PHA 317 Comprehensive Review
For Final Exam Questions and
Answers 100% Pass
Cup and Bob type of viscometer may be used for gels and pastes - CORRECT
ANSWER-True
For nitroglycerine (NTG), it is important to counsel patient not to remove tablets
from packaging until they actually use the tablets. This is due to what characteristic
of NTG? - CORRECT ANSWER-NTG is susceptible to loss by sublimation at
room temperature
The most stable polymorph is always used for better clinical outcomes -
CORRECT ANSWER-False
Which of the following does NOT increase aqueous solubility - CORRECT
ANSWER-Increasing the length of a straight chain organic compounds
Increasing which of the following will increase permeability of a molecule across a
biological membrane - CORRECT ANSWER-Diffusivity of the molecule
,100mL of water was added to a 200mL solution. When the total volume was
measured, it was found only 298mL even if there is no loss of material during
mixing. Is this a real solution - CORRECT ANSWER-Yes
1g of a drug s soluble in 10.50 L of water. Which one of the following correctly
define its solubility as per USP definition - CORRECT ANSWER-Practically
insoluble
A matter that exhibits plastic flow, below its yield value would behave as -
CORRECT ANSWER-Elastic flow
The arrhenius equation of rheology expresses the relationship between -
CORRECT ANSWER-Viscosity and temperature
Ostwald viscometer is used for - CORRECT ANSWER-liquids that flow relatively
easily
Pseudoplatic flow has a yield value - CORRECT ANSWER-False
The key factor in the viscoelasticity of blood are - CORRECT ANSWER-both
aggregation and deformability
1 centipoise is equal to - CORRECT ANSWER-0.01 poise
If the shearing stress is directly proportional to the rate of shear the liquid exhibits
a - CORRECT ANSWER-Newtonian flow
,Which one of the following facts are correct with respect to thixotropy -
CORRECT ANSWER-Exhibited by shear thinning systems, such as pseudoplastic
and plastic liquids
Can be defined as an isothermal and comparatively slow recovery, on standing of a
material, of a consistency lost through shearing
Behavior is useful for many pharmaceutical preps (suspensions)
Which one of the following is the most desirable flow characteristic for a dosage
form design - CORRECT ANSWER-Thixotropic flow
Under which situation will the viscosity of oil increase - CORRECT ANSWER-As
temperature decreases
Viscosity of an unknown liquid is 0.580 cp at 25 degrees celsius and the density is
0.858/cm cubed. What is the kinematic viscosity of the unknown liquid -
CORRECT ANSWER-0.676 centistrokes
Plastic flow is associated with - CORRECT ANSWER-Suspensions
For Newtonian fluids, if the rate of shear is increased two times from its original
value while the viscosity remains constant. What change could you expect in
shearing stress of that liquid - CORRECT ANSWER-Double it's original value
Thixotropy is a special characteristic that is exhibited by shear thinning systems,
such as - CORRECT ANSWER-Plastic and Pseudoplastic
Polymers in a solution generally exhibit plastic flow - CORRECT ANSWER-False
, A solution isoosmotic with blood would be isotonic too - CORRECT ANSWER-
False
Molarity of a solution does not depend on temperature of the solution -
CORRECT ANSWER-False
What is the normality of the 100mL solution containing 585 mg of NaCl in water -
CORRECT ANSWER-0.1N
Indicate which of the following is correct about osmosis - CORRECT ANSWER-
Osmotic pressure is proportional to number of ions or molecules of solute
dissolved in solvent
Which one of the following statements is correct about diarrhea - CORRECT
ANSWER-There is a co-transport system unaffected by diarrhea causing
microorganism, which transports Na+ ions to blood only when glucose is also
present
Hydrogen peroxide is stored in dark container to prevent it from - CORRECT
ANSWER-photolysis
The rate of specific acid and base catalysis is affected by concentration of
undissociated buffer components in addition to hydronium and hydroxyl ion
concentration - CORRECT ANSWER-false
the release of a drug from matrix system occurs by - CORRECT ANSWER-
diffusion from the matrix system and erosion of the matrix system
