TEST BANK For Basic and Clinical Pharmacology, 15th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version

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BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION K
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ATZUNG TREVOR TEST BANK
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INCLUSIVE OF CHAPTERS 1-66 COMPLETE WITH EXPLAINED ANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is h
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aving a computed tomography (CT) scan. The nurse working on the onc
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ology unit administers chemotherapy to patients who have cancer. At the
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Public Health Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology bes
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t describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses
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are involved with clinical pharmacology or pharmacotherapeutics, which
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is a branch of pharmacology that deals with the uses of drugs to treat,
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prevent, and diagnose disease. The radiology nurse is administering a dr
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ug to help diagnose a disease. The oncology nurse is administering a dr
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ug to help treat a disease. Pharmacoeconomics includes any costs involv
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ed in drug therapy.
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Pharmacodynamics involves how a drug affects the body and pharmacokin mb mb mb mb mb mb mb mb mb


etics is how the body acts on the body.
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2.
When involved in phase III drug evaluation studies,
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what responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:

Phase III studies involve use of a drug in a vast clinical population in
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which patients are asked to record any symptoms they experience while
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btaking the drugs. Nurses may be responsible for helping collect and ana
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lyze the information to be shared with the Food and Drug Administratio
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n (FDA) but would not conduct research independently because nurses
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do not prescribe medications. Use of animals in drug testing is done in
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bthe preclinical trials. Select patients who are involved in phase II studie
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s to participate in studies where the participants have the disease the dr
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ug is intended to treat. These patients are monitored closely for drug ac
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tion and adverse effects. Phase I studies involve healthy human volunte
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ers who are usually paid for their participation. Nurses may observe for
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mbadverse effects and toxicity. mb mb mb




3.
A physician has ordered intramuscular (IM) injections of morphine, a
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bnarcotic, every 4 hours as needed for pain in a motor vehicle accident v
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ictim. The nurse is aware this drug has a high abuse potential. Under w
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hat category would morphine be classified?
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A) Schedule I mb




B) Schedule II mb




C) Schedule III mb




D) Schedule IV mb




Ans: B
Feedback:

Narcotics with a high abuse potential are classified as Schedule II dru
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gs because of severe dependence liability. Schedule I drugs have high
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abuse potential and no accepted medical use. Schedule III drugs have
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a lesser abuse potential than II and an accepted medical use. Schedule I
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V drugs have low abuse potential and limited dependence liability.
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4.
What concept is considered when generic drugs are substituted for
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brand name drugs? mb mb




A) Bioavailability

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