NURS 6630
PSYCHOPHARMACOLOGY
MIDTERM EXAM TEST BANK
Purplesanswerssweresmarkedsincorrect.s Redsanswerssweresmarkedscorrect.
QUESTIONs1
1.
Asnoncompliantspatientsstates,s"Whysdosyouswantsmestosputsthisspoisonsinsmysbody?"sId
entifysthesbestsresponsesmadesbysthespsychiatric-mentalshealthsnursespractitioners(PMHNP).sA.
"Youshavestostakesyoursmedicationstosbecomesstable."sB.
"Mostsmedicationsswillsincreasesthesnumbersofsneurotransmitterssthatsyousalreadyshavesinsth
esbrain."sC.
"Mostsmedicationssusedsinstreatmentsareseithersincreasingsorsdecreasingsneurotransmitt
erssthatsyoursbodysalreadyshas."sD.
"Whysdosyousbelievesthatsyoursmedicationsisspoison?"s Isreceiveds0/1sforsthissanswer??s1spointss
QUESTIONs2
1.
Whichsstatementsaboutsneurotransmitterssandsmedicationssisstrue?s Myscorrectsanswers
wassseveralspsychiatricsmedssweresdevelopedsaftersdiscoverysofsendogenoussneurotransmitt
ers.s (Thesanswerswordingsissdifferent.sA.
Naturalsneurotransmittersssuchsassendorphinsshavesbeensdiscoveredsaftersthesdevelopmentsofs
medications.sB.
Somesmedicationssweresdevelopedsaftersthesdiscoverysandsknownsactionsofsthesneurotransmit
terssinsthesbrain.sC.
Neurotransmitterssreceivesmessagessfromsmostsmedications.sD.
Thes neurotransmitters serotonins iss directlys linkeds tos depression.s Followings thiss discovery,s thes
antidepressantsProzacswassdeveloped.
,1spoints
QUESTIONs3
1.
Whensansunstablespatientsasksswhysitsissnecessarystosaddsmedicationsstoshisscurrents
regimen,sthesPMHNP'ssbestsresponseswouldsbe:sA.
"Insansextremescasessuchsassyours,smoresthansonesmedicationsissoftensneeded."sB.s"Du
estosthesineffectivenesssofsyourscurrentsmedication,swesneedstostryssomethingselsestha
tscanspossiblyspotentiatesitsseffects.sC.
"Medicationssaresoftensspecificstosthesneurotransmitter(s)stheysaresaffectingsand,sduestosmorest
hansonesneurotransmittersinvolvement,sitsissoftensnecessarystosusesmoresthansonesmedicationsto
s improvessymptoms."sD.
"Isunderstandsyoursconcern.sWescansdiscontinuesyourscurrentsmedicationsandsswitchstosasdiffer
entsonesthatsmaysbettersmanagesyourssymptoms."
1spoints
QUESTIONs4s ?
1.s s Duringsgenesexpression,swhatsmustsoccurspriorstosasgenesbeingsexpressed?sA.sT
ranscriptionsfactorsmustsbindstosthesregulatorysregionswithinsthescell'ssnucleus.sB.s
RNAsmustsbesconvertedstosmRNA.sC.
Thescodingsregionsmustsseparatesfromsthesregulatorysregion.s Thississwrongs
D.
RNAspolymerasesmustsinhibitsthesprocesssofschangingsRNAstosmRNA.
1spointss QUESTIONs5
1.
Whilesgenesshavespotentialstosmodifysbehavior,sbehaviorscansalsosmodifysgenes.sHowsdos
genessimpactsthissprocess?sA.
Genessimpactsneuronsfunctioningsdirectly.s
B.
Changessmadestosproteinssleadstoschangessinsbehavior.sC.s
Neuronssaresablestosimpactsproteinssynthesis.sD.
GenessimpactsthesDNAsofsascell,sleadingstoschangessinsbehavior.
1spointss QUESTIONs6
1.
Thoughsmedicationsshavesthesabilitystostargetsneurotransmitterssinsthessynapse,sitsissnots
alwayssnecessary.sThesPMHNPsunderstandssthatsthississbecause:sA.
Neurotransmissionsthatsoccurssviasthesaxonsallowssforstransportsofsasneurot
ransmitter.sB.
Activestransportsissasdifferentstypesofsenergysthatsallowssthestransportsofscertainsneurotransmi
tters.sC.
Neurotransmittersscansspreadsbysdiffusion.sD.
,Thespostsynapticsneuronscansreleasesthesneurotransmitter.
1spointss QUESTIONs7
1. WhysissthescytochromesP450senzymessystemsofssignificancestosthes
PMHNP?
A.
Theskidneyssplaysasroleswithsexcretionsofsthesmedication,sandsifsaspatientshasskidneysdamage,st
hesdosesmustsbesincreasedstosbeseffective.sB.
