Blood Bank ASCP EXAM questions with |\ |\ |\ |\ |\ |\
answers
What type of serological testing does the blood
|\ |\ |\ |\ |\ |\ |\
bank technologist perform when determining the
|\ |\ |\ |\ |\
blood group of a patient? - CORRECT ANSWERS ✔✔phenotyping
|\ |\ |\ |\ |\ |\ |\ |\
If anti-K reacts 3+ with a donor cell with a
|\ |\ |\ |\ |\ |\ |\ |\ |\
genotype KK and 2+ with a Kk cell, the antibody |\ |\ |\ |\ |\ |\ |\ |\ |\
is demonstrating: - CORRECT ANSWERS ✔✔Dosage
|\ |\ |\ |\ |\
Carla expresses the blood group antigens Fya, Fyb, and Xga.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
James shows expressions of none of these antigens. What
|\ |\ |\ |\ |\ |\ |\ |\ |\
factor(s) may account for the absence of these antigens in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
James? - CORRECT ANSWERS ✔✔Gender and Race. The
|\ |\ |\ |\ |\ |\ |\ |\
frequency of Duffy antigens Fya and Fyb varies |\ |\ |\ |\ |\ |\ |\
with race. The Fy(a−b−) phenotype occurs in almost
|\ |\ |\ |\ |\ |\ |\
70% of African Americans and is very rare in whites.
|\ |\ |\ |\ |\ |\ |\ |\ |\
The Xga antigen is X-linked and, therefore, expressed more
|\ |\ |\ |\ |\ |\ |\ |\ |\
frequently in women (who may inherit the antigen from either
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
parent) than in men. |\ |\ |\
Which of the following statements is true?
|\ |\ |\ |\ |\ |\
A. An individual with the BO genotype is
|\ |\ |\ |\ |\ |\ |\
homozygous for B antigen |\ |\ |\
,B. An individual with the BB genotype is
|\ |\ |\ |\ |\ |\ |\
homozygous for B antigen |\ |\ |\
C. An individual with the OO genotype is
|\ |\ |\ |\ |\ |\ |\
heterozygous for O antigen |\ |\ |\
D. An individual with the AB phenotype is
|\ |\ |\ |\ |\ |\ |\
homozygous for A and B antigens - CORRECT ANSWERS ✔✔B. An |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
individual with the BB genotype is |\ |\ |\ |\ |\
homozygous for B antigen |\ |\ |\
Which genotype is heterozygous for C?
|\ |\ |\ |\ |\
A. DCe/dce
|\
B. DCE/DCE
|\
C. Dce/dce
|\
D. DCE/dCe - CORRECT ANSWERS ✔✔A. DCe/dce
|\ |\ |\ |\ |\ |\
Which genotype(s) will give rise to the Bombay phenotype? -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔The Bombay phenotype will be expressed
|\ |\ |\ |\ |\ |\ |\
only when no H substance is present. The Oh type is expressed
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
by the genotype hh. Bombays produce naturally occurring anti-H,
|\ |\ |\ |\ |\ |\ |\ |\
and their serum agglutinates group
|\ |\ |\ |\ |\
O red cells in addition to red cells from groups A, B, and AB
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
persons.
Meiosis in cell division is limited to the ova and sperm producing
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
four gametes containing what complement of DNA? - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔1N. Meiosis involves two nuclear divisions in
|\ |\ |\ |\ |\ |\ |\ |\
,succession resulting in four gametocytes each containing half the |\ |\ |\ |\ |\ |\ |\ |\
number of chromosomes found in somatic cells or 1N.
|\ |\ |\ |\ |\ |\ |\ |\ |\
A cell that is not actively dividing is said to be in: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔Interphase, The cell is engaged in metabolic |\ |\ |\ |\ |\ |\ |\ |\
activity. Chromosomes are not clearly discerned; however,
|\ |\ |\ |\ |\ |\ |\
nucleoli may be |\ |\
visible
Which of the following describes the expression of most blood
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
group antigens? - CORRECT ANSWERS ✔✔Codominant
|\ |\ |\ |\ |\
What blood type is not possible for an offspring of an AO and BO
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
mating? - CORRECT ANSWERS ✔✔All are possible |\ |\ |\ |\ |\ |\
The alleged father of a child in a disputed case of paternity is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
blood group AB. The mother is group O and the child is group O.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
What type of exclusion is this? - CORRECT ANSWERS ✔✔-
|\ |\ |\ |\ |\ |\ |\ |\ |\
Indirect/secondary/second order |\
An indirect/secondary/second order exclusion occurs when a
|\ |\ |\ |\ |\ |\ |\
genetic marker is absent in the child but should have been
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
transmitted by the alleged father. In this case, either A or B |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
should be present in the child. |\ |\ |\ |\ |\
If the frequency of gene Y is 0.4 and the frequency of gene Z is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
0.5, one would expect that they should occur together 0.2 (20%)
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of the time. In actuality,
|\ |\ |\ |\
they are found together 32% of the time. This is an example of: -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔Linkage disequilibrium. |\ |\ |\
, Linkage disequilibrium is a phenomenon in which alleles situated
|\ |\ |\ |\ |\ |\ |\ |\ |\
in close proximity on a chromosome associate with one another
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
more than would be expected from individual allelic frequencies.
