HESI PHARMACOLOGY EXAM FULL
QUESTIONS AND ANSWERS 2026 GRADED A+
◉ 2. Answer: A 67-year-old client has tested positive for influenza A.
The client also has asthma. Which drug would the nurse recommend
be avoided in this client?
1 Ribavirin
2 Zanamivir
3 Oseltamivir
4 Amantadine
◉ 1. Answer: Which first line medication would the nurse state is
used to treat anaphylactic reactions?
1 Epinephrine
2 Norepinephrine
3 Dexamethasone
4 Diphenhydramine
◉ 1. Answer: A mother complains that her child's teeth have become
yellow in color. With prolonged use, which medication may be
responsible for the child's condition?
1 Tetracycline
,2 Promethazine
3 Chloramphenicol
4 Fluoroquinolones
◉ 2,3,6. Answer: What are the desired outcomes that the nurse
expects when administering a nonsteroidal antiinflammatory drug
(NSAID)? Select all that apply
1 Diuresis
2 Pain relief
3 Antipyresis
4 Bronchodilation
5 Anticoagulation
6 Reduced inflammation
◉ 2. Answer: A client with tuberculosis is started on a chemotherapy
protocol that includes rifampin. The nurse evaluates that the
teaching about rifampin is effective when the client makes which
statement?
1 "I need to drink a lot of fluid while I take this medication."
2 "I can expect my urine to turn orange from this medication."
3 "I should have my hearing tested while I take this medication."
4 "I might get a skin rash because it is an expected side effect of this
medication.
,◉ 1. Answer: Which statement regarding treatment with interferon
indicates that the client understands the nurse's teaching?
1 "I will drink 2 to 3 quarts (2 to 3 liters) of fluid a day."
2 "Any reconstituted solution must be discarded in 1 week."
3 "I can continue driving my car as long as I have the stamina."
4 "While taking this medicine I should be able to continue my usual
activity."
◉ 2. Answer: A nurse administers the drug desmopressin acetate
(DDAVP) to a client with diabetes insipidus. What should the nurse
monitor to evaluate the effectiveness of the drug?
1 Arterial blood pH
2 Intake and output
3 Fasting serum glucose
4 Pulse and respiratory rates
◉ 1. Answer: A client will be taking nitrofurantoin 50 mg orally
every evening at home to manage recurrent urinary tract infections.
What instructions should the nurse give to the client?
1 Increase the intake of fluids.
2 Strain the urine for crystals and stones.
3 Stop the drug if urinary output increases.
, 4 Maintain the exact time schedule for taking the drug
◉ 3. Answer: A client admitted to the hospital with a diagnosis of
chronic obstructive pulmonary disease has received a prescription
for a medication that is delivered via a nebulizer. When teaching
about use of the nebulizer, the nurse should teach the client to do
what?
1 Hold the breath while spraying the medication into the mouth.
2 Position the lips loosely around the mouthpiece and take rapid,
shallow breaths.
3 Seal the lips around the mouthpiece and breathe in and out, taking
slow, deep breaths.
4 Inhale the medication from the nebulizer, remove the mouthpiece
from the mouth, and then exhale.
◉ 4. Answer: A client is diagnosed with pulmonary tuberculosis, and
the healthcare provider prescribes a combination of rifampin and
isoniazid. The nurse evaluates that the teaching regarding the drug
is effective when the client reports which action as most important?
1 "Report any changes in vision."
2 "Take the medicine with my meals."
3 "Call my doctor if my urine or tears turn red-orange."
4 "Continue taking the medicine even after I feel better.
QUESTIONS AND ANSWERS 2026 GRADED A+
◉ 2. Answer: A 67-year-old client has tested positive for influenza A.
The client also has asthma. Which drug would the nurse recommend
be avoided in this client?
1 Ribavirin
2 Zanamivir
3 Oseltamivir
4 Amantadine
◉ 1. Answer: Which first line medication would the nurse state is
used to treat anaphylactic reactions?
1 Epinephrine
2 Norepinephrine
3 Dexamethasone
4 Diphenhydramine
◉ 1. Answer: A mother complains that her child's teeth have become
yellow in color. With prolonged use, which medication may be
responsible for the child's condition?
1 Tetracycline
,2 Promethazine
3 Chloramphenicol
4 Fluoroquinolones
◉ 2,3,6. Answer: What are the desired outcomes that the nurse
expects when administering a nonsteroidal antiinflammatory drug
(NSAID)? Select all that apply
1 Diuresis
2 Pain relief
3 Antipyresis
4 Bronchodilation
5 Anticoagulation
6 Reduced inflammation
◉ 2. Answer: A client with tuberculosis is started on a chemotherapy
protocol that includes rifampin. The nurse evaluates that the
teaching about rifampin is effective when the client makes which
statement?
1 "I need to drink a lot of fluid while I take this medication."
2 "I can expect my urine to turn orange from this medication."
3 "I should have my hearing tested while I take this medication."
4 "I might get a skin rash because it is an expected side effect of this
medication.
,◉ 1. Answer: Which statement regarding treatment with interferon
indicates that the client understands the nurse's teaching?
1 "I will drink 2 to 3 quarts (2 to 3 liters) of fluid a day."
2 "Any reconstituted solution must be discarded in 1 week."
3 "I can continue driving my car as long as I have the stamina."
4 "While taking this medicine I should be able to continue my usual
activity."
◉ 2. Answer: A nurse administers the drug desmopressin acetate
(DDAVP) to a client with diabetes insipidus. What should the nurse
monitor to evaluate the effectiveness of the drug?
1 Arterial blood pH
2 Intake and output
3 Fasting serum glucose
4 Pulse and respiratory rates
◉ 1. Answer: A client will be taking nitrofurantoin 50 mg orally
every evening at home to manage recurrent urinary tract infections.
What instructions should the nurse give to the client?
1 Increase the intake of fluids.
2 Strain the urine for crystals and stones.
3 Stop the drug if urinary output increases.
, 4 Maintain the exact time schedule for taking the drug
◉ 3. Answer: A client admitted to the hospital with a diagnosis of
chronic obstructive pulmonary disease has received a prescription
for a medication that is delivered via a nebulizer. When teaching
about use of the nebulizer, the nurse should teach the client to do
what?
1 Hold the breath while spraying the medication into the mouth.
2 Position the lips loosely around the mouthpiece and take rapid,
shallow breaths.
3 Seal the lips around the mouthpiece and breathe in and out, taking
slow, deep breaths.
4 Inhale the medication from the nebulizer, remove the mouthpiece
from the mouth, and then exhale.
◉ 4. Answer: A client is diagnosed with pulmonary tuberculosis, and
the healthcare provider prescribes a combination of rifampin and
isoniazid. The nurse evaluates that the teaching regarding the drug
is effective when the client reports which action as most important?
1 "Report any changes in vision."
2 "Take the medicine with my meals."
3 "Call my doctor if my urine or tears turn red-orange."
4 "Continue taking the medicine even after I feel better.