Thesbioavailabilitysofsthesmedicationsaftersitspassessthroughsthesstomachsandsliverscansbesalter
ed.s CorrectsanswersC.
Thesmedication'sschemicalscompositionschangesswhensitscomessinscontactswithsthesacidsinst
hesstomach.sD.
ThesCYPsenzymessystemsissassteadysandspredictablesprocesssthatsprescriberssmustsunderstandst
ostreatsconditionsseffectively.
1spointss QUESTIONs8
1.
ItsissimportantsforsthesPMHNPstosrecognizesdifferencessinspharmacokineticsstossafelysp
rescribesandsmonitorsmedications.sWhichsofsthesfollowingsstatementssdoessthescompetentsP
MHNPsidentifysasstrue?sA.
Abouts1soutsofs5sAsianssrequiresslower-than-
normalsdosessofssomesantidepressantssandsantipsychotics.sB.
Thestermspolymorphicsrefersstosthesbody'ssabilitystosbreaksasmedicationsdownsseveralsways,san
dsthisspatientsmaysrequireshighersdosessofscertainsantidepressantssandsantipsychotics.sC.sAbou
ts1soutsofs30sCaucasianssrequiresslowersdosessofssomesantidepressantssandsantipsychotics.sD.
Mostsenzymespathwayssdosnotshavesinteractionssbetweensthesnewersmedications.s1spoi
nts
QUESTIONs9
1. AssitsrelatesstosG-
proteinslinkedsreceptors,swhatsdoessthesPMHNPsunderstandsaboutsmedicationssth
atsaresusedsinspractice?sA.
MostsmedicationssthatsactsonsG-proteinslinkedsreceptorsshavesantagonisticstraits.sB.
Thesmajoritysofsmedicationssusedsinspracticesaresfullsagonistssandsaresusedstosstimulatesthesbo
dy'ssnaturalsneurotransmitters.sC.
Mostsmedicationssactsasspartialsagonistssbecausestheysallowsthesbodystosusesonlyswhatsissneed
ed.sD.
Medicationssusedsinspracticesmaysactsassinversesagonistssifsthesdosagesisstooshigh.s1spoints
, QUESTIONs10
1. ThesPMHNPsissconsideringsprescribingsas49-year-
oldsmalesclozapines(Clozaril)stostreatshissschizophreniasandssuicidalsideations.sThesPMHNPsissawar
esthatswhichsfactorsmaysimpactsthesdosesneededstoseffectivelystreatshisscondition:sA.
Thespatientssmokesscigarettes.
Thississcorrect!sB.
s Thespatientshasshypertension.sC.
Thespatientshasschronicskidneysdisease,sstages2.sD.s
Thespatientsdrinkssascupsofscoffeesasday.
1spointss QUESTIONs11
1.
Aspatientsissdiagnosedswithsbipolarsdisordersandsisscurrentlystakingscarbamazepines(Tegr
etol),saripiprazoles(Abilify),sandsmelatonin.sThesPMHNPshassjustswrittensansorderstosdiscontin
uesthescarbamazepines(Tegretol)sforsdruginducedsthrombocytopenia.sThesPMHNPsissawaresth
atshissnextsbestsactionsissto:sA.
AlertsstaffstospossiblesseizuressB.
Writesansordersforsasdifferentsmoodsstabilizer
ForssomesreasonsIsgots0/1spointssforsthis??
s C.
Decreasesthesamountsprescribedsforsaripiprazoles(Abilify)sD.
Explainstosthespatientsthatsitswillsbesmoresdifficultstoscontrolshisstemper
1spointss QUESTIONs12
1.
Aspatientsrecentlystransferredsfollowingsassuicidesattemptshassashistorysofsschizophrenia,sd
epression,sandsfibromyalgia.sHesisscurrentlystakingsAmitriptylines(Elavil),sLisinopril,saspirin,sandsfl
uoxetines(Prozac).sWhichsissthesbestsactionsforsthesPMHNPstostakesforsthisspatient?sA.
ReviewsAmitriptylines(Elavil)slevels CorrectsanswersB.sOrde
rsasliversfunctionstestsC.
Checksthespatient'ssbloodspressuresandspulsesD.sOr
dersasstatsplateletscount
1spointss QUESTIONs13
1.s s Aspatientswithsschizophreniasissgivensansinversesagoniststhatsactssonsthesreceptors5HTsandsn
eurotransmittersserotonin.sWhatsissthesrationalesforsprescribingsasmedicationssuchsassthis?sA.sT
ospromotesthesavailabilitysofsserotoninsB.
TosdecreasesserotoninsC.
