NR 566 Midterm Study Guide | Complete Pharmacology Review | Antibiotics, Weight Loss, Antivirals

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NR 566 Midterm NR566 MIDTERM EXAM
REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE

Which non- o




amphetamines are FDA approved for weight loss that have lower abuse risk? ...
o o o o o o o o o o o o




.......ANSWER.......Phentermine and Diethylpropion o o




How does Phentermine and Diethylpropion promote weight loss? ..........ANS
o o o o o o o o




WER.......-Promote weight loss by decreasing appetite
o o o o o




-
They are central nervous system (CNS) stimulants that suppress appetite by in
o o o o o o o o o o o




creasing the availability of norepinephrine at receptors in the brain
o o o o o o o o o




What is the maximum recommended duration of use for non-
o o o o o o o o o




amphetamines? ..........ANSWER.......3 months or less
o o o o




What drug schedule are Phentermine and Diethylpropion under? ..........ANS
o o o o o o o o




WER.......Schedule IV o

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What labs should be monitored with Phentermine and Diethylpropion? What
o o o o o o o o o o




condition should we screen for? ..........ANSWER.......-
o o o o o




baseline CMP (watch electrolytes and creatinine)
o o o o o




-screen for depression o o




Phentermine adverse effects ..........ANSWER.......-increase HR and BP
o o o o o o




-dry mouth and constipation
o o o




What is role of topiramate in weight loss? ..........ANSWER.......Increases satiety
o o o o o o o o o




What are some Phentermine/topiramate contraindications for use? ..........AN
o o o o o o o




SWER.......not approved in children and contraindicated with severe hepatic i
o o o o o o o o o




mpairment



How should we educate patient to take Phentermine/topiramate to avoid inso
o o o o o o o o o o




mnia? ..........ANSWER.......given before 1600
o o o




What are some high-
o o o




risk patient conditions that we should use Phentermine/topiramate with cauti
o o o o o o o o o




on? ..........ANSWER.......hx drug abuse, glaucoma, pregnant, HTN, hyperthyroi
o o o o o o o




dism

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Phentermine/topiramate adverse effects ..........ANSWER.......insomnia, nervo o o o o




usness, anxiety, depression, blurred vision
o o o o




Which of the following would be a contraindication to prescribing phentermi
o o o o o o o o o o




ne/topiramate? Select all that apply. ..........ANSWER.......A) Glaucoma
o o o o o o




B) Hypothyroidism
o




C) Hypertension
o




D) Hyperthyroidism
o




E) Vitamin D Deficiency
o o o




F) A, B, E
o o o




ANSWER: A,C,D o




Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption
o o o o o o o o o o o o




o of fat by 30%. ..........ANSWER.......GI tract
o o o o o




Take multivitamin ___hours before/after to supplement fat-
o o o o o o




soluble vitamins that may not be absorbed well when taking Orlistat. ..........A
o o o o o o o o o o o




NSWER.......2

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Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. .......
o o o o o o o o o o o o o o




...ANSWER.......12



Orlistat results in the least amount of weight loss of all. How much? ..........ANS
o o o o o o o o o o o o o




WER.......2-3% body weight (7 lbs in year)
o o o o o o




Orlistat adverse effects ..........ANSWER.......Fecal incontinence, oily rectal leak
o o o o o o o




age, flatus, abdominal cramps. liver damage (light-
o o o o o o




colored stools, dark urine, fatigue, jaundice, anorexia)
o o o o o o




When is Orlistat contraindicated? ..........ANSWER.......In those with malabsor
o o o o o o o




ption syndrome or cholestasis
o o o




What vitamin deficiency are we concerned about when taking Orlistat...especi
o o o o o o o o o




ally if the patient is on coumadin? ..........ANSWER.......Monitor Coumadin as V
o o o o o o o o o o




itamin K deficiency may occur and intensify effect of Coumadin.
o o o o o o o o o




A patient with a BMI of 27 would be considered: ..........ANSWER.......overweig
o o o o o o o o o o




ht