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Lecture notes of 44 pages for the course BIOL 1210 at KPU (.)












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December 9, 2021
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2021/2022
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Campbell Biology
Second Canadian Edition




Chapter 15
The Chromosomal Basis of
Inheritance




Copyright © 2018 Pearson Canada Inc. 15 - 1

,Key Concepts (2 of 2)
• Alterations of chromosome number or structure cause
some genetic disorders

,Concept 15.4: Alterations of Chromosome Number or
Structure Cause Some Genetic Disorders
• Large-scale chromosomal alterations often lead to
spontaneous abortions (miscarriages) or cause a variety of
developmental disorders
• Plants tolerate such genetic changes better than animals
do

, Concept 17.5: Mutations of One or a Few Nucleotides
Can Affect Protein Structure and Function
• Mutations are changes in the genetic material of a cell or
virus
• If a mutation has an adverse effect on the phenotype of the
organism, the condition is referred to as a genetic disorder,
or hereditary disease
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