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NU260 Med-Surg II HESI Study Guide (Second Semester RN) Spring 2026

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Unit 1: Acute Neurological Disorders 1. Ischemic Stroke What it is: Blocked blood flow to brain tissue causing ischemia/infarction. Causes: Thrombotic, embolic, atrial fibrillation, carotid stenosis, HTN, diabetes, smoking, hyperlipidemia. Key Signs: Sudden unilateral weakness, facial droop, slurred speech, aphasia, confusion, vision changes, dysphagia, one-sided neglect. HESI Priorities: Last known well time, noncontrast CT first, NIH Stroke Scale, glucose first, swallow screen before PO. Treatment: tPA if eligible, mechanical thrombectomy, aspirin, later anticoagulants if embolic. Nursing: ABCs, neuro checks, aspiration precautions, fall precautions, HOB 30°, oxygenation, BP management, NPO until swallow cleared. HESI Traps: No PO before swallow eval, do not lower BP aggressively, CT before thrombolytics, hypoglycemia mimics stroke. 2. Hemorrhagic Stroke What it is: Bleeding into brain tissue or subarachnoid space. Causes: HTN, aneurysm rupture, AV malformation, trauma, anticoagulants

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NU260
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NU260

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Med-Surg II HESI Study Guide (Second Semester RN)


Unit 1: Acute Neurological Disorders



1. Ischemic Stroke

What it is: Blocked blood flow to brain tissue causing ischemia/infarction.

Causes: Thrombotic, embolic, atrial fibrillation, carotid stenosis, HTN, diabetes, smoking,
hyperlipidemia.

Key Signs: Sudden unilateral weakness, facial droop, slurred speech, aphasia, confusion, vision
changes, dysphagia, one-sided neglect.

HESI Priorities: Last known well time, noncontrast CT first, NIH Stroke Scale, glucose first,
swallow screen before PO.

Treatment: tPA if eligible, mechanical thrombectomy, aspirin, later anticoagulants if embolic.

Nursing: ABCs, neuro checks, aspiration precautions, fall precautions, HOB 30°, oxygenation, BP
management, NPO until swallow cleared.

HESI Traps: No PO before swallow eval, do not lower BP aggressively, CT before thrombolytics,
hypoglycemia mimics stroke.



2. Hemorrhagic Stroke

What it is: Bleeding into brain tissue or subarachnoid space.

Causes: HTN, aneurysm rupture, AV malformation, trauma, anticoagulants.

Key Signs: Sudden severe headache, N/V, decreased LOC, seizures, neuro deficits, nuchal
rigidity.

HESI Priorities: CT confirms bleed, no tPA, control BP, prevent rebleeding, watch ICP.

Treatment: BP control, surgery, seizure precautions, ICP management.

Nursing: Neuro checks, monitor increased ICP, seizure precautions, avoid straining, HOB 30°.

HESI Traps: No anticoagulants, no thrombolytics, sudden headache = hemorrhage until proven
otherwise.



Unit 2: GI Disorders Part 1

, 3. Hepatitis

Types: A/E fecal-oral, B/C blood/body fluids, D needs Hep B.

Signs: Fatigue, N/V, RUQ pain, jaundice, dark urine, clay stools, elevated AST/ALT.

HESI Priorities: Monitor liver function, avoid alcohol, avoid acetaminophen, rest, nutrition.

Nursing: Standard precautions, watch bleeding, monitor ammonia/LOC, teach transmission
prevention.

HESI Traps: Hep A/E fecal-oral, Hep B/C blood, dark urine + clay stool = obstructed bile flow.



4. Acute Pancreatitis

What it is: Acute pancreatic inflammation; pancreas digests itself.

Causes: Gallstones, alcohol, high triglycerides.

Signs: Severe LUQ/epigastric pain radiating to back, N/V, fever, tachycardia, distention,
decreased bowel sounds.

Labs: Elevated amylase, elevated lipase (most specific), low calcium, high glucose.

HESI Priorities: NPO, IV fluids, pain control, NG if severe, watch for shock.

Nursing: Assess Cullen’s sign, Grey Turner’s sign, strict I&O, monitor calcium, respiratory status.

HESI Traps: Lipase most specific, NPO priority, pain better leaning forward.



5. Chronic Pancreatitis

What it is: Long-term pancreatic damage.

Signs: Chronic pain, steatorrhea, weight loss, malabsorption, diabetes.

Nursing: Pancreatic enzymes, low-fat diet, no alcohol, pain control, monitor glucose.

HESI Trap: Chronic = malabsorption + diabetes.



6. Cirrhosis

What it is: Chronic liver scarring leading to liver failure.

Causes: Alcohol, hepatitis, fatty liver disease.

Signs: Jaundice, ascites, edema, varices, bruising, confusion, asterixis.

Labs: Elevated bilirubin, elevated PT/INR, low albumin, elevated ammonia.

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