PCB 3233 Exam 5 Questions and Answers
2025 A+
When IgE binds to a mast cell, is the Fc region facing
towards or away from the mast cell?
Towards
Fc-receptors can lead to
Effector function or movement
ex. phagocytosis (effector function)
Eosinophils can be
phagocytic or release granules. Its more likely to release
granules
When the baby is born does it have more IgG or less
IgG than the mother?
Neither, it comes with the same concentration of IgG as
the mother
Passive vs. Active Immunity
Main question: Did the person make the antibodies?
-If yes, then its active immunity
-If no, then its passive Immunity
True or False? Vaccination is an example of passive
immunity
False, because antigens are being injected which creates
a primary adaptive immune response. This means that
you are making the antibodies.
Can a booster of IgGs be given to a child after birth?
,No
After a child is born, IgG decreases up until how old?
6 months, which is when it makes its own Antibodies
What is the primary goal with Ab neutralization?
Stopping bacteria/pathogen from binding to your epithelial
cells.
Fc Receptors
-Deliver Ab to anatomical sites
-Link bound Ag to molecules or cells that will effect it's
destruction
-These cells carry Fc receptors (Examples: macrophages
and neutrophils).
Plasma Sickness
Antibodies attack proteins in the serum from inoculation of
another animal's blood.
IgG binds to what receptor of effector cells?
Fc-y(gamma) receptors
ADCC (antibody-dependent cell-mediated cytotoxicity)
NK cells can be activated by Antibodies
C1R and C1S
have protease activity
C3 convertase of classical pathway
C4b2a
C3 convertase of alternative pathway
C3bBb
True or False? C4b binds covalently to pathogen
True.
C3b binds to
, CR1 which leads to phagocytosis
C3b is an
opsonin
C5 convertase of the classical pathway
C4b2a3b
C5 convertase of alternative pathway
C3b2Bb
True or False? iC3b can become a C3 convertase?
Falso
iC3b binds to
CR3 and CR4
C3d binds to
CR2
iC3b is cut into becoming?
C3d
C3a and C5a are
Chemotactic and Anaphylatoxin
What complement components are utilized in the
Classical pathway?
C1-C9
What complement components are utilized in the
Alternative Pathway?
C3,C5-C9, Factor B and Factor D
systemic immune system is known as
Reactive because there is:
-Recognition
-Inflammation
-Adaptive Immune response
2025 A+
When IgE binds to a mast cell, is the Fc region facing
towards or away from the mast cell?
Towards
Fc-receptors can lead to
Effector function or movement
ex. phagocytosis (effector function)
Eosinophils can be
phagocytic or release granules. Its more likely to release
granules
When the baby is born does it have more IgG or less
IgG than the mother?
Neither, it comes with the same concentration of IgG as
the mother
Passive vs. Active Immunity
Main question: Did the person make the antibodies?
-If yes, then its active immunity
-If no, then its passive Immunity
True or False? Vaccination is an example of passive
immunity
False, because antigens are being injected which creates
a primary adaptive immune response. This means that
you are making the antibodies.
Can a booster of IgGs be given to a child after birth?
,No
After a child is born, IgG decreases up until how old?
6 months, which is when it makes its own Antibodies
What is the primary goal with Ab neutralization?
Stopping bacteria/pathogen from binding to your epithelial
cells.
Fc Receptors
-Deliver Ab to anatomical sites
-Link bound Ag to molecules or cells that will effect it's
destruction
-These cells carry Fc receptors (Examples: macrophages
and neutrophils).
Plasma Sickness
Antibodies attack proteins in the serum from inoculation of
another animal's blood.
IgG binds to what receptor of effector cells?
Fc-y(gamma) receptors
ADCC (antibody-dependent cell-mediated cytotoxicity)
NK cells can be activated by Antibodies
C1R and C1S
have protease activity
C3 convertase of classical pathway
C4b2a
C3 convertase of alternative pathway
C3bBb
True or False? C4b binds covalently to pathogen
True.
C3b binds to
, CR1 which leads to phagocytosis
C3b is an
opsonin
C5 convertase of the classical pathway
C4b2a3b
C5 convertase of alternative pathway
C3b2Bb
True or False? iC3b can become a C3 convertase?
Falso
iC3b binds to
CR3 and CR4
C3d binds to
CR2
iC3b is cut into becoming?
C3d
C3a and C5a are
Chemotactic and Anaphylatoxin
What complement components are utilized in the
Classical pathway?
C1-C9
What complement components are utilized in the
Alternative Pathway?
C3,C5-C9, Factor B and Factor D
systemic immune system is known as
Reactive because there is:
-Recognition
-Inflammation
-Adaptive Immune response
