Drugs that can cause hyponatremia ✔️Ans - thiazide diuretics,
carbamazepine/oxcarbazepine, SSRI's, TCAs
hypokalemia/hyperkalemia effect on ECG ✔️Ans - Hypokalemia:
flattened T waves, elevated U wave
Hyperkalemia: Narrowed T waves, widened QRS
Overfeeding complications ✔️Ans - hepatic steatosis, hypercapnia (resp
acidosis), hyperglycemia, azotemia
Calorie goals ✔️Ans - 25-35 kcal /kg for normal weight
11-14 kcal/kg for obese
*intentional underfeeding (60-70% kcal goal) of critically ill patients while
keeping protein 90-100% showed a mortality benefit
Protein goals ✔️Ans - 0.8-1 g/kg/da for maintenance
1.5 g/kg/day for stressed patients
2.5 g/kg/day for CRRT
2-2.5 g/kg IBW/day for obese patients
3 g/kg/day in burn patients
MAP formula ✔️Ans - [SBP+(2DBP)]/3
Effects of TTM (therapeutic hypothermia) ✔️Ans - reduced drug
clearance, bleeding, increased water excretion, bradycardia, hyperglycemia,
hyokalemia, hypomagnesemia, hypophosphatemia
Starting rate and max rate of propofol ✔️Ans - Starting rate: 5
mcg/kg/minute
Max rate: 80 mcg/kg/minute
*above this can cause PRIS
Starting rate and max rate of Precedex ✔️Ans - Starting rate: 0.2
mcg/kg/hour
Max rate: 1.5 mcg/kg/hour
, BP goal in ICH ✔️Ans - <140
Drugs used in ICH ✔️Ans - aminocaproic acid 4-5 g load followed by
1g/hour
nimodipine 60 mg q4h x 21 days in SAH for vasospasm
Normal NADIR after chemo ✔️Ans - 10-14 days recovering at 3-4 weeks
*mitomycin, decitabine, azacitidine, bleomycin, vincristine, carmustine
have delayed NADIR 28-42 days recovering at 6-8 weeks
Chemos that should be adjusted for renal function ✔️Ans -
methotrexate, carbo, cisplatin, etoposide, bleomycin, topotecan,
capecitabine, lenalidomide
Chemos that should be adjusted for hepatic function ✔️Ans -
anthracyclines, vinca alkaloids, taxanes, methotrexate
CURB-65 ✔️Ans - 1) Confusion
2) BUN>19
3) RR>30
4) BP<90/60
5) 65yo
One or less indicates patient can be treated outpatient, >1 =hospitalization
MRSA risk factors ✔️Ans - prior respiratory MRSA
hospitalization/parenteral abx given in last 90 days
When are 2 antipseudomonals indicated in pneumonia ✔️Ans - VAP:
risk factors for MDR organisms= IV abx in past 90 days, hospitalization of 5
days or more, septic shock, ARDS, acute renal replacement therapy before
VAP
HAP: IV abx in the past 90 days, high risk of mortality including being on a
ventilator.
pseudomonas risk factors ✔️Ans - IV abx within last 90 days??
Brand: Seropehen
Generic: clomiphene ✔️Ans - first line for infertility, used in PCOS for
fertility improvement