PEBC Practice Exam| 535 Questions|
With Complete Solutions
serum level target (mmol/L) for Lithium in Adults and Elderly
correct answer: 1-1.2, 0.5-0.8
Which 2 parameters should be monitored at least Q6months for
patients taking Lithium? correct answer: thyroid, renal
which drug used for bipolar requires the patient to have a stable
salt and caffeine intake? correct answer: lithium
carbamazepine effect on CYP enzymes (induce/inhibit) correct
answer: induce
psychosis due to _________ dementia is worsened by use of
antipsychotics correct answer: Lewy body
which acetycholinesterase inhibitor showed slight benefit for
Lewy body dementia and Parkinson's diease dementia? correct
answer: rivastigmine
SSRI's can cause (hyper/hypo)natremia correct answer: hypo
____________ sensitivity is seen with Lewy body dementia,
characterized by rigidity, autonomic dysregulation, and
cognitive deterioration correct answer: antipsychotic
symptoms of major depressive episode must last for at least
__________ (length of time) correct answer: 2 weeks
,depressed mood for most of the day, for most days, for at least 2
years with at least 2 other symptoms = what kind of psychiatric
disorder? correct answer: persistent depressive disorder
(dysthymia)
based on the best available evidence, which 2 antidepressants
have the best efficacy and safety profile? correct answer:
escitalopram, sertraline
according to CANMAT guidelines, trazodone is considered
_________ line therapy for depression correct answer: second
3 common contraindications to bupropion are: correct answer:
seizures, anorexia, head trauma
compared to SSRI's, bupropion and mirtazapine has fewer
_____ and ____ side effects correct answer: sexual, GI
at dose of __________, venlafaxine also inhibits norepinephrine
reuptake correct answer: >150 mg
high doses of which class of antidepressants can cause
hypertension? correct answer: SNRI
phenelzine and tranylcypromine are classified as what class of
drug? correct answer: irreversible MAOI inhibitor
moclobemide is classified as what class of drug? correct answer:
reversible MAOI inhibitor
,switching from irreversible MAOI inhibitors to another agent
requires a washout period of _______ (lenght of time) correct
answer: 2 weeks
switching from reversible MAOI inhibiotrs to another agent
requires a washout period of ______ (length of time) correct
answer: 5 days
T/F: electroconvulsive therapy is 80-90% effective for
depression correct answer: T
which 2 SSRI's are preferred for breastfeeding? correct answer:
paroxetine, sertraline
which prokinetic agent has lower incidence of EPS correct
answer: domperidone
zinc gluconate is used for correct answer: anorexia nervosa
which antidepressant has the most evidence for bulimia nervosa
correct answer: fluoxetine
the diagnosis of insomnia = sleep disturbance for at least ____
nights per week for at least ____months correct answer: 3,3
which BZD must be taken at least 1 hour before bed for
hypnosis due to slow absorption correct answer: oxazepam
preferred hypnotic in pregnancy correct answer: zopiclone
, besides CBT, what are 2 first line options for OCD correct
answer: SSRI,SNRI
definition of schizophrenia = illness for ___ months and
psychotic symptoms for ____ months correct answer: 6,1
which 2 antipsychotics should be titrated rapidly to target dose
correct answer: ziprasidone, quetiapine XR
T/F: risk of relapse over 5 years after first episode psychosis is
70-90% correct answer: T
long acting injectables are (more/less/equal) effective than oral
antipsychotics correct answer: equal
when discontinuing antipsychotics, decrease dose by _____% or
less over _________ weeks correct answer: 20, 2-4
compared to the general population, schizophrenics have ____%
shorter life expectancy correct answer: 20
smoking induces metabolism of which 2 antipsychotics correct
answer: clozapine, olanzapine
muscle rigidity, fever, autonomic disturbance, labile BP,
fluctuating LOC, increased CK and WBC = ______ correct
answer: neuroleptic malignant syndrome
which 2 antipsychotics need to be taken with food correct
