,1. Cellular Biology
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2. Altered Cellular and Tissue Biology
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3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases
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4. Genes and Genetic Diseases
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5. Epigenetics and Disease
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6. Genes, Environment–Lifestyle, and Common Diseases
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7. Innate Immunity: Inflammation and Wound Healing
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8. Adaptive Immunity
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9. Alterations in Immunity and Inflammation
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10. Infection
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11. Stress and Disease
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12. Biology, Clinical Manifestations, and Treatment of Cancer
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13. Alterations in Oxygen Transport
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14. Alterations in Hemostasis and Coagulation
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15. Alterations in White Blood Cell Function
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16. Alterations in Cardiovascular Function
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17. Shock, Sepsis, and Multiple Organ Dysfunction Syndrome
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18. Alterations of Pulmonary Function
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19. Alterations of Hormonal Regulation
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20. Alterations of Hematologic Function in Children
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21. Alterations of Cardiovascular Function in Children
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22. Alterations of Pulmonary Function in Children
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23. Structure and Function of the Neurologic System
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24. Pain, Temperature, Sleep, and Sensory Function
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25. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
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26. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
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27. Alterations of Neurologic Function in Children
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28. Structure and Function of the Endocrine System
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29. Mechanisms of Hormonal Regulation
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30. Alterations of Endocrine Function
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31. Alterations of Renal and Urinary Tract Function
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32. Alterations of Digestive Function
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33. Alterations of Liver and Biliary Function
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34. Alterations of Musculoskeletal Function
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35. Alterations of Reproductive Function
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y1
,Chapter 1. Cellular Biology y1 y1 y1
MULTIPLE CHOICE y1
1. A student is observing a cell under the microscope. It is observed to have supercoil
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ed DNA with histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
y1 y1 y1
b. A nucleus y1
c. Free-floating nuclear material y1 y1
d. No organelles y1
ANS: B y1
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its n
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ucleus; thus, the nucleus should be observed. A single circular chromosome is characteristic of
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y
1prokaryotic cells, which do not have histones. Free-
y1 y1 y1 y1 y1 y1 y1
floating nuclear material describes a prokaryotic cell, which would not have a distinct nucleu
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
s. Eukaryotic cells have membrane-
y1 y1 y1 y1
bound cellular components called organelles. No organelles describe a prokaryotic cell.
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
2. A nurse is instructing the staff about cellular functions. Which cellular function
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
is the nurse describing when an isolated cell absorbs oxygen and uses it to transform
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
nutrients to energy? y1 y1
a. Metabolic absorption y1
b. Communication
c. Secretion
d. Respiration
ANS: D y1
The ability of the cell to absorb oxygen refers to the cells function of respiration. The ability
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
of the cell to function within a society of cells refers to its function of communication. The
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ability of the cell to take in nutrients refers to the cells function of metabolic absorption.The
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ability of the cell to synthesize new substances and secrete these elsewhere refers to the cel
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ls function of secretion.
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y1
, 3. A eukaryotic cell is undergoing DNA replication. In which region of the cell wou
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ld most of the genetic information be contained?
y1 y1 y1 y1 y1 y1 y1
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS: C y1
The region of the cell that contains genetic material, including a large amount of ribonucleic
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
acid, most of the DNA, and DNA-
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binding proteins, is the nucleolus. The mitochondria is the site of cellular respiration. The ribo
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
somes are involved in the manufacturing of proteins within the cell. The nucleus contains the
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y
nucleolus, and it is the nucleolus that contains genetic material.
1 y1 y1 y1 y1 y1 y1 y1 y1 y1
4. The fluid- y1
mosaic model for biologic membranes describes membrane behavior. According to t
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
his model, which of the following float singly or as aggregates in the fluid lipid bilaye
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
r?
a. Peripheral membrane proteins y1 y1
b. Integral membrane proteins y1 y1
c. Glycoproteins
d. Cell adhesion molecules
y1 y1
ANS: B y1
Integral membrane proteins float freely in the fluid lipid bilayer. Peripheral membrane proteins
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
are not embedded in the layer, but reside at the surface. Glycoproteins act as cell surface ma
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
rkers. Cell adhesion molecules are on the outside of the membrane and allow cells to hook to
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
gether.