|\ |\ |\ |\ |\ |\ |\ |\
In this type of inheritance, the father carries the trait on his X
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chromosome. He has no sons with the trait because he passed |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
his Y chromosome to his sons; however, all his daughters will
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
express the trait. - CORRECT ANSWERS ✔✔Autosomal Dominant
|\ |\ |\ |\ |\ |\ |\
In the Hardy-Weinberg formula, p2 represents: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔In the Hardy-Weinberg formula p2 + 2pq + q2, p2 |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
and q2 represent homozygous expressions and 2pq represents
|\ |\ |\ |\ |\ |\ |\ |\
heterozygous expression. This formula is |\ |\ |\ |\
used in population genetics to determine the frequency of
|\ |\ |\ |\ |\ |\ |\ |\ |\
different alleles. |\
What is the Hardy-Weinberg formula? - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔p2 + 2pq + q2 = 1 |\ |\ |\ |\ |\ |\
Why do IgM antibodies, such as those formed against the ABO
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
antigens, have the ability to directly agglutinate red blood cells
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
(RBCs) and cause visible agglutination? - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔IgM antibodies are larger molecules and have the ability to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
bind more antigen |\ |\
Which of the following enhancement mediums decreases the zeta
|\ |\ |\ |\ |\ |\ |\ |\
potential, allowing antibody and antigen to come closer
|\ |\ |\ |\ |\ |\ |\ |\ |\
together? - CORRECT ANSWERS ✔✔LISS. |\ |\ |\ |\
answers
What type of serological testing does the blood
|\ |\ |\ |\ |\ |\ |\
bank technologist perform when determining the
|\ |\ |\ |\ |\
blood group of a patient? - CORRECT ANSWERS ✔✔phenotyping
|\ |\ |\ |\ |\ |\ |\ |\
If anti-K reacts 3+ with a donor cell with a
|\ |\ |\ |\ |\ |\ |\ |\ |\
genotype KK and 2+ with a Kk cell, the antibody |\ |\ |\ |\ |\ |\ |\ |\ |\
is demonstrating: - CORRECT ANSWERS ✔✔Dosage
|\ |\ |\ |\ |\
Carla expresses the blood group antigens Fya, Fyb, and Xga.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
James shows expressions of none of these antigens. What
|\ |\ |\ |\ |\ |\ |\ |\ |\
factor(s) may account for the absence of these antigens in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
James? - CORRECT ANSWERS ✔✔Gender and Race. The
|\ |\ |\ |\ |\ |\ |\ |\
frequency of Duffy antigens Fya and Fyb varies |\ |\ |\ |\ |\ |\ |\
with race. The Fy(a−b−) phenotype occurs in almost
|\ |\ |\ |\ |\ |\ |\
70% of African Americans and is very rare in whites.
|\ |\ |\ |\ |\ |\ |\ |\ |\
The Xga antigen is X-linked and, therefore, expressed more
|\ |\ |\ |\ |\ |\ |\ |\ |\
frequently in women (who may inherit the antigen from either
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
parent) than in men. |\ |\ |\
Which of the following statements is true?
|\ |\ |\ |\ |\ |\
A. An individual with the BO genotype is
|\ |\ |\ |\ |\ |\ |\
homozygous for B antigen |\ |\ |\
,B. An individual with the BB genotype is
|\ |\ |\ |\ |\ |\ |\
homozygous for B antigen |\ |\ |\
C. An individual with the OO genotype is
|\ |\ |\ |\ |\ |\ |\
heterozygous for O antigen |\ |\ |\
D. An individual with the AB phenotype is
|\ |\ |\ |\ |\ |\ |\
homozygous for A and B antigens - CORRECT ANSWERS ✔✔B. An |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
individual with the BB genotype is |\ |\ |\ |\ |\
homozygous for B antigen |\ |\ |\
Which genotype is heterozygous for C?
