TEST BANK TO ACCOMPANY PSYCHOPHARMACOLOGY, THIRD EDITION MEYER • QUENZER

TEST BANK TO ACCOMPANY PSYCHOPHARMACOLOGY, THIRD EDITION
MEYER • QUENZER

, Chapter c1: cPrinciples cof cPharmacology

Multiple cChoice

1. refer(s) cto cspecific cmolecular cchanges cthat coccur cwhen ca cdrug cbinds
cto ca cparticular ctarget csite cor creceptor, cwhile are cthe cresulting cwidespread
calterations cin cfunction.
a. Drug caction; ctherapeutic ceffects
b. Side ceffects; cdrug ceffects
c. Therapeutic ceffects; cside ceffects
d. Drug caction; cdrug ceffects
Answer: cd
Textbook cReference: cPharmacology: cThe cScience cof cDrug cAction

2. After cdrug cadministration chas coccurred, cthe camount cof cdrug cin cthe cblood cthat cis
cfree cto cbind cat cspecific ctarget csites cis creferred cto cas
a. the ctherapeutic cdose.
b. first-pass ceffects.
c. bioavailability.
d. ED50.
Answer: cc
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

3. The cspecific cmolecular cchanges cthat coccur cwhen ca cdrug cbinds cto ca cparticular
ctarget csite cor creceptor care creferred cto cas
a. drug ceffects.
b. drug caction.
c. side ceffects.
d. placebo ceffects.
Answer: cb
Textbook cReference: cPharmacology: cThe cScience cof cDrug cAction

4. Which cof cthe cfollowing cis cnot ca cpossible cexplanation cfor cplacebo ceffects?
a. Pavlovian cconditioning
b. Genetic cvariation
c. Drug ccompetition
d. Expectation cof coutcome
Answer: cc
Textbook cReference: cPharmacology: cThe cScience cof cDrug cAction




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,5. The administration cof coxytocin chas cbeen cproposed cas ca ctreatment cfor cautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: cc
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

6. Which cfactor cdoes cnot caffect cthe cpharmacokinetics cof ca cdrug?
a. Route cof cadministration
b. Lipid csolubility
c. Depot cbinding
d. Drug caction
Answer: cd
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

7. First-pass cmetabolism coccurs cwhen cdrugs care ctaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: ca
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

8. The carea cpostrema cis cone carea cin cthe cbrain cwhere cthe is cnot ccomplete.
a. cerebrospinal cfluid
b. blood–brain cbarrier
c. choroid cplexus
d. phospholipid cmembrane
Answer: cb
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

9. First-pass cmetabolism coccurs cwith corally cadministered cdrugs cbecause
a. their cabsorption cis cslowed cby cfood.
b. drugs cabsorbed cinto cthe cbloodstream cfrom cthe cstomach cgo cto cthe cliver con cthe
cway cto cgeneral ccirculation.
c. drugs cmust cfirst csurvive cthe cacidic cenvironment cof cthe cstomach.
d. salivary cenzymes cin cthe cmouth cbegin cthe cprocess cof cmetabolism.
Answer: cb
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

10. Toxic csubstances cin cthe cblood ctrigger ca cvomiting cresponse cby cactivating cthe
a. blood–brain cbarrier.
b. choroid cplexus.
c. area cpostrema.
d. median ceminence.



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, Answer: cc
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

11. Drugs cadministered c_ have cthe cmost crapid conset cof caction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: cd
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

12. Ionization cof ca cdrug cdepends con cthe of cthe csolution cand cthe of
cthe cdrug.
a. pH; cpKa
b. pKa; cpH
c. concentration; clipid csolubility
d. pH; cconcentration
Answer: ca
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

13. The cabsorption cof ca cdrug cdepends con call cof cthe cfollowing cexcept
a. lipid csolubility.
b. ionization.
c. body ctemperature.
d. the cconcentration cof cthe cdrug.
Answer: cc
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

14. Drugs cthat care should cbe cavoided cby cwomen cof cchildbearing cage.
a. teratogenic
b. able cto ccross cthe cplacental cbarrier
c. psychoactive
d. highly clipid-soluble
Answer: ca
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

15. Agents cthat cinduce cdevelopmental cabnormalities cin ca cfetus care cknown cas
a. psychoactive cdrugs.
b. illicit cdrugs.
c. teratogens.
d. placental cdrugs.
Answer: cc
Textbook cReference: cPharmacokinetic cFactors cDetermining cDrug cAction

16. Depot cbinding cis csaid cto coccur cwhen cdrugs
a. bind cto ctheir ctarget csites.



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