y1
y1 y1
2. Altered Cellular and Tissue Biology
y1 y1 y1 y1 y1
3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases
y1 y1 y1 y1 y1 y1 y1 y1 y1
4. Genes and Genetic Diseases
y1 y1 y1 y1
5. Epigenetics and Disease
y1 y1 y1
6. Genes, Environment–Lifestyle, and Common Diseases
y1 y1 y1 y1 y1
7. Innate Immunity: Inflammation and Wound Healing
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8. Adaptive Immunity
y1 y1
9. Alterations in Immunity and Inflammation
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10. Infection
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11. Stress and Disease
y1 y1 y1
12. Biology, Clinical Manifestations, and Treatment of Cancer
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13. Alterations in Oxygen Transport
y1 y1 y1 y1
14. Alterations in Hemostasis and Coagulation
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15. Alterations in White Blood Cell Function
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16. Alterations in Cardiovascular Function
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17. Shock, Sepsis, and Multiple Organ Dysfunction Syndrome
y1 y1 y1 y1 y1 y1 y1
18. Alterations of Pulmonary Function
y1 y1 y1 y1
19. Alterations of Hormonal Regulation
y1 y1 y1 y1
20. Alterations of Hematologic Function in Children
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21. Alterations of Cardiovascular Function in Children
y1 y1 y1 y1 y1 y1
22. Alterations of Pulmonary Function in Children
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23. Structure and Function of the Neurologic System
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24. Pain, Temperature, Sleep, and Sensory Function
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25. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
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26. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
27. Alterations of Neurologic Function in Children
y1 y1 y1 y1 y1 y1
28. Structure and Function of the Endocrine System
y1 y1 y1 y1 y1 y1 y1
29. Mechanisms of Hormonal Regulation
y1 y1 y1 y1
30. Alterations of Endocrine Function
y1 y1 y1 y1
31. Alterations of Renal and Urinary Tract Function
y1 y1 y1 y1 y1 y1 y1
32. Alterations of Digestive Function
y1 y1 y1 y1
33. Alterations of Liver and Biliary Function
y1 y1 y1 y1 y1 y1
34. Alterations of Musculoskeletal Function
y1 y1 y1 y1
35. Alterations of Reproductive Function
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y1
,Chapter 1. Cellular Biology y1 y1 y1
MULTIPLE CHOICE y1
1. A student is observing a cell under the microscope. It is observed to have supercoil
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ed DNA with histones. Which of the following would also be observed by the student?
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
a. A single circular chromosome
y1 y1 y1
b. A nucleus y1
c. Free-floating nuclear material y1 y1
d. No organelles y1
ANS: B y1
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its n
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ucleus; thus, the nucleus should be observed. A single circular chromosome is characteristic of
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y
1prokaryotic cells, which do not have histones. Free-
y1 y1 y1 y1 y1 y1 y1
floating nuclear material describes a prokaryotic cell, which would not have a distinct nucleu
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
s. Eukaryotic cells have membrane-
y1 y1 y1 y1
bound cellular components called organelles. No organelles describe a prokaryotic cell.
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
2. A nurse is instructing the staff about cellular functions. Which cellular function
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
is the nurse describing when an isolated cell absorbs oxygen and uses it to transform
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
nutrients to energy? y1 y1
a. Metabolic absorption y1
b. Communication
c. Secretion
d. Respiration
ANS: D y1
The ability of the cell to absorb oxygen refers to the cells function of respiration. The ability
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
of the cell to function within a society of cells refers to its function of communication. The
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ability of the cell to take in nutrients refers to the cells function of metabolic absorption.The
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ability of the cell to synthesize new substances and secrete these elsewhere refers to the cel
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ls function of secretion.
y1 y1 y1
y1
, 3. A eukaryotic cell is undergoing DNA replication. In which region of the cell wou
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
ld most of the genetic information be contained?
y1 y1 y1 y1 y1 y1 y1
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS: C y1
The region of the cell that contains genetic material, including a large amount of ribonucleic
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
acid, most of the DNA, and DNA-
y1 y1 y1 y1 y1 y1
binding proteins, is the nucleolus. The mitochondria is the site of cellular respiration. The ribo
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
somes are involved in the manufacturing of proteins within the cell. The nucleus contains the
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y
nucleolus, and it is the nucleolus that contains genetic material.
1 y1 y1 y1 y1 y1 y1 y1 y1 y1
4. The fluid- y1
mosaic model for biologic membranes describes membrane behavior. According to t
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
his model, which of the following float singly or as aggregates in the fluid lipid bilaye
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
r?
a. Peripheral membrane proteins y1 y1
b. Integral membrane proteins y1 y1
c. Glycoproteins
d. Cell adhesion molecules
y1 y1
ANS: B y1
Integral membrane proteins float freely in the fluid lipid bilayer. Peripheral membrane proteins
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
are not embedded in the layer, but reside at the surface. Glycoproteins act as cell surface ma
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
rkers. Cell adhesion molecules are on the outside of the membrane and allow cells to hook to
y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1 y1
gether.
y1