NURS 663 Test 4 – Questions & Correct Answers
substance use disorder specifier criteria ✔️Ans - Mild: 2-3 symptoms
Moderate: 4-5 symtpoms
Severe: >6 symptoms
DSM for substance use disorder ✔️Ans - over 12 months
use increase amount
persistant desire or can't cut down
lots of time spent on substance
craving
failure to fill roles
social/personal problems
activities given up/reduced
use when physically hazardous
continue despite problem
tolerence
withdrawal
abuse ✔️Ans - use of any drug in a manner that deviates from approved
social or medial patterns
cross tolerence ✔️Ans - the ability of one drug to be substituted for another
each usually producing the same effects ex: diazepam and barbituates
misuse ✔️Ans - similar to abuse, but usually applies to drugs prescribed by
physicians that are not used properly
tolerence ✔️Ans - after repeated administration, a given dose of a drug
produces a decreased effect or larger doses must be administered to obtain
the effect observed with the original dose
withdrawal ✔️Ans - a substance specific syndrome that occurs after
stopping or reducing the amount of drug or substance that has been used
regularly over a prolonged period
acamprosate; what, side effects, dose ✔️Ans - what: alcohol relapse
prevention; "artificial alcohol" decreases glutamate and increases GABA
, side effects: anxiety, depression, diarrhea, decreased libido, flu like
dose: 666mg TID
must be abstinent from etoh first
buprenorphine; moa, who can use ✔️Ans - MOA: partial opioid agonist,
prevents pleasurable effects, is a opiate analgesic
who: pregnant okay, must be in mild withdrawal to start
buprenorphine dosing ✔️Ans - must be in withdrawal to start
SL 8-32mg/d
which medications are in Suboxone ✔️Ans - buprenorphine and naloxone
buproprion; dosing ✔️Ans - for smoking cessation: begin 7-14d before stop
date; 150mg SR in am x6 days then increase to 150mg SR BID
tx for 7-9 weeks
chlordiazepoxide; MOA, what for, dosing ✔️Ans - MOA: enhances GABA
for acute alcohol withdrawal
50-100mg injectable every 2hrs
clonidine; MOA ✔️Ans - alpha 2 receptors
clonidine for opiate withdrawal ✔️Ans - blocks autonomic symptoms;
palpitations, sweating
clonidine for etoh withdrawal ✔️Ans - decrease bp, decrease HR, tremors
disulfiram; MOA ✔️Ans - inhibits acetalhydine and leads to buildup of
acetaldehyde and causes immediate hangover effect after alcohol
consumption
disulfiram dosing ✔️Ans - 250-500mg/d
flumazenil; MOA, use, dosing, se ✔️Ans - MOA: blocks benzo receptors at
GABA
use: benzo antidote
dosing: 0.4mg-3mg
se: dizzy, sweating, seizures, death
substance use disorder specifier criteria ✔️Ans - Mild: 2-3 symptoms
Moderate: 4-5 symtpoms
Severe: >6 symptoms
DSM for substance use disorder ✔️Ans - over 12 months
use increase amount
persistant desire or can't cut down
lots of time spent on substance
craving
failure to fill roles
social/personal problems
activities given up/reduced
use when physically hazardous
continue despite problem
tolerence
withdrawal
abuse ✔️Ans - use of any drug in a manner that deviates from approved
social or medial patterns
cross tolerence ✔️Ans - the ability of one drug to be substituted for another
each usually producing the same effects ex: diazepam and barbituates
misuse ✔️Ans - similar to abuse, but usually applies to drugs prescribed by
physicians that are not used properly
tolerence ✔️Ans - after repeated administration, a given dose of a drug
produces a decreased effect or larger doses must be administered to obtain
the effect observed with the original dose
withdrawal ✔️Ans - a substance specific syndrome that occurs after
stopping or reducing the amount of drug or substance that has been used
regularly over a prolonged period
acamprosate; what, side effects, dose ✔️Ans - what: alcohol relapse
prevention; "artificial alcohol" decreases glutamate and increases GABA
, side effects: anxiety, depression, diarrhea, decreased libido, flu like
dose: 666mg TID
must be abstinent from etoh first
buprenorphine; moa, who can use ✔️Ans - MOA: partial opioid agonist,
prevents pleasurable effects, is a opiate analgesic
who: pregnant okay, must be in mild withdrawal to start
buprenorphine dosing ✔️Ans - must be in withdrawal to start
SL 8-32mg/d
which medications are in Suboxone ✔️Ans - buprenorphine and naloxone
buproprion; dosing ✔️Ans - for smoking cessation: begin 7-14d before stop
date; 150mg SR in am x6 days then increase to 150mg SR BID
tx for 7-9 weeks
chlordiazepoxide; MOA, what for, dosing ✔️Ans - MOA: enhances GABA
for acute alcohol withdrawal
50-100mg injectable every 2hrs
clonidine; MOA ✔️Ans - alpha 2 receptors
clonidine for opiate withdrawal ✔️Ans - blocks autonomic symptoms;
palpitations, sweating
clonidine for etoh withdrawal ✔️Ans - decrease bp, decrease HR, tremors
disulfiram; MOA ✔️Ans - inhibits acetalhydine and leads to buildup of
acetaldehyde and causes immediate hangover effect after alcohol
consumption
disulfiram dosing ✔️Ans - 250-500mg/d
flumazenil; MOA, use, dosing, se ✔️Ans - MOA: blocks benzo receptors at
GABA
use: benzo antidote
dosing: 0.4mg-3mg
se: dizzy, sweating, seizures, death
