ONS Exam with all Correct & 100% Verified Answers |
Latest Update |Guaranteed to Pass
Cure ✔Correct Answer-Prolonged absence of disease
Control ✔Correct Answer-No further growth in the tumor
Palliation ✔Correct Answer-Comfort, pain control
Neoadjuvant ✔Correct Answer-Tx given as first step to shrink a tumor before the main tx,
usually surgery is given. Examples of neoadjuvant include chemo, radiation, and hormone
therapy.
Adjuvant therapy ✔Correct Answer-Is additional cancer tx. Given after primary tx to lower the
risk that cancer will come back. Adjuvant therapy may include chemo, radiation, hormone
therapy, targeted therapy, or biologic therapy.
Myeloablation. ✔Correct Answer-Obliteration of bone marrow with chemotherapeutic agents
administered in high doses of chemo in prep for a peripheral blood stem cell or bone marrow
transplant. Essentially the tx destroys blood forming cells in the bone marrow and reduces
tumor burden to make room for the new cells and destroys the patients immune system so it
cannot attach the donated cells after the transplant. I'm
Nonmyeloablative conditioning. ✔Correct Answer-Not as intense and uses doses of
chemotherapy that are not lethal to bone marrow. Use of nonmyeloblative regimens has
expanded the number of patients eligible for transplantation.
Immunosuppressive ✔Correct Answer-Suppression of the body's immune system and its
ability to fight infections and other diseases.
Single agent therapy ✔Correct Answer-Single agent is used to treat the cancer. Most single
agents are not able to "cure" cancer
Combination therapy ✔Correct Answer-More than one agent is used to create more exposure
of the cancer cells in the cell cycle, resulting in a higher tumor cell kill. Combination chemo uses
the principle of drug synergy to maximize the effects of another drug.
Dose density ✔Correct Answer-The drug dose per unit of time. This is when the chemo is
delivered over a shortened period of time. Reducing the amt of time between tx. May diminish
the growth of the tumor. It may be necessary to administer growth factors to patients to
prevent neutropenia.
, Dose intensity ✔Correct Answer-The ant of drug delivered over time. This equates to smaller
doses given more frequently. It is important to note that dose reductions or delays resulting
from chemotherapy side effects will reduce dose intensity And may have a negative impact on
the patients survival.
Relative dose intensity ✔Correct Answer-Is calculated by comparing the dose that the patient
received to the planned dose of the standard regimen. It is necessary to be proactive in
providing symptom management and educating patients on the importance of keeping to their
tx. Schedule.
Alkylating. Agents ✔Correct Answer-Nitrogen mustards include cytoxan, flex, treanda
Platinum based agents ✔Correct Answer-Consolation, carboplatin.
What is the usual recommendation regarding tx of patients receiving cyclophosphamide who
have the side effect of protracted severe hemorrhagic cystitis? ✔Correct Answer-Discontinue
treatment
Does cyclophosphamide have a boxed warning? ✔Correct Answer-No
Refer to package insert on previous page for cytoxan. What is the initial dose for patients
receiving oral cyclophosphamide? ✔Correct Answer-1 - 5 mg/kg/day
Does alkalating interfere with DNA replication? ✔Correct Answer-Yes
Does hypersensitivity interfere with late doses of carboplatin? ✔Correct Answer-Yes
Is tumor lysis syndrome possible in patients receiving alkalating. Agents when there is a vilify
tumor burden? ✔Correct Answer-Yes
What ore admission tests should be included for alkalating agents? ✔Correct Answer-Bun,
creatinine, and CNBC with differential.
When giving cytoxan and ifex, is means. usually given as a bladder protectant. ✔Correct
Answer-Yes
What are side effects of alkalating agents? ✔Correct Answer-Myelosuppression,
hypersensitivity reaction, renal impairment, go toxicities such as nausea and vomiting,
cutaneous reactions, neurotoxicities, secondary malignancies, alopecia.
