Fundamentals of Chemotherapy Immunotherapy
Administration Exam with All Correct & 100% Verified
Answers |Latest Update| Already Graded A+
Hematologic cancer (blood cancer) ✔Correct Answer--cancer that begins in bone marrow or
immune system cells.
-Ex: leukemia, lymphoma, multiple myeloma
Leukemia ✔Correct Answer-cancer starts in blood-forming tissues like bone marrow
-causes lots of abnormal blood cells to be produced and enter bloodstream
Lymphoma ✔Correct Answer--cancer that begins in immune system (WBC=lymphocytes)
-hodgkin and non-hodgkins
-B lymphocytes (B cells) - make antibodies (bacteria and viruses, most common lymphoma
-T lymphocytes (T cells) - boost/slow immune, destroy germs and abnormal cells
Hodgkin lymphoma ✔Correct Answer-Reed-Sternberg cell (cancer cells in classic)
-typically starts in B cells
Non-Hodgkin's Lymphoma ✔Correct Answer--large, diverse group of cancers in immune system
cells
-indolent (slow growing) or aggressive (fast)
Myeloma ✔Correct Answer-Cancer in plasma cells (WBC that produce antibodies)
Chemotherapy ✔Correct Answer-All antineoplastic agents used to treat cancer, given through oral
and parenteral routes or other routes as specified in the standard, not including hormonal therapies.
Who can order chemotherapy? ✔Correct Answer-Written and signed by licensed independent
practitioners (MD/DO, PA, Oncology NP)
Can you use verbal orders for chemotherapy? ✔Correct Answer-NO! Only when holding/stopping
admin.
Who can mix Chemotherapy? ✔Correct Answer-Pharmacist, Pharmacy tech, MD/DO, qualified RN
Who can administer chemotherapy? ✔Correct Answer-Registered Nurses with specialized
education, prep and training. See specific state laws and statutes
How often is chemo competency reassessed> ✔Correct Answer-Annual continuing ed and
competency assessment is recommended
What is the dose verification process? ✔Correct Answer--confirm plan with patient
-two practitioners verify: drug name, dose, volume, rate, route, expiration date, appearance
-document verification in chart
What PPE is required for IV Chemotherapy? ✔Correct Answer--Gloves: two pairs, HD tested
-Gown: disposable, back closed, long sleeved
, -Respirator: NIOSH approved
-Eye & Face: face shield/mask
Neoadjuvant therapy (tumor burden) ✔Correct Answer-Chemo BEFORE primary treatment
(common in breast and colon)
Adjuvant therapy ✔Correct Answer-Chemo AFTER primary treatment (common in solid tumor)
Bone Marrow ✔Correct Answer-soft, sponge-like tissue in center of most bones, produce WBC,
RBC, and platelets.
Myelosuppression ✔Correct Answer-bone marrow activity is decreased, causing less RBC, WBC
and Platelets.
Myeloablation ✔Correct Answer-severe myelosuppression
Induction phase ✔Correct Answer-initial phase, typically in hospital, intended myelosuppression
Consolidation phase (intensification/postremission therapy) ✔Correct Answer-after successful
induction, kills cancer cells left in body (ex radiation, stem cell transplant)
Synergy ✔Correct Answer-when one chemo drug helps another work better at the same time
Complete response ✔Correct Answer-no identifiable cancer present for at least one month or
longer
Partial response ✔Correct Answer-Measurable tumor reduced by 50% for at least one month with
no new tumors
Stable disease ✔Correct Answer-Tumor size reduced by less than 50% or less than 25% increase in
growth
Progressive disease ✔Correct Answer-tumor growth more than 25% or new cancer
What are the phases of the cell cycle? ✔Correct Answer--G1 phase
-S phase
-G2 phase
-M phase
What happens in G1 phase? ✔Correct Answer-The cell increases in size and prepares to replicate
its DNA.
What do chemo drugs do to target S phase? ✔Correct Answer-Prevent cell from making DNA
and/or RNA (replicating)
(ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines (hydroxyurea))
What do chemo drugs do to target G2 phase? ✔Correct Answer-Cells prepare to divide, chemo
drugs stop development of elements needed for cell division
(ex: topoisomerase I and II inhibitors, bleomycin)
Administration Exam with All Correct & 100% Verified
Answers |Latest Update| Already Graded A+
Hematologic cancer (blood cancer) ✔Correct Answer--cancer that begins in bone marrow or
immune system cells.
