AANP ACTUAL EXAM 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◉ The most commonly prescribed medication for mild systemic lupus
erythematosus (SLE) is:
1. azathioprine (AZA).
2. belimumab (Benlysta).
3. ibuprofen (Advil).
4. cyclophosphamide (Cytoxan). Answer: ibuprofen (advil)
◉ The most common sign of cervical cancer is:
1. postcoital bleeding.
2. strong odor from vaginal discharge.
3. itching in the vaginal area.
4. molluscum contagiosum. Answer: postcoital bleeding
◉ The nurse practitioner prescribes amitriptyline (Elavil) for a patient
with neuropathic pain secondary to diabetes mellitus. On follow-up, the
patient complains of urine retention and dry mouth. The practitioner
would:
,1. discontinue amitriptyline and begin ibuprofen (Motrin).
2. refer to physical therapy.
3. start methocarbamol (Robaxin).
4. discontinue amitriptyline and begin gabapentin (Neurontin). Answer:
discontinue amitriptyline and begin gabapentin (neurontin)
◉ A 17-year-old male with rheumatoid arthritis is being treated with an
NSAID and omeprazole (Prilosec). The patient complains of headache,
abdominal pain, and gas. These symptoms are most likely:
1. associated with the omeprazole.
2. related to the underlying condition.
3. the result of the NSAID.
4. caused by viral gastroenteritis. Answer: associated with the
omeprazole
◉ The medication of choice for the initial treatment of juvenile
rheumatoid arthritis is:
1. acetaminophen.
2. prednisone.
3. aspirin.
,4. ibuprofen. Answer: ibuprofen
◉ A 12-year-old with sickle cell anemia has recently experienced a
sickle cell crisis and presents for a follow-up examination after a recent
hospitalization. It is most important to continue monitoring growth,
development, and:
1. white blood cell levels.
2. fecal occult blood test.
3. hemoglobin levels.
4. urine dipsticks. Answer: hemoglobin levels
◉ A 90-year-old female is brought to the clinic by her neighbor. She
states that everything is fine, but the nurse practitioner notes that she has
poor hygiene and bruises on her trunk. The neighbor is concerned that
the patient often has no money to buy food, despite income from social
security and a coal miner's pension. The nurse practitioner suspects
abuse. Which of the following is the nurse practitioner obligated to do
next?
1. Report the case to the proper authorities.
2. Tell the neighbor to check on the woman daily and report back.
3. Document the data and report the information to risk management.
4. Call the patient's family and inquire about the concerns. Answer:
report the case to proper authorities
, ◉ In most cases, the first manifestation of Alzheimer's disease is:
1. impaired judgment.
2. decrease in short-term memory.
3. disorientation in time and place.
4. decrease in long-term memory. Answer: decrease in short-term
memory
◉ The optimal treatment for latent tuberculosis is:
1. rifampin (Rifadin) for 5 months.
2. isoniazid (Nydrazid) for 9 months.
3. pyrazinamide for 6 months.
4. ethambutol for 6 months. Answer: osioniazid (nydrazid) for 9 months
◉ Unilateral spontaneous serous or serosanguineous discharge from a
single duct of a breast is most often caused by:
1. intraductal papilloma.
2. mucinous breast lesions.
3. Paget's disease.
4. ductal carcinoma in situ. Answer: intraductal papilloma
SOLUTIONS GRADED A+
◉ The most commonly prescribed medication for mild systemic lupus
erythematosus (SLE) is:
1. azathioprine (AZA).
2. belimumab (Benlysta).
3. ibuprofen (Advil).
4. cyclophosphamide (Cytoxan). Answer: ibuprofen (advil)
◉ The most common sign of cervical cancer is:
1. postcoital bleeding.
2. strong odor from vaginal discharge.
3. itching in the vaginal area.
4. molluscum contagiosum. Answer: postcoital bleeding
◉ The nurse practitioner prescribes amitriptyline (Elavil) for a patient
with neuropathic pain secondary to diabetes mellitus. On follow-up, the
patient complains of urine retention and dry mouth. The practitioner
would:
,1. discontinue amitriptyline and begin ibuprofen (Motrin).
2. refer to physical therapy.
3. start methocarbamol (Robaxin).
4. discontinue amitriptyline and begin gabapentin (Neurontin). Answer:
discontinue amitriptyline and begin gabapentin (neurontin)
◉ A 17-year-old male with rheumatoid arthritis is being treated with an
NSAID and omeprazole (Prilosec). The patient complains of headache,
abdominal pain, and gas. These symptoms are most likely:
1. associated with the omeprazole.
2. related to the underlying condition.
3. the result of the NSAID.
4. caused by viral gastroenteritis. Answer: associated with the
omeprazole
◉ The medication of choice for the initial treatment of juvenile
rheumatoid arthritis is:
1. acetaminophen.
2. prednisone.
3. aspirin.
,4. ibuprofen. Answer: ibuprofen
◉ A 12-year-old with sickle cell anemia has recently experienced a
sickle cell crisis and presents for a follow-up examination after a recent
hospitalization. It is most important to continue monitoring growth,
development, and:
1. white blood cell levels.
2. fecal occult blood test.
3. hemoglobin levels.
4. urine dipsticks. Answer: hemoglobin levels
◉ A 90-year-old female is brought to the clinic by her neighbor. She
states that everything is fine, but the nurse practitioner notes that she has
poor hygiene and bruises on her trunk. The neighbor is concerned that
the patient often has no money to buy food, despite income from social
security and a coal miner's pension. The nurse practitioner suspects
abuse. Which of the following is the nurse practitioner obligated to do
next?
1. Report the case to the proper authorities.
2. Tell the neighbor to check on the woman daily and report back.
3. Document the data and report the information to risk management.
4. Call the patient's family and inquire about the concerns. Answer:
report the case to proper authorities
, ◉ In most cases, the first manifestation of Alzheimer's disease is:
1. impaired judgment.
2. decrease in short-term memory.
3. disorientation in time and place.
4. decrease in long-term memory. Answer: decrease in short-term
memory
◉ The optimal treatment for latent tuberculosis is:
1. rifampin (Rifadin) for 5 months.
2. isoniazid (Nydrazid) for 9 months.
3. pyrazinamide for 6 months.
4. ethambutol for 6 months. Answer: osioniazid (nydrazid) for 9 months
◉ Unilateral spontaneous serous or serosanguineous discharge from a
single duct of a breast is most often caused by:
1. intraductal papilloma.
2. mucinous breast lesions.
3. Paget's disease.
4. ductal carcinoma in situ. Answer: intraductal papilloma