Peripheral neuropathy. ✔Correct Answer-Platinum based chemotherapy
Cardiomyopathy ✔Correct Answer-Anthracyclines
Latest Update |Guaranteed to Pass
Cure ✔Correct Answer-Prolonged absence of disease
Control ✔Correct Answer-No further growth in the tumor
Palliation ✔Correct Answer-Comfort, pain control
Neoadjuvant ✔Correct Answer-Tx given as first step to shrink a tumor before the main tx,
usually surgery is given. Examples of neoadjuvant include chemo, radiation, and hormone
therapy.
Adjuvant therapy ✔Correct Answer-Is additional cancer tx. Given after primary tx to lower the
risk that cancer will come back. Adjuvant therapy may include chemo, radiation, hormone
therapy, targeted therapy, or biologic therapy.
Myeloablation. ✔Correct Answer-Obliteration of bone marrow with chemotherapeutic agents
administered in high doses of chemo in prep for a peripheral blood stem cell or bone marrow
transplant. Essentially the tx destroys blood forming cells in the bone marrow and reduces
tumor burden to make room for the new cells and destroys the patients immune system so it
cannot attach the donated cells after the transplant. I'm
Nonmyeloablative conditioning. ✔Correct Answer-Not as intense and uses doses of
chemotherapy that are not lethal to bone marrow. Use of nonmyeloblative regimens has
expanded the number of patients eligible for transplantation.
Immunosuppressive ✔Correct Answer-Suppression of the body's immune system and its
ability to fight infections and other diseases.
Single agent therapy ✔Correct Answer-Single agent is used to treat the cancer. Most single
agents are not able to "cure" cancer
Combination therapy ✔Correct Answer-More than one agent is used to create more exposure
of the cancer cells in the cell cycle, resulting in a higher tumor cell kill. Combination chemo uses
the principle of drug synergy to maximize the effects of another drug.
Dose density ✔Correct Answer-The drug dose per unit of time. This is when the chemo is
delivered over a shortened period of time. Reducing the amt of time between tx. May diminish
the growth of the tumor. It may be necessary to administer growth factors to patients to
prevent neutropenia.
, Dose intensity ✔Correct Answer-The ant of drug delivered over time. This equates to smaller
doses given more frequently. It is important to note that dose reductions or delays resulting
from chemotherapy side effects will reduce dose intensity And may have a negative impact on
the patients survival.
Relative dose intensity ✔Correct Answer-Is calculated by comparing the dose that the patient
received to the planned dose of the standard regimen. It is necessary to be proactive in
providing symptom management and educating patients on the importance of keeping to their
tx. Schedule.
Alkylating. Agents ✔Correct Answer-Nitrogen mustards include cytoxan, flex, treanda
Platinum based agents ✔Correct Answer-Consolation, carboplatin.
What is the usual recommendation regarding tx of patients receiving cyclophosphamide who
have the side effect of protracted severe hemorrhagic cystitis? ✔Correct Answer-Discontinue
treatment
Does cyclophosphamide have a boxed warning? ✔Correct Answer-No
Refer to package insert on previous page for cytoxan. What is the initial dose for patients
receiving oral cyclophosphamide? ✔Correct Answer-1 - 5 mg/kg/day
Does alkalating interfere with DNA replication? ✔Correct Answer-Yes
Does hypersensitivity interfere with late doses of carboplatin? ✔Correct Answer-Yes
Is tumor lysis syndrome possible in patients receiving alkalating. Agents when there is a vilify
tumor burden? ✔Correct Answer-Yes
What ore admission tests should be included for alkalating agents? ✔Correct Answer-Bun,
creatinine, and CNBC with differential.
When giving cytoxan and ifex, is means. usually given as a bladder protectant. ✔Correct
Answer-Yes
What are side effects of alkalating agents? ✔Correct Answer-Myelosuppression,
hypersensitivity reaction, renal impairment, go toxicities such as nausea and vomiting,
cutaneous reactions, neurotoxicities, secondary malignancies, alopecia.
Peripheral neuropathy. ✔Correct Answer-Platinum based chemotherapy
Cardiomyopathy ✔Correct Answer-Anthracyclines
