CHAMBERLAIN
UNIVERSITY
Comprehensive Clinical
Evaluation Assessment
(CEA) | 2 VERSIONS
Practice Questions with
Verified Answers &
Rationales Latest
2026/2027 Update
INTRODUCTION
,This comprehensive practice exam is designed for students preparing for the NR
511 Comprehensive Clinical Evaluation Assessment (CEA) at Chamberlain
University. The NR 511 CEA exam tests mastery of:
Differential Diagnosis – Clinical reasoning, diagnostic frameworks, and
condition recognition
Primary Care Practicum – Management of acute and chronic conditions
across the lifespan
Advanced Health Assessment – System-based examination techniques and
findings
Evidence-Based Practice – Clinical guidelines, screening recommendations,
and treatment protocols
The following questions cover high-yield topics commonly tested on the CEA
exam .
SECTION 1: CLINICAL REASONING & DIFFERENTIAL DIAGNOSIS (Questions 1-20)
1. A 48-year-old man presents with intermittent epigastric pain for 3 months.
You begin the visit by asking when the pain started, where he feels it, how long
each episode lasts, and what makes it better or worse using OLDCARTS. Which
part of the diagnostic reasoning process are you performing?
A. Review of systems
B. History of present illness
C. Functional health patterns
D. Problem list formulation
Rationale: The History of Present Illness (HPI) is a focused, detailed
breakdown of the chief complaint using OLDCARTS (Onset, Location, Duration,
Characteristics, Aggravating factors, Relieving factors, Treatments, Severity),
which is exactly what is being gathered in this scenario .
,2. A 67-year-old woman tells you she has had "aching all over" for weeks and
feels "exhausted." You note her blood pressure, heart rate, and gait. You also
observe she appears fatigued. Which type of data is the patient's statement
about feeling exhausted?
A. Subjective
B. Objective
C. Assessment
D. Plan
Rationale: Subjective data includes information provided by the patient,
including symptoms, feelings, perceptions, and health history. The patient's
statement about feeling exhausted is subjective because it reflects their personal
experience and cannot be independently measured by the clinician .
3. After gathering data from a patient with chest pain, the NP documents the
diagnosis and differentials. In which section of the SOAP note should the
diagnosis be documented?
A. Subjective
B. Objective
C. Assessment
D. Plan
Rationale: The diagnosis and differentials belong in the Assessment section,
which contains the clinician's synthesis and interpretation of subjective and
objective findings .
4. A 50-year-old man with chest pain undergoes a highly sensitive troponin test
that returns negative. How is this result best interpreted?
A. The disease is ruled in
B. The disease is likely ruled out
C. The disease prevalence is high
D. The test is unreliable
, Rationale: A highly sensitive test has few false negatives; therefore, a
negative result makes the presence of disease unlikely. This follows the SNOUT
principle: a Sensitive test, when Negative, rules OUT disease .
5. A 42-year-old woman is being tested for a rare autoimmune condition with
very low prevalence. Even with a good test, what impact does the low
prevalence have on the test's positive predictive value (PPV)?
A. PPV increases
B. PPV decreases
C. PPV is unchanged
D. PPV equals test sensitivity
Rationale: Positive predictive value depends on disease prevalence; low
prevalence yields a low PPV and higher likelihood that positive results are false
positives .
6. In reviewing evidence for a new IBS treatment, you find a meta-analysis of
several randomized controlled trials (RCTs). According to evidence-based
practice, what level of evidence is this?
A. Level III
B. Level V
C. Level I
D. Level VII
Rationale: Systematic reviews and meta-analyses of randomized controlled
trials are categorized as Level I evidence, representing the highest level for guiding
practice changes .
7. You are looking for a single, well-designed randomized controlled trial
examining proton pump inhibitors in GERD. Which level of evidence does this
represent?