Genetics and Genomics in Nursing and Health Care, 2nd Edition by
Theresa A Beery.
, Chapter`1:`DNA`Structure`and`Function
Multiple`Choice
Identify`the`choice`that`best`completes`the`statement`or`answers`the`question.
`` A. `1.` ` In`which`body`or`cell`area`are`most`genes`in`humans`located?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma`membrane
`` A. `2.` ` Which`condition`or`statement`exemplifies`the`concept`of`genomics`rather`than`genetics?
A. The`gene`for`insulin`is`located`on`chromosome`11`in`all`people.
B. Expression`of`any`single`gene`is`dependent`on`inheriting`two`alleles.
C. Sex-linked`recessive`disorders`affect`males`more`often`than`females.
D. One`allele`for`each`gene`is`inherited`from`the`mother,`and`one`is`inherited`from`the`f
ather.
`` A. `3.` ` What`is`the`purpose`of`phosphorous`in`a`DNA`strand?
A. Linking`the`nucleotides`into`a`strand
B. Holding`complementary`strands`together
C. Ensuring`that`a`purine`is`always`paired`with`a`pyrimidine
D. Preventing`the`separation`of`double-stranded`DNA`into`single-stranded`DNA
` A.
`4.` What`is`the`term`used`to`define`alternative`forms`of`a`gene`that`may`result`in`different`e
xpression`of`the`trait`coded`for`by`that`gene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
` D. `5.` What`percentage`of`bases`in`a`stretch`of`double-
stranded`DNA`that`contains`30%`guanine`(G)`bases`would`be`adenine`(A)?
A. 70%
B. 60%
C. 30%
D. 20%
` C.
`6.` What`is`the`term`used`to`describe`the`organized`picture`of`the`paired`chromosomes`w
ithin`a`cell`used`to`determine`whether`chromosome`numbers,`structures,`and`banding`patterns`ar
e`normal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
` D.
`7.` What`would`be`the`sequence`of`DNA`that`is`complementary`to`a`DNA`section`wit
h`the`base`sequence`of`GGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
,D. CCAGTTAGGAATC
, `` B. `8.` ` Which`of`these`complementary`base`pairs`form`the`strongest`or`“tightest”`association?
A. Adenine`and`thymine
B. Cytosine`and`guanine
C. Guanine`and`thymine
D. Cytosine`and`adenine
`` A ` 9.` ` What`activity`occurs`during`M`phase`of`the`cell`cycle?
A. The`cell`undergoes`cytokinesis.
B. Activity`stops,`and`the`cell`“sleeps.”
C. All`DNA`is`completely`replicated.
D. The`cell`greatly`increases`protein`synthesis.
`` B.` ` 10.` Which`chromosome`number`represents`the`euploid`state`for`normal`human`somatic`cells?
A. 44
B. 46
C. 47
D. 48
`` A.` ` 11.` How`does`the`proteome`differ`from`the`genome?
A. The`proteome`changes`in`response`to`intracellular`and`extracellular`signals.
B. The`genome`changes`in`response`to`intracellular`and`extracellular`signals.
C. The`proteome`is`stable`in`somatic`cells`and`unstable`in`germ`cells,`whereas`the`
genome`is`stable`in`both`somatic`cells`and`germ`cells.
D. The`genome`is`stable`in`somatic`cells`and`unstable`in`germ`cells,`whereas`the`
proteome`is`stable`in`both`somatic`cells`and`germ`cells.
`` C.` ` 12.` What`is`the`most`outstanding`feature`of`a`mature`haploid`cell?
A. It`is`usually`homozygous.
B. The`sex`chromosomes`are`missing.
C. Only`one`chromosome`of`each`pair`is`present.
D. DNA`synthesis`occurs`after`mitosis`instead`of`before.
`` D.` ` 13.` At`what`phase`of`the`cell`cycle`are`chromosomes`visible`as`separate`structures?
A. G1
B. G2
C. S
D. M
`` B.` ` 14.` Which`statement`about`the`cell`cycle`phase`of`G0`is`true?
A. Hyperplastic`growth`in`place`of`hypertrophic`growth
B. Performance`of`specific`differentiated`functions
C. Initiation`and`completion`of`nucleokinesis
D. Replication`of`DNA
`` B.` ` 15.` What`is`the`result`of`normal`DNA`replication?
A. Formation`of`two`new`daughter`cells
B. Formation`of`two`identical`sets`of`DNA
C. Disappearance`of`the`original`parent`cell
D. Activation`and`attachment`of`spindle`fibers