-Ex: leukemia, lymphoma, multiple myeloma
Leukemia ✔Correct Answer-cancer starts in blood-forming tissues like bone marrow
-causes lots of abnormal blood cells to be produced and enter bloodstream
Lymphoma ✔Correct Answer--cancer that begins in immune system (WBC=lymphocytes)
-hodgkin and non-hodgkins
-B lymphocytes (B cells) - make antibodies (bacteria and viruses, most common lymphoma
-T lymphocytes (T cells) - boost/slow immune, destroy germs and abnormal cells
Hodgkin lymphoma ✔Correct Answer-Reed-Sternberg cell (cancer cells in classic)
-typically starts in B cells
Non-Hodgkin's Lymphoma ✔Correct Answer--large, diverse group of cancers in immune system
cells
-indolent (slow growing) or aggressive (fast)
Myeloma ✔Correct Answer-Cancer in plasma cells (WBC that produce antibodies)
Chemotherapy ✔Correct Answer-All antineoplastic agents used to treat cancer, given through oral
and parenteral routes or other routes as specified in the standard, not including hormonal therapies.
Who can order chemotherapy? ✔Correct Answer-Written and signed by licensed independent
practitioners (MD/DO, PA, Oncology NP)
Can you use verbal orders for chemotherapy? ✔Correct Answer-NO! Only when holding/stopping
admin.
Who can mix Chemotherapy? ✔Correct Answer-Pharmacist, Pharmacy tech, MD/DO, qualified RN
Who can administer chemotherapy? ✔Correct Answer-Registered Nurses with specialized
education, prep and training. See specific state laws and statutes
How often is chemo competency reassessed> ✔Correct Answer-Annual continuing ed and
competency assessment is recommended
What is the dose verification process? ✔Correct Answer--confirm plan with patient
-two practitioners verify: drug name, dose, volume, rate, route, expiration date, appearance
-document verification in chart
What PPE is required for IV Chemotherapy? ✔Correct Answer--Gloves: two pairs, HD tested
-Gown: disposable, back closed, long sleeved
, -Respirator: NIOSH approved
-Eye & Face: face shield/mask
Neoadjuvant therapy (tumor burden) ✔Correct Answer-Chemo BEFORE primary treatment
(common in breast and colon)
Adjuvant therapy ✔Correct Answer-Chemo AFTER primary treatment (common in solid tumor)
Bone Marrow ✔Correct Answer-soft, sponge-like tissue in center of most bones, produce WBC,
RBC, and platelets.
Myelosuppression ✔Correct Answer-bone marrow activity is decreased, causing less RBC, WBC
and Platelets.
Myeloablation ✔Correct Answer-severe myelosuppression
Induction phase ✔Correct Answer-initial phase, typically in hospital, intended myelosuppression
Consolidation phase (intensification/postremission therapy) ✔Correct Answer-after successful
induction, kills cancer cells left in body (ex radiation, stem cell transplant)
Synergy ✔Correct Answer-when one chemo drug helps another work better at the same time
Complete response ✔Correct Answer-no identifiable cancer present for at least one month or
longer
Partial response ✔Correct Answer-Measurable tumor reduced by 50% for at least one month with
no new tumors
Stable disease ✔Correct Answer-Tumor size reduced by less than 50% or less than 25% increase in
growth
Progressive disease ✔Correct Answer-tumor growth more than 25% or new cancer
What are the phases of the cell cycle? ✔Correct Answer--G1 phase
-S phase
-G2 phase
-M phase
What happens in G1 phase? ✔Correct Answer-The cell increases in size and prepares to replicate
its DNA.
What do chemo drugs do to target S phase? ✔Correct Answer-Prevent cell from making DNA
and/or RNA (replicating)
(ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines (hydroxyurea))
What do chemo drugs do to target G2 phase? ✔Correct Answer-Cells prepare to divide, chemo
drugs stop development of elements needed for cell division
(ex: topoisomerase I and II inhibitors, bleomycin)