TosindirectlysincreasesthesamountsofsdopaminesinsthesbodysD.s
Toshelpsdecreasesthesamountsofsserotoninsandsdopamine
PSYCHOPHARMACOLOGY
MIDTERM EXAM TEST BANK
Purplesanswerssweresmarkedsincorrect.s Redsanswerssweresmarkedscorrect.
QUESTIONs1
1.
Asnoncompliantspatientsstates,s"Whysdosyouswantsmestosputsthisspoisonsinsmysbody?"sId
entifysthesbestsresponsesmadesbysthespsychiatric-mentalshealthsnursespractitioners(PMHNP).sA.
"Youshavestostakesyoursmedicationstosbecomesstable."sB.
"Mostsmedicationsswillsincreasesthesnumbersofsneurotransmitterssthatsyousalreadyshavesinsth
esbrain."sC.
"Mostsmedicationssusedsinstreatmentsareseithersincreasingsorsdecreasingsneurotransmitt
erssthatsyoursbodysalreadyshas."sD.
"Whysdosyousbelievesthatsyoursmedicationsisspoison?"s Isreceiveds0/1sforsthissanswer??s1spointss
QUESTIONs2
1.
Whichsstatementsaboutsneurotransmitterssandsmedicationssisstrue?s Myscorrectsanswers
wassseveralspsychiatricsmedssweresdevelopedsaftersdiscoverysofsendogenoussneurotransmitt
ers.s (Thesanswerswordingsissdifferent.sA.
Naturalsneurotransmittersssuchsassendorphinsshavesbeensdiscoveredsaftersthesdevelopmentsofs
medications.sB.
Somesmedicationssweresdevelopedsaftersthesdiscoverysandsknownsactionsofsthesneurotransmit
terssinsthesbrain.sC.
Neurotransmitterssreceivesmessagessfromsmostsmedications.sD.
Thes neurotransmitters serotonins iss directlys linkeds tos depression.s Followings thiss discovery,s thes
antidepressantsProzacswassdeveloped.
,1spoints
QUESTIONs3
1.
Whensansunstablespatientsasksswhysitsissnecessarystosaddsmedicationsstoshisscurrents
regimen,sthesPMHNP'ssbestsresponseswouldsbe:sA.
"Insansextremescasessuchsassyours,smoresthansonesmedicationsissoftensneeded."sB.s"Du
estosthesineffectivenesssofsyourscurrentsmedication,swesneedstostryssomethingselsestha
tscanspossiblyspotentiatesitsseffects.sC.
"Medicationssaresoftensspecificstosthesneurotransmitter(s)stheysaresaffectingsand,sduestosmorest
hansonesneurotransmittersinvolvement,sitsissoftensnecessarystosusesmoresthansonesmedicationsto
s improvessymptoms."sD.
"Isunderstandsyoursconcern.sWescansdiscontinuesyourscurrentsmedicationsandsswitchstosasdiffer
entsonesthatsmaysbettersmanagesyourssymptoms."
1spoints
QUESTIONs4s ?
1.s s Duringsgenesexpression,swhatsmustsoccurspriorstosasgenesbeingsexpressed?sA.sT
ranscriptionsfactorsmustsbindstosthesregulatorysregionswithinsthescell'ssnucleus.sB.s
RNAsmustsbesconvertedstosmRNA.sC.
Thescodingsregionsmustsseparatesfromsthesregulatorysregion.s Thississwrongs
D.
RNAspolymerasesmustsinhibitsthesprocesssofschangingsRNAstosmRNA.
1spointss QUESTIONs5
1.
Whilesgenesshavespotentialstosmodifysbehavior,sbehaviorscansalsosmodifysgenes.sHowsdos
genessimpactsthissprocess?sA.
Genessimpactsneuronsfunctioningsdirectly.s
B.
Changessmadestosproteinssleadstoschangessinsbehavior.sC.s
Neuronssaresablestosimpactsproteinssynthesis.sD.
GenessimpactsthesDNAsofsascell,sleadingstoschangessinsbehavior.
1spointss QUESTIONs6
1.
Thoughsmedicationsshavesthesabilitystostargetsneurotransmitterssinsthessynapse,sitsissnots
alwayssnecessary.sThesPMHNPsunderstandssthatsthississbecause:sA.
Neurotransmissionsthatsoccurssviasthesaxonsallowssforstransportsofsasneurot
ransmitter.sB.
Activestransportsissasdifferentstypesofsenergysthatsallowssthestransportsofscertainsneurotransmi
tters.sC.
Neurotransmittersscansspreadsbysdiffusion.sD.
,Thespostsynapticsneuronscansreleasesthesneurotransmitter.
1spointss QUESTIONs7
1. WhysissthescytochromesP450senzymessystemsofssignificancestosthes
PMHNP?
A.
Theskidneyssplaysasroleswithsexcretionsofsthesmedication,sandsifsaspatientshasskidneysdamage,st
hesdosesmustsbesincreasedstosbeseffective.sB.
