TRACE ELEMENTS QUESTIONS AND
CORRECT ANSWERS
traceA2elementsA2-A2Ans--
AnA2elementA2indispensableA2forA2lifeA2butA2requiredA2inA2extremelyA2minuteA2amounts.
LowA2bloodA2concentrationA2ofA2element
mg/dlA2(bodyA2fluids)A2orA2lessA2(partsA2perA2million)
ex)A2iron,A2cooper,A2zinc
ultratraceA2elementsA2-A2Ans--
elementsA2requiredA2byA2theA2bodyA2inA2veryA2minuteA2amounts
BloodA2levelsA2inA2rangesA2ofA2ug/dlA2orA2ug/kgA2(partA2perA2billion)
ex)A2selenium,A2chromium,A2andA2manganese
essentialA2traceA2elementsA2-A2Ans---
ConsideredA2essentialA2ifA2aA2deficientA2stateA2thatA2impairsA2functionA2isA2wellA2defined.
-DecreaseA2stateA2canA2beA2reversedA2byA2takingA2element.
-ThereA2mustA2beA2aA2biochemicalA2basisA2forA2theA2element.
-
AreA2oftenA2associatedA2withA2anA2enzymeA2(metalloenzyme)A2orA2anotherA2proteinA2(met
alloprotein)A2asA2aA2cofactor
-ExcessA2concentrationsA2associatedA2withA2someA2degreeA2ofA2toxicity
WhatA2isA2theA2clinicalA2significanceA2ofA2traceA2elementsA2-A2Ans--
ServesA2aA2biologicalA2roleA2inA2humansA2andA2animals
AssociatedA2w/
A2enzymeA2(metalloenzyme)A2orA2anotherA2proteinA2(metalloprotein)A2asA2cofactor
MaybeA2toxicA2atA2higherA2levels
WhyA2isA2measuringA2tranceA2elementsA2challengingA2-A2Ans--
•LaboratoryA2issuesA2withA2testingA2traceA2andA2ultatraceA2elements:
-
ComplexA2analyticalA2techniquesA2mustA2beA2maintainA2forA2sensitivity,A2precisionA2andA2
accuracy.
-ContaminationA2ofA2specimens
-InterpretationA2andA2analysisA2areA2timeA2sensitive
IdentifyA2methodsA2useA2forA2analysisA2ofA2traceA2metalsA2-A2Ans--
•AtomicA2EmissionA2SpectroscopyA2(AES)
CORRECT ANSWERS
traceA2elementsA2-A2Ans--
AnA2elementA2indispensableA2forA2lifeA2butA2requiredA2inA2extremelyA2minuteA2amounts.
LowA2bloodA2concentrationA2ofA2element
mg/dlA2(bodyA2fluids)A2orA2lessA2(partsA2perA2million)
ex)A2iron,A2cooper,A2zinc
ultratraceA2elementsA2-A2Ans--
elementsA2requiredA2byA2theA2bodyA2inA2veryA2minuteA2amounts
BloodA2levelsA2inA2rangesA2ofA2ug/dlA2orA2ug/kgA2(partA2perA2billion)
ex)A2selenium,A2chromium,A2andA2manganese
essentialA2traceA2elementsA2-A2Ans---
ConsideredA2essentialA2ifA2aA2deficientA2stateA2thatA2impairsA2functionA2isA2wellA2defined.
-DecreaseA2stateA2canA2beA2reversedA2byA2takingA2element.
-ThereA2mustA2beA2aA2biochemicalA2basisA2forA2theA2element.
-
AreA2oftenA2associatedA2withA2anA2enzymeA2(metalloenzyme)A2orA2anotherA2proteinA2(met
alloprotein)A2asA2aA2cofactor
-ExcessA2concentrationsA2associatedA2withA2someA2degreeA2ofA2toxicity
WhatA2isA2theA2clinicalA2significanceA2ofA2traceA2elementsA2-A2Ans--
ServesA2aA2biologicalA2roleA2inA2humansA2andA2animals
AssociatedA2w/
A2enzymeA2(metalloenzyme)A2orA2anotherA2proteinA2(metalloprotein)A2asA2cofactor
MaybeA2toxicA2atA2higherA2levels
WhyA2isA2measuringA2tranceA2elementsA2challengingA2-A2Ans--
•LaboratoryA2issuesA2withA2testingA2traceA2andA2ultatraceA2elements:
-
ComplexA2analyticalA2techniquesA2mustA2beA2maintainA2forA2sensitivity,A2precisionA2andA2
accuracy.
-ContaminationA2ofA2specimens
-InterpretationA2andA2analysisA2areA2timeA2sensitive
IdentifyA2methodsA2useA2forA2analysisA2ofA2traceA2metalsA2-A2Ans--
•AtomicA2EmissionA2SpectroscopyA2(AES)