1: i
2.
3. c
4. M
5 most ___________ because they contain ___________, ___________ or both
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1. iron
2. milk products
3. calcium
4.magnesium containing laxatives
5. antacids; magnesium; aluminum
GI adverse effects of _____________ are N/V/D and ________ _____. take ______________ with meals
but in form that's unaffected by food!
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macrolides
epigastric pain
erythromycin
nephrotoxic drugs like aspirin, ______________________ _, vancomycin, ______ and cyclosporine
can increase risk for renal damage when given concurrently with ______________
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amphotericin B
NSAIDs
aminoglycosides
only use __________ when pt can't be treated with a more narrow spectrum abx
can only be given via __, not well absorbed in GI tract
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carbapenems
IV
can effectively penetrate gram negative cell envelope
ototoxcity happens when taking ______________ DT excessive ________ levels, impairing
hearing and balance
, 1st sign of ototoxicity is ________- __________ ____________, irreversible
1 st sign of imbalance is ___, lasts for 1-2 days then vertigo, dizziness
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aminoglycosides
trough
high-pitched ringing
HA
high dose of ____________ IV therapy can cause severe _______ damage
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tetracycline
liver
Does Vancomycin interact with PBPs? If it does, how does it work? if not, how does it
work?
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NO
it stops synthesis by binding to molecules that serve as precursors for cell
wall biosynthesis
____________ can also inhibit ________________- transmission leading to flaccid paralysis and
fatal __________________ depression