Test Bank
Cellular And Molecular Immunology
Abul Abbas, Andrew Lichtman, And Shiv Pillai
11th Edition
,
,Table Of Contents
Chapter 01 Properties And Overview Of Immune Responses 1
Chapter 02 CellS And Tissues Of The Immune System 3
Chapter 03 Leukocyte Circulation And Migration Into Tissues 6
Chapter 04 Innate Immunity 10
Chapter 05 Antibodies And Antigens 17
Chapter 06 Antigen Presentation To T Lymphocytes And The Functions Of Major
Histocompatibility Complex Molecules 20
Chapter 07 Immune Receptors And Signal Transduction 27
Chapter 08 Lymphocyte Development And Antigen Receptor Gene Rearrangement 30
Chapter 09 Activation Of T Lymphocytes 34
Chapter 10 Differentiation And Functions Of Cd4+ Effector T CellS 38
Chapter 11 Differentiation And Functions Of Cd8+ Effector T CellS 42
Chapter 12 B Cell Activation And Antibody Production 46
Chapter 13 Effector Mechanisms Of Humoral Immunity 52
Chapter 14 Specialized Immunity At Epithelial Barriers And In Immune Privileged Tissues 56
Chapter 15 Immunologic Tolerance And Autoimmunity 62
Chapter 16 Immunity To Microbes 67
Chapter 17 Transplantation Immunology 72
Chapter 18 Tumor Immunology 77
Chapter 19 Hypersensitivity Disorders 81
Chapter 20 Allergy 86
Chapter 21 Primary And Acquired Immunodeficiencies 89
, Chapter 01: Properties And Overview Of Immune Responses
Abbas, Lichtman, And Pillai: Cellular And Molecular Immunology, 11th Edition
Multiple Choice
1. The Principal Function Of The Immune System Is:
a. Defense Against Cancer
b. Repair Of Injured Tissues
c. Defense Against Microbial Infections
d. Prevention Of Inflammatory Diseases
e. Protection Against Environmental Toxins
SOLUTION:C
The Immune System Has Evolved In The Setting Of Selective Pressures Imposed By
Microbial Infections. Although Immune Responses To Cancer May Occur, The Concept
That “Immunosurveillance” Against Cancer Is A Principal Function Of The Immune
System Is Controversial. Repair Of Injured Tissues May Be A Secondary Consequence Of
The Immune Responses And Inflammation. Although The Immune System Has Regulatory
Features That Are Needed To Prevent Excessive Inflammation, Prevention Of
Inflammatory Diseases Is Not A Primary Function. The Immune System Can Protect
Against Microbial Toxins, But It Generally Does Not Offer Protection Against Toxins Of
Nonbiologic Origin.
2. Which Of The Following Infectious Diseases Was Prevented By The First
Successful Vaccination?
a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
SOLUTION:C
In 1798, Edward Jenner Reported The First Intentional Successful Vaccination, Which
Was Against Smallpox In A Boy, Using Material From The Cowpox Pustules Of A
Milkmaid. In 1980, Smallpox Was Reported To Be Eradicated Worldwide By A
Vaccination Program. Effective Vaccines Against Tetanus Toxin, Rubella Virus, And
Poliovirus Were Developed In The 20th Century And Are Widely Used. There Is No
Effective Vaccine Against Mycobacterium Tuberculosis.
3. Which Of The Following Is A Unique Property Of The Adaptive Immune System?
a. Highly Diverse Repertoire Of Specificities For Antigens
b. Self-Nonself Discrimination
c. Recognition Of Microbial Structures By Both Cell-Associated And Soluble Receptors
d. Protection Against Viral Infections
e. Responses That Have The Same Kinetics And Magnitude On Repeated Exposure
To The Same Microbe
SOLUTION:A
Cellular And Molecular Immunology
Abul Abbas, Andrew Lichtman, And Shiv Pillai
11th Edition
,
,Table Of Contents
Chapter 01 Properties And Overview Of Immune Responses 1
Chapter 02 CellS And Tissues Of The Immune System 3
Chapter 03 Leukocyte Circulation And Migration Into Tissues 6
Chapter 04 Innate Immunity 10
Chapter 05 Antibodies And Antigens 17
Chapter 06 Antigen Presentation To T Lymphocytes And The Functions Of Major
Histocompatibility Complex Molecules 20
Chapter 07 Immune Receptors And Signal Transduction 27
Chapter 08 Lymphocyte Development And Antigen Receptor Gene Rearrangement 30
Chapter 09 Activation Of T Lymphocytes 34
Chapter 10 Differentiation And Functions Of Cd4+ Effector T CellS 38
Chapter 11 Differentiation And Functions Of Cd8+ Effector T CellS 42
Chapter 12 B Cell Activation And Antibody Production 46
Chapter 13 Effector Mechanisms Of Humoral Immunity 52
Chapter 14 Specialized Immunity At Epithelial Barriers And In Immune Privileged Tissues 56
Chapter 15 Immunologic Tolerance And Autoimmunity 62
Chapter 16 Immunity To Microbes 67
Chapter 17 Transplantation Immunology 72
Chapter 18 Tumor Immunology 77
Chapter 19 Hypersensitivity Disorders 81
Chapter 20 Allergy 86
Chapter 21 Primary And Acquired Immunodeficiencies 89
, Chapter 01: Properties And Overview Of Immune Responses
Abbas, Lichtman, And Pillai: Cellular And Molecular Immunology, 11th Edition
Multiple Choice
1. The Principal Function Of The Immune System Is:
a. Defense Against Cancer
b. Repair Of Injured Tissues
c. Defense Against Microbial Infections
d. Prevention Of Inflammatory Diseases
e. Protection Against Environmental Toxins
SOLUTION:C
The Immune System Has Evolved In The Setting Of Selective Pressures Imposed By
Microbial Infections. Although Immune Responses To Cancer May Occur, The Concept
That “Immunosurveillance” Against Cancer Is A Principal Function Of The Immune
System Is Controversial. Repair Of Injured Tissues May Be A Secondary Consequence Of
The Immune Responses And Inflammation. Although The Immune System Has Regulatory
Features That Are Needed To Prevent Excessive Inflammation, Prevention Of
Inflammatory Diseases Is Not A Primary Function. The Immune System Can Protect
Against Microbial Toxins, But It Generally Does Not Offer Protection Against Toxins Of
Nonbiologic Origin.
2. Which Of The Following Infectious Diseases Was Prevented By The First
Successful Vaccination?
a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
SOLUTION:C
In 1798, Edward Jenner Reported The First Intentional Successful Vaccination, Which
Was Against Smallpox In A Boy, Using Material From The Cowpox Pustules Of A
Milkmaid. In 1980, Smallpox Was Reported To Be Eradicated Worldwide By A
Vaccination Program. Effective Vaccines Against Tetanus Toxin, Rubella Virus, And
Poliovirus Were Developed In The 20th Century And Are Widely Used. There Is No
Effective Vaccine Against Mycobacterium Tuberculosis.
3. Which Of The Following Is A Unique Property Of The Adaptive Immune System?
a. Highly Diverse Repertoire Of Specificities For Antigens
b. Self-Nonself Discrimination
c. Recognition Of Microbial Structures By Both Cell-Associated And Soluble Receptors
d. Protection Against Viral Infections
e. Responses That Have The Same Kinetics And Magnitude On Repeated Exposure
To The Same Microbe
SOLUTION:A