answer: lurasidone, ziprasidone
With Complete Solutions
serum level target (mmol/L) for Lithium in Adults and Elderly
correct answer: 1-1.2, 0.5-0.8
Which 2 parameters should be monitored at least Q6months for
patients taking Lithium? correct answer: thyroid, renal
which drug used for bipolar requires the patient to have a stable
salt and caffeine intake? correct answer: lithium
carbamazepine effect on CYP enzymes (induce/inhibit) correct
answer: induce
psychosis due to _________ dementia is worsened by use of
antipsychotics correct answer: Lewy body
which acetycholinesterase inhibitor showed slight benefit for
Lewy body dementia and Parkinson's diease dementia? correct
answer: rivastigmine
SSRI's can cause (hyper/hypo)natremia correct answer: hypo
____________ sensitivity is seen with Lewy body dementia,
characterized by rigidity, autonomic dysregulation, and
cognitive deterioration correct answer: antipsychotic
symptoms of major depressive episode must last for at least
__________ (length of time) correct answer: 2 weeks
,depressed mood for most of the day, for most days, for at least 2
years with at least 2 other symptoms = what kind of psychiatric
disorder? correct answer: persistent depressive disorder
(dysthymia)
based on the best available evidence, which 2 antidepressants
have the best efficacy and safety profile? correct answer:
escitalopram, sertraline
according to CANMAT guidelines, trazodone is considered
_________ line therapy for depression correct answer: second
3 common contraindications to bupropion are: correct answer:
seizures, anorexia, head trauma
compared to SSRI's, bupropion and mirtazapine has fewer
_____ and ____ side effects correct answer: sexual, GI
at dose of __________, venlafaxine also inhibits norepinephrine
reuptake correct answer: >150 mg
high doses of which class of antidepressants can cause
hypertension? correct answer: SNRI
phenelzine and tranylcypromine are classified as what class of
drug? correct answer: irreversible MAOI inhibitor
moclobemide is classified as what class of drug? correct answer:
reversible MAOI inhibitor
,switching from irreversible MAOI inhibitors to another agent
requires a washout period of _______ (lenght of time) correct
answer: 2 weeks
switching from reversible MAOI inhibiotrs to another agent
requires a washout period of ______ (length of time) correct
answer: 5 days
T/F: electroconvulsive therapy is 80-90% effective for
depression correct answer: T
which 2 SSRI's are preferred for breastfeeding? correct answer:
paroxetine, sertraline
which prokinetic agent has lower incidence of EPS correct
answer: domperidone
zinc gluconate is used for correct answer: anorexia nervosa
which antidepressant has the most evidence for bulimia nervosa
correct answer: fluoxetine
the diagnosis of insomnia = sleep disturbance for at least ____
nights per week for at least ____months correct answer: 3,3
which BZD must be taken at least 1 hour before bed for
hypnosis due to slow absorption correct answer: oxazepam
preferred hypnotic in pregnancy correct answer: zopiclone
, besides CBT, what are 2 first line options for OCD correct
answer: SSRI,SNRI
definition of schizophrenia = illness for ___ months and
psychotic symptoms for ____ months correct answer: 6,1
which 2 antipsychotics should be titrated rapidly to target dose
correct answer: ziprasidone, quetiapine XR
T/F: risk of relapse over 5 years after first episode psychosis is
70-90% correct answer: T
long acting injectables are (more/less/equal) effective than oral
antipsychotics correct answer: equal
when discontinuing antipsychotics, decrease dose by _____% or
less over _________ weeks correct answer: 20, 2-4
compared to the general population, schizophrenics have ____%
shorter life expectancy correct answer: 20
smoking induces metabolism of which 2 antipsychotics correct
answer: clozapine, olanzapine
muscle rigidity, fever, autonomic disturbance, labile BP,
fluctuating LOC, increased CK and WBC = ______ correct
answer: neuroleptic malignant syndrome
which 2 antipsychotics need to be taken with food correct
answer: lurasidone, ziprasidone
