Naloxone binds to the opioid receptor, preventing opioids from binding, therefore
preventing an effect. In this situation, the naloxone is a(n) ___ and the opioid is a(n) ___
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antagonist ; agonist
A dose of agonist occupies 30% of receptors and gives an effect of 50. According to
the occupancy theory, what would you expect from a dose that occupies 90% of
receptors?
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150
,Which of the following are only available as prescription drugs in the U.S.? Select all
that apply.
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Codeine
levothyroxine
Tadalafil
Drug A requires 15 µM to reach 50% of its maximum response while Drug B requires
50 µM to reach 50% of its maximum response. Which drug is more efficacy?
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Cannot tell
The majority of drug excretion occurs in which organ?
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Kidney
Which type of drug is most likely to be given orally?
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, Small molecule
Assuming the same lipophilicity and that all are neutrally charged (in reality these are
horrible assumptions), which drug would you expect to have the best membrane
permeability?
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Tylenol
Which branch of pharmacology studies how patients respond differently to drugs?
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Pharmacogenetics
For which of the following parts of translational research is patient involvement
critical? Choose all that apply.
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ALL:
Public Health
Basic Research
Pre-Clinical Research
Clinical Research
Clinical Implementation
preventing an effect. In this situation, the naloxone is a(n) ___ and the opioid is a(n) ___
Give this one a try later!
antagonist ; agonist
A dose of agonist occupies 30% of receptors and gives an effect of 50. According to
the occupancy theory, what would you expect from a dose that occupies 90% of
receptors?
Give this one a try later!
150
,Which of the following are only available as prescription drugs in the U.S.? Select all
that apply.
Give this one a try later!
Codeine
levothyroxine
Tadalafil
Drug A requires 15 µM to reach 50% of its maximum response while Drug B requires
50 µM to reach 50% of its maximum response. Which drug is more efficacy?
Give this one a try later!
Cannot tell
The majority of drug excretion occurs in which organ?
Give this one a try later!
Kidney
Which type of drug is most likely to be given orally?
Give this one a try later!
, Small molecule
Assuming the same lipophilicity and that all are neutrally charged (in reality these are
horrible assumptions), which drug would you expect to have the best membrane
permeability?
Give this one a try later!
Tylenol
Which branch of pharmacology studies how patients respond differently to drugs?
Give this one a try later!
Pharmacogenetics
For which of the following parts of translational research is patient involvement
critical? Choose all that apply.
Give this one a try later!
ALL:
Public Health
Basic Research
Pre-Clinical Research
Clinical Research
Clinical Implementation