BIO 325 Final Exam Review Questions and
Answers (100% Correct Answers) Already
Graded A+
Ribosomal genes are transcribed by RNA Polymerase ___ [
Ans: ] I
In Prokaryotes, cluster of genes can be regulated together.
This cluster of genes is called an ____ [ Ans: ] operon
E. coli's heat shock response is controlled by alternative
______ factors that recognize different promoter
sequences. [ Ans: ] sigma
"Certain covalent modifications of Histone can dictate the
fate of gene expression at given loci" is referred as _____
_____ hypothesis. [ Ans: ] Histone Code
p53 can induce programmed cell death if the damage
cannot be repaired through a process called ______ . [ Ans:
] apoptosis
Generally speaking, cancer is due to abnormal or
uncontrolled _____ division [ Ans: ] cell
XXY male would have ____ Barr body(ies) [ Ans: ] 1
In an old view of heredity, __________ inheritance assumes
that parental traits become mixed and forever changed in
offspring. [ Ans: ] blending
,A short single-stranded piece of DNA that is labeled and
used in hybridization experiments is called a(n) ________ [
Ans: ] probe
T/F: Genotype frequency can change until the population
comes to equilibrium. [ Ans: ] True
T/F: Trimethylation at Histone H3 Lys 27 usually
associated with transcriptionally repressed chromatins [
Ans: ] True
T/F: After meiosis I, chromosome set number is n. [ Ans: ]
True
T/F: High concentration of Glucose is necessary for the
maximum induction of Lac operon genes. [ Ans: ] False
T/F: A man with blood type "A," whose father was blood
type "O," married a woman of blood type "B" whose mother
was blood type "O." Children of this couple can have all
possible blood types [ Ans: ] True
T/F: HIV contains reverse transcriptase. [ Ans: ] True
T/F: cDNAs from eukaryotic organisms contain promoter
region. [ Ans: ] False
T/F: The map of a chromosome interval is A--10 m.u.--B--
40 m.u.--C. From the cross Abc/aBC × abc/abc, you
observed 10 double crossovers from 1000 progeny. In this
case, interference is 0.5 [ Ans: ] False
,T/F: Population at Hardy-Weinberg equilibrium assumes
that there is no new mutation over generations. [ Ans: ]
True
T/F: Nimblegen array uses photo-activating building
blocks to construct DNA array on the slide. [ Ans: ] True
If grandparents are heterozygous for the trait, what is the
probability that a child in question would NOT have the
trait (disease).
A. 1/4
B. 3/4
C. 1/3
D. 2/3 [ Ans: ] D (2/3)
What technique would be used to best study a phenocopy?
A. RNAi
B. Transgene
C. Isolation of mutations
D. QTL mapping analysis
E. Microarray [ Ans: ] A (RNAi)
In eukaryotes, transcriptional activity is low when:
, A. DNA is hypermethylated.
B. Histone is hyperacetylated.
C. Histone H3 Lys 4 is methylated. D. Histone H3 Lys 36 is
methylated E. none of the above. [ Ans: ] A (DNA is
hypermethylated)
Which of the following is property of Enhancer?
A. it is one of tran-acting components in gene regulation.
B. it is always located immediate 5' end of a gene.
C. it is always located immediate 3' end of a gene.
D. its orientation is not important. [ Ans: ] D (its
orientation is not important)
The Rb activity is regulated by
A. its phosphorylation state.
B. its methylation level
C. cyclin A.
D. E2F
E. its polyA tail. [ Ans: ] A (its phosphorylation state)
In humans, brachydactyly is a dominant condition. Six
thousand four hundred people in a population of 10,000
Answers (100% Correct Answers) Already
Graded A+
Ribosomal genes are transcribed by RNA Polymerase ___ [
Ans: ] I
In Prokaryotes, cluster of genes can be regulated together.
This cluster of genes is called an ____ [ Ans: ] operon
E. coli's heat shock response is controlled by alternative
______ factors that recognize different promoter
sequences. [ Ans: ] sigma
"Certain covalent modifications of Histone can dictate the
fate of gene expression at given loci" is referred as _____
_____ hypothesis. [ Ans: ] Histone Code
p53 can induce programmed cell death if the damage
cannot be repaired through a process called ______ . [ Ans:
] apoptosis
Generally speaking, cancer is due to abnormal or
uncontrolled _____ division [ Ans: ] cell
XXY male would have ____ Barr body(ies) [ Ans: ] 1
In an old view of heredity, __________ inheritance assumes
that parental traits become mixed and forever changed in
offspring. [ Ans: ] blending
,A short single-stranded piece of DNA that is labeled and
used in hybridization experiments is called a(n) ________ [
Ans: ] probe
T/F: Genotype frequency can change until the population
comes to equilibrium. [ Ans: ] True
T/F: Trimethylation at Histone H3 Lys 27 usually
associated with transcriptionally repressed chromatins [
Ans: ] True
T/F: After meiosis I, chromosome set number is n. [ Ans: ]
True
T/F: High concentration of Glucose is necessary for the
maximum induction of Lac operon genes. [ Ans: ] False
T/F: A man with blood type "A," whose father was blood
type "O," married a woman of blood type "B" whose mother
was blood type "O." Children of this couple can have all
possible blood types [ Ans: ] True
T/F: HIV contains reverse transcriptase. [ Ans: ] True
T/F: cDNAs from eukaryotic organisms contain promoter
region. [ Ans: ] False
T/F: The map of a chromosome interval is A--10 m.u.--B--
40 m.u.--C. From the cross Abc/aBC × abc/abc, you
observed 10 double crossovers from 1000 progeny. In this
case, interference is 0.5 [ Ans: ] False
,T/F: Population at Hardy-Weinberg equilibrium assumes
that there is no new mutation over generations. [ Ans: ]
True
T/F: Nimblegen array uses photo-activating building
blocks to construct DNA array on the slide. [ Ans: ] True
If grandparents are heterozygous for the trait, what is the
probability that a child in question would NOT have the
trait (disease).
A. 1/4
B. 3/4
C. 1/3
D. 2/3 [ Ans: ] D (2/3)
What technique would be used to best study a phenocopy?
A. RNAi
B. Transgene
C. Isolation of mutations
D. QTL mapping analysis
E. Microarray [ Ans: ] A (RNAi)
In eukaryotes, transcriptional activity is low when:
, A. DNA is hypermethylated.
B. Histone is hyperacetylated.
C. Histone H3 Lys 4 is methylated. D. Histone H3 Lys 36 is
methylated E. none of the above. [ Ans: ] A (DNA is
hypermethylated)
Which of the following is property of Enhancer?
A. it is one of tran-acting components in gene regulation.
B. it is always located immediate 5' end of a gene.
C. it is always located immediate 3' end of a gene.
D. its orientation is not important. [ Ans: ] D (its
orientation is not important)
The Rb activity is regulated by
A. its phosphorylation state.
B. its methylation level
C. cyclin A.
D. E2F
E. its polyA tail. [ Ans: ] A (its phosphorylation state)
In humans, brachydactyly is a dominant condition. Six
thousand four hundred people in a population of 10,000
