NCLEX-RN PHARMACOLOGY REVIEW
QUESTIONS AND ANSWERS 100%
SOLVED!
Acetaminophen
(Tylenol) - ANSWERSTherapeutic: 1-30 mcg/ml
Toxic: >200 mcg/ml
Contraindicated in:
Liver disease
Side Effects of Toxicity:
Hepatic Necrosis
Alcohol
(Ethanol) - ANSWERSTherapeutic Level: 100 mcg/ml
Toxic: >400 mcg/ml
Amikacin - ANSWERSTroughs Peaks
5 mcg/ml 35 mcg/ml
Amitriptyline
(Elavil) - ANSWERSTherapeutic: 120-250 mcg/ml
Toxic: >500 mcg/ml
Contraindicated in: Narrow-angle glaucoma and potential fatal reactions when used with
MAO inhibitors
Side Effects of Toxicity:
Drowsiness, sedation, lethary, fatigue, dry mouth and eyes, blurred vision, hypotension,
and tachycardia.
Caution patients to use a sun screen.
Therapeutic effects within 2 to 6 weeks of initiating therapy.
Carbamazepine
(Tegretol) - ANSWERSTherapeutic: 8-12 mcg/ml
Toxic: >15 mcg/ml
Contraindicated in:
Bone marrow depression
Side Effects of Toxicity:
Drowsiness, dizziness, and ataxia.
Caution patients to use a sun screen and to carry a medical alert card.
Chlordiazepoxide
(Librium) - ANSWERSTherapeutic: 700-1000 mcg/ml
Toxic: >5000 mcg/ml
Contraindicated in:
, Comatose patients with CNS depression, narrow-angle glaucoma
Side Effects of Toxicity:
Drowsiness and dizziness.
Alcohol Withdrawal Treatment: Assess patients for signs and symptoms of delirium
tremors (DTs).
Desopyramide
(Norpace) - ANSWERSTherapeutic: Variable
Toxic: >7 mcg/ml
Contraindicated in:
Cardiogenic shock, 2nd and 3rd degree heart blocks, sick sinus syndrome
Side Effects of Toxicity:
Signs and symptoms of congestive heart failure.
Diazepam
(Valium) - ANSWERSTherapeutic: 100-1000 mcg/ml
Toxic: >5000 mcg/ml
Contraindicated in:
Comatose patients with CNS depression, narrow-angle glaucoma
Side Effects of Toxicity:
Sedation with ataxia, dizziness, and slurred speech.
Therapeutic effects within 1 to 2 weeks of initiating therapy.
Digitoxin - ANSWERSTherapeutic: 20-35 ng/ml
Toxic: >45 ng/ml
Contraindicated in:
Uncontrolled ventricular arrhythmias, AV block
Side Effects of Toxicity:
Abdominal pain, anorexia, nausea, vomiting, visual disturbances, bradycardia, and
other arrhythmias.
Digoxin - ANSWERSTherapeutic: 0.8-1.5 mcg/ml
Toxic: >2 mcg/ml
Contraindicated in:
Uncontrolled ventricular arrhythmias, AV block
Side Effects of Toxicity:
Abdominal pain, anorexia, nausea, vomiting, visual disturbances, bradycardia, and
other arrhythmias.
Doxepin - ANSWERSTherapeutic: 30-150 mcg/ml
Toxic: >500 mcg/ml
Contraindicated in:
Narrow-angle glaucoma
Side Effects of Toxicity:
Sedation, fatigue, blurred vision, hypotension, dry mouth, and constipation.
Caution patients to use a sun screen.
QUESTIONS AND ANSWERS 100%
SOLVED!
Acetaminophen
(Tylenol) - ANSWERSTherapeutic: 1-30 mcg/ml
Toxic: >200 mcg/ml
Contraindicated in:
Liver disease
Side Effects of Toxicity:
Hepatic Necrosis
Alcohol
(Ethanol) - ANSWERSTherapeutic Level: 100 mcg/ml
Toxic: >400 mcg/ml
Amikacin - ANSWERSTroughs Peaks
5 mcg/ml 35 mcg/ml
Amitriptyline
(Elavil) - ANSWERSTherapeutic: 120-250 mcg/ml
Toxic: >500 mcg/ml
Contraindicated in: Narrow-angle glaucoma and potential fatal reactions when used with
MAO inhibitors
Side Effects of Toxicity:
Drowsiness, sedation, lethary, fatigue, dry mouth and eyes, blurred vision, hypotension,
and tachycardia.
Caution patients to use a sun screen.
Therapeutic effects within 2 to 6 weeks of initiating therapy.
Carbamazepine
(Tegretol) - ANSWERSTherapeutic: 8-12 mcg/ml
Toxic: >15 mcg/ml
Contraindicated in:
Bone marrow depression
Side Effects of Toxicity:
Drowsiness, dizziness, and ataxia.
Caution patients to use a sun screen and to carry a medical alert card.
Chlordiazepoxide
(Librium) - ANSWERSTherapeutic: 700-1000 mcg/ml
Toxic: >5000 mcg/ml
Contraindicated in:
, Comatose patients with CNS depression, narrow-angle glaucoma
Side Effects of Toxicity:
Drowsiness and dizziness.
Alcohol Withdrawal Treatment: Assess patients for signs and symptoms of delirium
tremors (DTs).
Desopyramide
(Norpace) - ANSWERSTherapeutic: Variable
Toxic: >7 mcg/ml
Contraindicated in:
Cardiogenic shock, 2nd and 3rd degree heart blocks, sick sinus syndrome
Side Effects of Toxicity:
Signs and symptoms of congestive heart failure.
Diazepam
(Valium) - ANSWERSTherapeutic: 100-1000 mcg/ml
Toxic: >5000 mcg/ml
Contraindicated in:
Comatose patients with CNS depression, narrow-angle glaucoma
Side Effects of Toxicity:
Sedation with ataxia, dizziness, and slurred speech.
Therapeutic effects within 1 to 2 weeks of initiating therapy.
Digitoxin - ANSWERSTherapeutic: 20-35 ng/ml
Toxic: >45 ng/ml
Contraindicated in:
Uncontrolled ventricular arrhythmias, AV block
Side Effects of Toxicity:
Abdominal pain, anorexia, nausea, vomiting, visual disturbances, bradycardia, and
other arrhythmias.
Digoxin - ANSWERSTherapeutic: 0.8-1.5 mcg/ml
Toxic: >2 mcg/ml
Contraindicated in:
Uncontrolled ventricular arrhythmias, AV block
Side Effects of Toxicity:
Abdominal pain, anorexia, nausea, vomiting, visual disturbances, bradycardia, and
other arrhythmias.
Doxepin - ANSWERSTherapeutic: 30-150 mcg/ml
Toxic: >500 mcg/ml
Contraindicated in:
Narrow-angle glaucoma
Side Effects of Toxicity:
Sedation, fatigue, blurred vision, hypotension, dry mouth, and constipation.
Caution patients to use a sun screen.
