood. à 15g
hemoglobin
1gm Hb. à 1.34ml
oxygen
100ml Blood à 20ml
oxygen

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