Thesbioavailabilitysofsthesmedicationsaftersitspassessthroughsthesstomachsandsliverscansbesalter
ed.s CorrectsanswersC.
Thesmedication'sschemicalscompositionschangesswhensitscomessinscontactswithsthesacidsinst
hesstomach.sD.
ThesCYPsenzymessystemsissassteadysandspredictablesprocesssthatsprescriberssmustsunderstandst
ostreatsconditionsseffectively.
1spointss QUESTIONs8
1.
ItsissimportantsforsthesPMHNPstosrecognizesdifferencessinspharmacokineticsstossafelysp
rescribesandsmonitorsmedications.sWhichsofsthesfollowingsstatementssdoessthescompetentsP
MHNPsidentifysasstrue?sA.
Abouts1soutsofs5sAsianssrequiresslower-than-
normalsdosessofssomesantidepressantssandsantipsychotics.sB.
Thestermspolymorphicsrefersstosthesbody'ssabilitystosbreaksasmedicationsdownsseveralsways,san
dsthisspatientsmaysrequireshighersdosessofscertainsantidepressantssandsantipsychotics.sC.sAbou
ts1soutsofs30sCaucasianssrequiresslowersdosessofssomesantidepressantssandsantipsychotics.sD.
Mostsenzymespathwayssdosnotshavesinteractionssbetweensthesnewersmedications.s1spoi
nts
QUESTIONs9
1. AssitsrelatesstosG-
proteinslinkedsreceptors,swhatsdoessthesPMHNPsunderstandsaboutsmedicationssth
atsaresusedsinspractice?sA.
MostsmedicationssthatsactsonsG-proteinslinkedsreceptorsshavesantagonisticstraits.sB.
Thesmajoritysofsmedicationssusedsinspracticesaresfullsagonistssandsaresusedstosstimulatesthesbo
dy'ssnaturalsneurotransmitters.sC.
Mostsmedicationssactsasspartialsagonistssbecausestheysallowsthesbodystosusesonlyswhatsissneed
ed.sD.
Medicationssusedsinspracticesmaysactsassinversesagonistssifsthesdosagesisstooshigh.s1spoints
, QUESTIONs10
1. ThesPMHNPsissconsideringsprescribingsas49-year-
oldsmalesclozapines(Clozaril)stostreatshissschizophreniasandssuicidalsideations.sThesPMHNPsissawar
esthatswhichsfactorsmaysimpactsthesdosesneededstoseffectivelystreatshisscondition:sA.
Thespatientssmokesscigarettes.
Thississcorrect!sB.
s Thespatientshasshypertension.sC.
Thespatientshasschronicskidneysdisease,sstages2.sD.s
Thespatientsdrinkssascupsofscoffeesasday.
1spointss QUESTIONs11
1.
Aspatientsissdiagnosedswithsbipolarsdisordersandsisscurrentlystakingscarbamazepines(Tegr
etol),saripiprazoles(Abilify),sandsmelatonin.sThesPMHNPshassjustswrittensansorderstosdiscontin
uesthescarbamazepines(Tegretol)sforsdruginducedsthrombocytopenia.sThesPMHNPsissawaresth
atshissnextsbestsactionsissto:sA.
AlertsstaffstospossiblesseizuressB.
Writesansordersforsasdifferentsmoodsstabilizer
ForssomesreasonsIsgots0/1spointssforsthis??
s C.
Decreasesthesamountsprescribedsforsaripiprazoles(Abilify)sD.
Explainstosthespatientsthatsitswillsbesmoresdifficultstoscontrolshisstemper
1spointss QUESTIONs12
1.
Aspatientsrecentlystransferredsfollowingsassuicidesattemptshassashistorysofsschizophrenia,sd
epression,sandsfibromyalgia.sHesisscurrentlystakingsAmitriptylines(Elavil),sLisinopril,saspirin,sandsfl
uoxetines(Prozac).sWhichsissthesbestsactionsforsthesPMHNPstostakesforsthisspatient?sA.
ReviewsAmitriptylines(Elavil)slevels CorrectsanswersB.sOrde
rsasliversfunctionstestsC.
Checksthespatient'ssbloodspressuresandspulsesD.sOr
dersasstatsplateletscount
1spointss QUESTIONs13
1.s s Aspatientswithsschizophreniasissgivensansinversesagoniststhatsactssonsthesreceptors5HTsandsn
eurotransmittersserotonin.sWhatsissthesrationalesforsprescribingsasmedicationssuchsassthis?sA.sT
ospromotesthesavailabilitysofsserotoninsB.
TosdecreasesserotoninsC.
TosindirectlysincreasesthesamountsofsdopaminesinsthesbodysD.s
Toshelpsdecreasesthesamountsofsserotoninsandsdopamine
