, THE IMMUNE SYSTEM, FOURTH EDITION CHAPTE
n n n n n
R 1: ELEMENTS OF THE IMMUNE SYSTEM
n n n n n n
AND THEIR ROLES IN DEFENSE
n n n n
© 2015 GARLAND SCIENCE
N N N
1–1 Then last n casesn of n smallpoxn weren reported n inn then .
a. 1950s
b. 1960s
c. 1970s
d. 1980s
e. 1990s.
1–2 Then first n linen of n defensen against n microorganismsn that n infect n then bodyn isn referred n ton as
.
a. opportunisticnimmunity
b. innaten immunity
c. adaptiven immunity
d. primaryn immunity
e. centraln immunity.
1–3 Whichn of n then followingn pairsn isn mismatched?
a. innaten immunity:n highlyn specialized n defenses
b. secondaryn immunen response:nimmunologicaln memory
c. hematopoiesis:n bonen marrow
d. phagocytosis:n uptaken and n killingn of n microbes
e. lymphocyten recirculation:n continuousn transport n betweenn blood n and n lymph.
1–4 Alln of n then followingn aren examplesn of n chemicaln barriersn of n innaten immunityn except n .
a. lacticn acid
b. normaln microbiota
c. lysozyme
d. fattyn acids
e. proteases.
1–5 Whenn effectorn lymphocytesn secreten ,n ann inflammatoryn responsen ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines.
1–6 Then thinn layern of n cellsn that n makesn upn then interiorn liningn of n then blood n vesselsn isn called n the
.
a. mucosa
1
,b. epithelium
c. endothelium
d. connectiventissue
e. lymphoid n tissue.
1–7 Identifyn then incorrect n statement n regardingn hematopoiesis.
a. Hematopoiesisn isn an continuousn processn that n occursn throughout n one’sn lifetime.
b. Then locationn forn hematopoiesisn differsn withn age.
c. Self n renewaln isn necessaryn ton replenishn then supplyn of n hematopoieticn stemn cells.
d. Most n hematopoiesisn occursn inn then bonen marrow n aftern birth.
e. Leukocytes,n but n not n erythrocytes,n must n gon throughn hematopoiesisn inn ordern ton develop.
1–8 Then progenitorsn of n macrophagesn aren .
a. megakaryocytes
b. dendriticn cells
c. monocytes
d. neutrophils
e. erythrocytes
f. Mn cells.
1–9 act n asn cellularn messengersn byn deliveringn degraded n pathogensn ton lymphoid n organs.
a. Plasman cells
b. Dendriticncells
c. Largen granularn lymphocytes
d. Mast n cells
e. Basophils.
1–10 Anothern namen forn an largen granularn lymphocyten isn an .
a. plasman cell
b. helpern Tn cell
c. monocyte
d. naturaln killern cell
e. eosinophil.
1–11 Effectorn cellsn that n secreten antibodiesn aren knownn asn .
a. naturaln killern cells
b. cytotoxicn Tn cells
c. helpern Tn cells
d. Mn cells
e. plasman cells
f. regulatoryn Tn cells.
1–12
Sphericaln regionsn inn lymphn nodesn containingn areasn that naren packed n denselyn withn
proliferatingn Bn cellsn aren called n .
a. efferent n vessels
b. germinaln centers
2
, c. red n pulpn zones
d. periarterialn lymphoid n sheaths
e. medullaryn sinuses.
1–13 Then isn (are)n then lymphoid n organ(s)n that n filter(s)n then blood.
a. spleen
b. tonsils
c. Peyer’sn patches
d. appendix
e. adenoids.
1–14 cellsn persist n longn aftern ann individualn hasn beenn vaccinated.
a. Neutrophil
b. Plasma
c. Memory
d. M
e. Mast.
1–15 Duringn ann infection,n aren mobilized n inn largen numbersn fromn then bonen marrow.
a. dendriticn cells
b. memoryn cells
c. macrophages
d. neutrophils
e. Bn cells.
1–16 Inn most n cases,n adaptiven immunen responsesn relyn onn then initialn activationn of n
inn secondaryn lymphoid n tissue:
a. macrophages
b. Tn cells
c. Bn cells
d. dendriticn cells
e. epithelium.
1–17 Alln of n then followingn statementsn aren characteristicn of n secondaryn immunen responsesn except
.
a. Secondaryn immunen responsesn aren activated n whenn primaryn immunen responsesn failn ton
completelyn eradicaten ann infection.
b. Secondaryn immunen responsesn aren restricted n ton adaptiven immunen responses.
c. Memoryn cellsn aren activated n rapidlyn duringn secondaryn immunen responses.
d. Secondaryn immunen responsesn aren ordersn of nmagnitudengreatern thannprimaryn immunen r
esponses.
e. Duringn an secondaryn immunen responsen ton anboosternvaccine,n it nisn possiblen tonexperiencen anp
rimaryn immunen responsen ton ann unrelated n vaccinen component n encountered n forn then first n time.
1–18
Identifyn thenfournclassesn of npathogensnthatnprovoken immunen responsesn inn ourn bodiesn andng
iven ann examplen of n each.
