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VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 8th Edition
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, MULTIPLE CHOICE x*
1. Which of the following would be the most likely cause of a
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n iatrogenic disease?
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a. An inherited disorderx* x*
b. A combination of specific etiological factors
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c. An unwanted effect of a prescribed drug
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d. Prolonged exposure to toxic chemicals in the environment x* x* x* x* x* x* x*
ANS: C x*
2. The manifestations of a disease are best defined as the
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a. subjective feelings of discomfort during a chronic illness. x* x* x* x* x* x* x*
b. signs and symptoms of a disease.x* x* x* x* x*
c. factors that precipitate an acute episode of a chronic illness.
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d. early indicators of the prodromal stage of infection.
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ANS: B x*
3. The best definition of the term prognosis is the
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a. precipitating factors causing an acute episode. x* x* x* x* x*
b. number of remissions to be expected during the course of a chronic illness.
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c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronic illness. x* x* x* x*
ANS: C x*
4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee x* x* x*
b. Fever
c. Pain in the neck x* x* x*
d. Red rash on the face x* x* x* x*
ANS: B x*
5. Etiology is defined as the study of the
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a. causes of a disease. x* x* x*
b. course of a disease. x* x* x*
c. expected complications of a disease. x* x* x* x*
d. manifestations of a disease. x* x* x*
ANS: A x*
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as
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a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D x*
7. A change in a tissue marked by cells that vary in size and shape and show increased mito
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tic figures would be called
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, a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C x*
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called
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a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B x*
9. When a group of cells in the body dies, the change is called
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a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D x*
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle cell
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s undergoing
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a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A x*
11. The term cancer refers to
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. x*
ANS: D x*
12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells x* x* x* x* x* x*
b. Ischemic damage to cells x* x* x*
c. Liquefaction of necrotic tissue x* x* x*
d. Preprogrammed cell self-destruction x* x*
ANS: D x*
13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function. x* x* x* x* x* x* x*
b. Damaged cells may be able to repair themselves. x* x* x* x* x* x* x*
c. All types of cells die at the same rate.
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d. Mild ischemia causes immediate cell death.
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ANS: B x*
14. Caseation necrosis refers to an area wherex* x* x* x* x* x*
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, a. cell proteins have been denatured.
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