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HESI A2 Anatomy & Physiology | 2026 Exam Q&A | 250+ Verified Questions | Hormones, Muscles, Bones, Brain, Organs

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This document offers a comprehensive set of 250+ verified, A+-graded multiple-choice and short-answer questions aligned with the 2026 HESI A2 Anatomy and Physiology exam. Covering 30 full pages of Q&A-based content, it is designed to maximize exam readiness for students entering nursing and allied health programs. The format replicates the HESI exam style and supports both deep concept mastery and quick-recall review. Key concepts include: Histology and four fundamental tissue types (epithelial, connective, muscle, nerve) Muscle structure and contraction mechanics (sarcomeres, myosin-actin interaction, calcium role, ATP, motor neurons) Skeletal system anatomy including axial and appendicular bones, vertebrae, and joints Nervous system and brain function (neuron structure, CNS/PNS, spinal reflexes, cerebrum, medulla) Hormonal systems (pituitary hormones, tropic hormones, steroid vs. nonsteroid, AMP as second messenger) Cardiovascular and blood system (heart chambers, valves, cardiac cycle, blood types, leukocytes, hemoglobin) Respiratory system (gas exchange, breathing control, role of diaphragm and alveoli) Digestive, urinary, and reproductive systems (chyme, bile, nephron, sperm development, ovulation, placenta function) Each section provides immediate feedback through clearly marked answers and detailed memory aids (e.g., mnemonics and diagrams) for better concept retention. Ideal for: HESI A2 test-takers preparing for 2026 Pre-nursing and allied health students LPN, ADN, BSN program candidates Foundational A&P learners needing structured reinforcement Keywords: HESI A2 2026, anatomy and physiology, hormones, tissue types, skeletal system, muscle contraction, sarcomere, myosin, brain function, neurons, endocrine glands, cardiac cycle, blood cells, alveoli, nephron, chyme, placenta, ovulation, reproductive system, verified Q&A, nursing entrance prep

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HESI A2 Anatomy and Physiology 2026
Exam Questions and Verified Answers |
Already Graded A+



What is histology? - 🧠ANSWER ✔✔The study of tissues


What is a tissue? - 🧠ANSWER ✔✔A group of cells that act together to

perform a specific function.


What are the fundamental tissues? - 🧠ANSWER ✔✔Epithelial


Connective

Muscle

Nerve

,(Elephants Can Make News)


What is the function of epithelial cells? - 🧠ANSWER ✔✔Cover, line, and

protect the body and the internal organs.


What is the function of connective tissue? - 🧠ANSWER ✔✔Framework of

the body. Provides support and structure to organs.


What is neuroglia? - 🧠ANSWER ✔✔The neurons and connective tissue

cells that compose nerve tissue.


What ability does muscle tissue have? - 🧠ANSWER ✔✔Ability to contract

and shorten.


What is muscle tissue classified as? - 🧠ANSWER ✔✔Voluntary(skeletal

muscles) and involuntary(smooth & cardiac)


What is meiosis? - 🧠ANSWER ✔✔The cell division that takes place in the

gonads, i.e. the ovaries and testes.


What two layers compose the skin? - 🧠ANSWER ✔✔Epidermis and dermis.


What is the epidermis? - 🧠ANSWER ✔✔The outermost protective layer of

dead keratinized epithelial cells.

, What is the dermis? - 🧠ANSWER ✔✔The underlying layer of connective

tissue with blood vessels, nerve endings, and the associated skin tissues.


What are the layers of the epidermis? - 🧠ANSWER ✔✔Corneum


Lucidum

Granulosum

Germivatum ( basale & spinosum)

Mnemonic: Candy Lions Growl Great.

What does the protein pigment melanin protect against? - 🧠ANSWER

✔✔Radiation from the Sun


What is the dermis composed of? - 🧠ANSWER ✔✔Fibrous connective

tissue with nerve endings, blood vessels, sensory nerve endings, hair

follicles, and glands.


What are the 2 types of sweat glands? - 🧠ANSWER ✔✔ecrine & apocrine


What do ecrine sweat glands produce? - 🧠ANSWER ✔✔Sweat. Regulate

body temperature.




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