NR507 Advanced Pathophysiology
MidTerm
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Terms in this set (55)
, Type 1: Allergic reaction, Mediated by IgE,
Inflammation due to mast cell degranulation
Local symptoms:
-itching
-rash
Hypersensitivity: Type
Systemic symptoms:
1
-wheezing
Most dangerous = anaphylactic reaction
systemic response of hypotension, severe
bronchoconstriction
Main treatment: epinephrine reverses the
effects
, Type 2: Cytotoxic reaction; tissue specific (ex:
thyroid tissue)
Macrophages are the primary effectors cells
involved
Can cause tissue damage or alter function
Hypersensitivity: Type
Grave's disease (hyperthyroidism) - example of
2
altering thyroid function, but does not destroy
thyroid tissue
Incompatible blood type- example of
cell/tissue damage that occurs; severe
transfusion reaction occurs and the transfused
erythrocytes are destroyed by agglutination
or complement-mediated lysis.
, Type 1 Hypersensitivity
Organ Specific
Antibody binds to the antigen on the cell
surface
Type 1
Hypersensitivity VS.
Type 2 Hypersensitivity
Type 2
Not Organ Specific
Hypersensitivity
Antibody binds to the soluble antigen outside
the cell surface that was released into the
blood or body fluids, and the complex is then
deposited in the tissues
MidTerm
Save
Terms in this set (55)
, Type 1: Allergic reaction, Mediated by IgE,
Inflammation due to mast cell degranulation
Local symptoms:
-itching
-rash
Hypersensitivity: Type
Systemic symptoms:
1
-wheezing
Most dangerous = anaphylactic reaction
systemic response of hypotension, severe
bronchoconstriction
Main treatment: epinephrine reverses the
effects
, Type 2: Cytotoxic reaction; tissue specific (ex:
thyroid tissue)
Macrophages are the primary effectors cells
involved
Can cause tissue damage or alter function
Hypersensitivity: Type
Grave's disease (hyperthyroidism) - example of
2
altering thyroid function, but does not destroy
thyroid tissue
Incompatible blood type- example of
cell/tissue damage that occurs; severe
transfusion reaction occurs and the transfused
erythrocytes are destroyed by agglutination
or complement-mediated lysis.
, Type 1 Hypersensitivity
Organ Specific
Antibody binds to the antigen on the cell
surface
Type 1
Hypersensitivity VS.
Type 2 Hypersensitivity
Type 2
Not Organ Specific
Hypersensitivity
Antibody binds to the soluble antigen outside
the cell surface that was released into the
blood or body fluids, and the complex is then
deposited in the tissues
