CMAN 272 Exam 2 UPDATED ACTUAL
QUESTIONS AND CORRECT ANSWERS
to be diagnosed with MDD, you need one of two symptoms - CORRECT
ANSWERS depressed mood; apathy/loss of interest
to be diagnosed with MDD, you need 4/7 symptoms - CORRECT
ANSWERS weight/appetite changes; sleep disturbances; psychomotor; fatigue;
worthlessness; executive dysfunction; suicidal ideation
pharmacological management of MDD - CORRECT ANSWERS SSRI, NDRI, SNRI,
TCAs, MAOI
SSRI MOA - CORRECT ANSWERS selective serotonin reuptake inhibitor; increases
serotonin in body
NDRI MOA - CORRECT ANSWERS norepinephrine dopamine reuptake inhibitor
SSRI use - CORRECT ANSWERS antidepressant, anxiety (first line)
NRDI use - CORRECT ANSWERS depression, smoking cessation
NRDI SE - CORRECT ANSWERS weight loss, reduced appetite, insomnia, elevated BP
SSRI SE - CORRECT ANSWERS GI upset, n/v, sexual dysfunction
SNRI MOA - CORRECT ANSWERS Serotonin norepinephrine reuptake inhibitor
SNRI uses - CORRECT ANSWERS depression; somatic pain; co-occuring pain disorder
, SNRI SE - CORRECT ANSWERS GI upset, n/v, fatigue (take at night), weight loss,
sexual dysfunction
Trazodone, Remeron - CORRECT ANSWERS depression; used when patient has sleep
dysfunction (initiating sleep)
Tricyclic (TCAs) MOA - CORRECT ANSWERS increases all monoamines
TCA SE - CORRECT ANSWERS weight gain, dry mouth, sedation, cardiac effects
MAOI Example - CORRECT ANSWERS Nardil
MAOI consideration - CORRECT ANSWERS tyramine free diet
MAOI major issue - CORRECT ANSWERS hypertensive crisis
MAOI SE - CORRECT ANSWERS n/v, muscle twitching/hyperreflexia, headache,
hypotension, ALT/AST elevation (affects liver)
serotonin syndrome SE - CORRECT ANSWERS restless, agitation, hyper-reflexia,
hyperthermia, tremor, diaphoresis, diarrhea, headache, insomnia
Discontinuation syndrom SE - CORRECT ANSWERS lethargy, fatigue, myalgia (joint
pain), anxiety, emotionally lability
ECT - CORRECT ANSWERS induces seizures to treat depression
ECT SE - CORRECT ANSWERS headache, confusion, ST memory loss
QUESTIONS AND CORRECT ANSWERS
to be diagnosed with MDD, you need one of two symptoms - CORRECT
ANSWERS depressed mood; apathy/loss of interest
to be diagnosed with MDD, you need 4/7 symptoms - CORRECT
ANSWERS weight/appetite changes; sleep disturbances; psychomotor; fatigue;
worthlessness; executive dysfunction; suicidal ideation
pharmacological management of MDD - CORRECT ANSWERS SSRI, NDRI, SNRI,
TCAs, MAOI
SSRI MOA - CORRECT ANSWERS selective serotonin reuptake inhibitor; increases
serotonin in body
NDRI MOA - CORRECT ANSWERS norepinephrine dopamine reuptake inhibitor
SSRI use - CORRECT ANSWERS antidepressant, anxiety (first line)
NRDI use - CORRECT ANSWERS depression, smoking cessation
NRDI SE - CORRECT ANSWERS weight loss, reduced appetite, insomnia, elevated BP
SSRI SE - CORRECT ANSWERS GI upset, n/v, sexual dysfunction
SNRI MOA - CORRECT ANSWERS Serotonin norepinephrine reuptake inhibitor
SNRI uses - CORRECT ANSWERS depression; somatic pain; co-occuring pain disorder
, SNRI SE - CORRECT ANSWERS GI upset, n/v, fatigue (take at night), weight loss,
sexual dysfunction
Trazodone, Remeron - CORRECT ANSWERS depression; used when patient has sleep
dysfunction (initiating sleep)
Tricyclic (TCAs) MOA - CORRECT ANSWERS increases all monoamines
TCA SE - CORRECT ANSWERS weight gain, dry mouth, sedation, cardiac effects
MAOI Example - CORRECT ANSWERS Nardil
MAOI consideration - CORRECT ANSWERS tyramine free diet
MAOI major issue - CORRECT ANSWERS hypertensive crisis
MAOI SE - CORRECT ANSWERS n/v, muscle twitching/hyperreflexia, headache,
hypotension, ALT/AST elevation (affects liver)
serotonin syndrome SE - CORRECT ANSWERS restless, agitation, hyper-reflexia,
hyperthermia, tremor, diaphoresis, diarrhea, headache, insomnia
Discontinuation syndrom SE - CORRECT ANSWERS lethargy, fatigue, myalgia (joint
pain), anxiety, emotionally lability
ECT - CORRECT ANSWERS induces seizures to treat depression
ECT SE - CORRECT ANSWERS headache, confusion, ST memory loss
