PCCN Review Questions and answers

PCCN Review Questions and answers Thrombocytopenia - Normal range 150,00-350,000, causes are heparin induced, DIC, Anti-platelet drugs DIC: Disseminated Intravascular Coagulopathy - Syndrome characterized by thrombus formation and hemorrhage. Forms clots in small blood vessels in the body. Secondary to stimulation of normal coagulation process, with resultant decrease in clotting factors and platelets-platelet dysfunction. Factors triggering DIC - Tissue factors: Tissue breakdown, Platelet aggregation: Sepsis, Injury to vascular endothelium and exposure to collagen... Etiology of DIC - Vascular disorders, Infection and Sepsis, Hematological and immune disorders, Anaphylaxis- histamine release with fluid movement causing edema and vasodilation, blood transfusion reaction, massive blood transfusion, prolonged cardiopulmonary bypass, sickle cell crisis, transplant reaction, trauma, burns, acute anoxia, crush and head injury, cancer, OB complications