3
n n n n n
R 1: ELEMENTS OF THE IMMUNE SYSTEM
n n n n n n
AND THEIR ROLES IN DEFENSE
n n n n
© 2015 GARLAND SCIENCE
N N N
1–1 Then last n casesn of n smallpoxn weren reported n inn then .
a. 1950s
b. 1960s
c. 1970s
d. 1980s
e. 1990s.
1–2 Then first n linen of n defensen against n microorganismsn that n infect n then bodyn isn referred n ton as
.
a. opportunisticnimmunity
b. innaten immunity
c. adaptiven immunity
d. primaryn immunity
e. centraln immunity.
1–3 Whichn of n then followingn pairsn isn mismatched?
a. innaten immunity:n highlyn specialized n defenses
b. secondaryn immunen response:nimmunologicaln memory
c. hematopoiesis:n bonen marrow
d. phagocytosis:n uptaken and n killingn of n microbes
e. lymphocyten recirculation:n continuousn transport n betweenn blood n and n lymph.
1–4 Alln of n then followingn aren examplesn of n chemicaln barriersn of n innaten immunityn except n .
a. lacticn acid
b. normaln microbiota
c. lysozyme
d. fattyn acids
e. proteases.
1–5 Whenn effectorn lymphocytesn secreten ,n ann inflammatoryn responsen ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines.
1–6 Then thinn layern of n cellsn that n makesn upn then interiorn liningn of n then blood n vesselsn isn called n the
.
a. mucosa
1
,b. epithelium
c. endothelium
d. connectiventissue
e. lymphoid n tissue.
1–7 Identifyn then incorrect n statement n regardingn hematopoiesis.
a. Hematopoiesisn isn an continuousn processn that n occursn throughout n one’sn lifetime.
b. Then locationn forn hematopoiesisn differsn withn age.
c. Self n renewaln isn necessaryn ton replenishn then supplyn of n hematopoieticn stemn cells.
d. Most n hematopoiesisn occursn inn then bonen marrow n aftern birth.
e. Leukocytes,n but n not n erythrocytes,n must n gon throughn hematopoiesisn inn ordern ton develop.
1–8 Then progenitorsn of n macrophagesn aren .
a. megakaryocytes
b. dendriticn cells
c. monocytes
d. neutrophils
e. erythrocytes
f. Mn cells.
1–9 act n asn cellularn messengersn byn deliveringn degraded n pathogensn ton lymphoid n organs.
a. Plasman cells
b. Dendriticncells
c. Largen granularn lymphocytes
d. Mast n cells
e. Basophils.
1–10 Anothern namen forn an largen granularn lymphocyten isn an .
a. plasman cell
b. helpern Tn cell
c. monocyte
d. naturaln killern cell
e. eosinophil.
1–11 Effectorn cellsn that n secreten antibodiesn aren knownn asn .
a. naturaln killern cells
b. cytotoxicn Tn cells
c. helpern Tn cells
d. Mn cells
e. plasman cells
f. regulatoryn Tn cells.
1–12
Sphericaln regionsn inn lymphn nodesn containingn areasn that naren packed n denselyn withn
proliferatingn Bn cellsn aren called n .
a. efferent n vessels
b. germinaln centers
2
, c. red n pulpn zones
d. periarterialn lymphoid n sheaths
e. medullaryn sinuses.
1–13 Then isn (are)n then lymphoid n organ(s)n that n filter(s)n then blood.
a. spleen
b. tonsils
c. Peyer’sn patches
d. appendix
e. adenoids.
1–14 cellsn persist n longn aftern ann individualn hasn beenn vaccinated.
a. Neutrophil
b. Plasma
c. Memory
d. M
e. Mast.
1–15 Duringn ann infection,n aren mobilized n inn largen numbersn fromn then bonen marrow.
a. dendriticn cells
b. memoryn cells
c. macrophages
d. neutrophils
e. Bn cells.
1–16 Inn most n cases,n adaptiven immunen responsesn relyn onn then initialn activationn of n
inn secondaryn lymphoid n tissue:
a. macrophages
b. Tn cells
c. Bn cells
d. dendriticn cells
e. epithelium.
1–17 Alln of n then followingn statementsn aren characteristicn of n secondaryn immunen responsesn except
.
a. Secondaryn immunen responsesn aren activated n whenn primaryn immunen responsesn failn ton
completelyn eradicaten ann infection.
b. Secondaryn immunen responsesn aren restricted n ton adaptiven immunen responses.
c. Memoryn cellsn aren activated n rapidlyn duringn secondaryn immunen responses.
d. Secondaryn immunen responsesn aren ordersn of nmagnitudengreatern thannprimaryn immunen r
esponses.
e. Duringn an secondaryn immunen responsen ton anboosternvaccine,n it nisn possiblen tonexperiencen anp
rimaryn immunen responsen ton ann unrelated n vaccinen component n encountered n forn then first n time.
1–18
Identifyn thenfournclassesn of npathogensnthatnprovoken immunen responsesn inn ourn bodiesn andng
iven ann examplen of n each.
3
