NRNP 6675 FINAL EXAM WITH ALL ANSWERS.

NRNP 6675 FINAL EXAM WITH ALL ANSWERS
b b b b b b




1. The b1/2 blife bof blithium bis babout?
b b b b b b 24 bhours
b




2. Fluoxetine bis bthe bSSRI bwith bthe b
b b b b b b WD lowest bdue bto blong bhalf blife
b b b b b




brisk?
b




3. What bantipsychotics bare bgood bfor bpts
b b b b b

Antipsychotics bwith b




bwho bmiss bdoses bof btheir bmeds?
b b b b b b
blong bhalf-lives:
b b




1.Cariprazine(Vrylar):
b(2-4
b bdays-active b




bmetabolites bup bto b3
b b b b




bweeks)
b




2.Abilify b(3 bdays) b b




3.Brexipiprazole b(4 bdays) b b




4.Pimozide b(4-5 bdays) b b




5.Pimavanserin b(2 bdays, b b




bac- btive bmetabolites b8
4. Disulfiram's balcohol binteractions bpersist
b b b b




bdays)
b b b




bfor bup bto bhow blong bafter bthe bmedication
b




b b b b b b b b




bis bstopped?
b b

LONG bHalf blife--2-3 bdays
b b b




1 b/ b



b44
b

,persist bup bto b2 bweeks bfollow- bing bstopping
b b b b b b b




5. What bis bthe bonly bTCA bwith ba blong bhalf blife? Protriptyline b(Vivactil)
b b b b b b b b b b




6. Most bpsychotropics bhave ba bmedium
b b b b

24 bhours
b




brange b1/2 blife bof bapprox?
b b b b b




7. what bdoes b"steady bstate" bmean bin brelation steady bstate bmeans
b b b b b b

b b




bto b1/2 blife? bthat byou bare
b b b

b b b




beliminating bthe bdrug bat b b b b




bthe bsame boverall brate b b b b




bthat byou bare bingesting b b b b




bit b




8. Lithium breaches bits b'steady bstate' bwhen?
b b b b b 5 bhalf blives
b b




example:
Day b1: bStart bpt bon
b b b b




bLithium b600 bmg bdaily
b b b b




Day b2: b(24 bhours blater)
b b b b




bthe bamount bleft bin bhis
b b b b b




bbody bis b300 bmg b(day b2
b b b b b b




bmin) bbecause b24 bhours
b b b b




bhas bpassed--one
b b




2 b/b



b44
b

, 1/2 blife--therefore bthe bpt b b b




bhas bexcreted b1/2 bof bthe b b b b b




binitial bamount. b b




THEN bthe bpt btakes bhis b b b b




b2nd bdose bof b600 bmg bon b b b b b b




bDAY b2-re- bsulting bin ba b b b b b




bmax bdose bof b900 b(300 b b b b b




bmg bleft bin bbody b+ b600 b b b b b b




bmg bof b2nd bdose). b b b b




DAY b3: bstarts boff bwith b b b b




b450 bmg b(1/2 bof bthe b900 b b b b b b




bmg bin bpt's bsys- btem) b b b b b




band bafter btaking bthe b b b b




bday b3 b600 bmg bdose, b b b b b




9. Due bto bthe bsteady bstate bof bLithium, bwhen bthe bpt bnow bhas ba btotal
b b b b b b b b b b b b b




bdo bwe bdraw ba bblood blevel?
b b b b b bof b1050 bmg.
b b b b




5 bhalf blives
b b




if byou bcheck bany bearlier,
b b b b




bthe btrough blevel bwill
b b b b




bunderesti- bmate bthe
b b b




bactual blevel bthe bpt bis
b b b b b




bon bafter bachieving
b b b




bsteady bstate
b b




10. Fluoxetine bhas ba bhalf blife bof babout?
b b b b b b 2 bweeks b1/2 blife
b b b




take b2.5 bmonths bto
b b b




bachieve bsteady bstate
b b b




11. Most bpsychotropic bmedications boperate
b b b 12. induces bit's b




bin bthis bfashion:
b b b b bown bmetabolism, b




b bhastening bexcretion b




b band bshortening bit's b b




b bhalf blife b




3 b/ b



b44
b

,"when byou bdouble bthe bdose, bthe bserum b b b b b b




bdose bdoubles."
b b




*minus bthree bSRIs band bthree b b b b




banticonvulsants b(Flu- boxetine,
b b b




bfluvoxamine, bpaxil, bgabapentin, bvalproate
b b b b




band bcarbamazepine)
b b




A. bCarbamazepine b(Tegre- btol) b b b




*this beffect bbegins bto b"rev b b b b




4 b/b



b44
b