For Final Exam Questions and
Answers 100% Pass
Cup and Bob type of viscometer may be used for gels and pastes - CORRECT
ANSWER-True
For nitroglycerine (NTG), it is important to counsel patient not to remove tablets
from packaging until they actually use the tablets. This is due to what characteristic
of NTG? - CORRECT ANSWER-NTG is susceptible to loss by sublimation at
room temperature
The most stable polymorph is always used for better clinical outcomes -
CORRECT ANSWER-False
Which of the following does NOT increase aqueous solubility - CORRECT
ANSWER-Increasing the length of a straight chain organic compounds
Increasing which of the following will increase permeability of a molecule across a
biological membrane - CORRECT ANSWER-Diffusivity of the molecule
,100mL of water was added to a 200mL solution. When the total volume was
measured, it was found only 298mL even if there is no loss of material during
mixing. Is this a real solution - CORRECT ANSWER-Yes
1g of a drug s soluble in 10.50 L of water. Which one of the following correctly
define its solubility as per USP definition - CORRECT ANSWER-Practically
insoluble
A matter that exhibits plastic flow, below its yield value would behave as -
CORRECT ANSWER-Elastic flow
The arrhenius equation of rheology expresses the relationship between -
CORRECT ANSWER-Viscosity and temperature
Ostwald viscometer is used for - CORRECT ANSWER-liquids that flow relatively
easily
Pseudoplatic flow has a yield value - CORRECT ANSWER-False
The key factor in the viscoelasticity of blood are - CORRECT ANSWER-both
aggregation and deformability
1 centipoise is equal to - CORRECT ANSWER-0.01 poise
If the shearing stress is directly proportional to the rate of shear the liquid exhibits
a - CORRECT ANSWER-Newtonian flow
,Which one of the following facts are correct with respect to thixotropy -
CORRECT ANSWER-Exhibited by shear thinning systems, such as pseudoplastic
and plastic liquids
Can be defined as an isothermal and comparatively slow recovery, on standing of a
material, of a consistency lost through shearing
Behavior is useful for many pharmaceutical preps (suspensions)
Which one of the following is the most desirable flow characteristic for a dosage
form design - CORRECT ANSWER-Thixotropic flow
Under which situation will the viscosity of oil increase - CORRECT ANSWER-As
temperature decreases
Viscosity of an unknown liquid is 0.580 cp at 25 degrees celsius and the density is
0.858/cm cubed. What is the kinematic viscosity of the unknown liquid -
CORRECT ANSWER-0.676 centistrokes
Plastic flow is associated with - CORRECT ANSWER-Suspensions
For Newtonian fluids, if the rate of shear is increased two times from its original
value while the viscosity remains constant. What change could you expect in
shearing stress of that liquid - CORRECT ANSWER-Double it's original value
Thixotropy is a special characteristic that is exhibited by shear thinning systems,
such as - CORRECT ANSWER-Plastic and Pseudoplastic
Polymers in a solution generally exhibit plastic flow - CORRECT ANSWER-False
, A solution isoosmotic with blood would be isotonic too - CORRECT ANSWER-
False
Molarity of a solution does not depend on temperature of the solution -
CORRECT ANSWER-False
What is the normality of the 100mL solution containing 585 mg of NaCl in water -
CORRECT ANSWER-0.1N
Indicate which of the following is correct about osmosis - CORRECT ANSWER-
Osmotic pressure is proportional to number of ions or molecules of solute
dissolved in solvent
Which one of the following statements is correct about diarrhea - CORRECT
ANSWER-There is a co-transport system unaffected by diarrhea causing
microorganism, which transports Na+ ions to blood only when glucose is also
present
Hydrogen peroxide is stored in dark container to prevent it from - CORRECT
ANSWER-photolysis
The rate of specific acid and base catalysis is affected by concentration of
undissociated buffer components in addition to hydronium and hydroxyl ion
concentration - CORRECT ANSWER-false
the release of a drug from matrix system occurs by - CORRECT ANSWER-
diffusion from the matrix system and erosion of the matrix system