|\ |\ |\ |\ |\
A. DCe/dce
|\
B. DCE/DCE
|\
C. Dce/dce
|\
D. DCE/dCe - CORRECT ANSWERS ✔✔A. DCe/dce
|\ |\ |\ |\ |\ |\
Which genotype(s) will give rise to the Bombay phenotype? -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔The Bombay phenotype will be expressed
|\ |\ |\ |\ |\ |\ |\
only when no H substance is present. The Oh type is expressed
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
by the genotype hh. Bombays produce naturally occurring anti-H,
|\ |\ |\ |\ |\ |\ |\ |\
and their serum agglutinates group
|\ |\ |\ |\ |\
O red cells in addition to red cells from groups A, B, and AB
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
persons.
Meiosis in cell division is limited to the ova and sperm producing
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
four gametes containing what complement of DNA? - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔1N. Meiosis involves two nuclear divisions in
|\ |\ |\ |\ |\ |\ |\ |\
,succession resulting in four gametocytes each containing half the |\ |\ |\ |\ |\ |\ |\ |\
number of chromosomes found in somatic cells or 1N.
|\ |\ |\ |\ |\ |\ |\ |\ |\
A cell that is not actively dividing is said to be in: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔Interphase, The cell is engaged in metabolic |\ |\ |\ |\ |\ |\ |\ |\
activity. Chromosomes are not clearly discerned; however,
|\ |\ |\ |\ |\ |\ |\
nucleoli may be |\ |\
visible
Which of the following describes the expression of most blood
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
group antigens? - CORRECT ANSWERS ✔✔Codominant
|\ |\ |\ |\ |\
What blood type is not possible for an offspring of an AO and BO
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
mating? - CORRECT ANSWERS ✔✔All are possible |\ |\ |\ |\ |\ |\
The alleged father of a child in a disputed case of paternity is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
blood group AB. The mother is group O and the child is group O.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
What type of exclusion is this? - CORRECT ANSWERS ✔✔-
|\ |\ |\ |\ |\ |\ |\ |\ |\
Indirect/secondary/second order |\
An indirect/secondary/second order exclusion occurs when a
|\ |\ |\ |\ |\ |\ |\
genetic marker is absent in the child but should have been
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
transmitted by the alleged father. In this case, either A or B |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
should be present in the child. |\ |\ |\ |\ |\
If the frequency of gene Y is 0.4 and the frequency of gene Z is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
0.5, one would expect that they should occur together 0.2 (20%)
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of the time. In actuality,
|\ |\ |\ |\
they are found together 32% of the time. This is an example of: -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔Linkage disequilibrium. |\ |\ |\
, Linkage disequilibrium is a phenomenon in which alleles situated
|\ |\ |\ |\ |\ |\ |\ |\ |\
in close proximity on a chromosome associate with one another
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
more than would be expected from individual allelic frequencies.
|\ |\ |\ |\ |\ |\ |\ |\
In this type of inheritance, the father carries the trait on his X
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chromosome. He has no sons with the trait because he passed |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
his Y chromosome to his sons; however, all his daughters will
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
express the trait. - CORRECT ANSWERS ✔✔Autosomal Dominant
|\ |\ |\ |\ |\ |\ |\
In the Hardy-Weinberg formula, p2 represents: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔In the Hardy-Weinberg formula p2 + 2pq + q2, p2 |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
and q2 represent homozygous expressions and 2pq represents
|\ |\ |\ |\ |\ |\ |\ |\
heterozygous expression. This formula is |\ |\ |\ |\
used in population genetics to determine the frequency of
|\ |\ |\ |\ |\ |\ |\ |\ |\
different alleles. |\
What is the Hardy-Weinberg formula? - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔p2 + 2pq + q2 = 1 |\ |\ |\ |\ |\ |\
Why do IgM antibodies, such as those formed against the ABO
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
antigens, have the ability to directly agglutinate red blood cells
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
(RBCs) and cause visible agglutination? - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔IgM antibodies are larger molecules and have the ability to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
bind more antigen |\ |\
Which of the following enhancement mediums decreases the zeta
|\ |\ |\ |\ |\ |\ |\ |\
potential, allowing antibody and antigen to come closer
|\ |\ |\ |\ |\ |\ |\ |\ |\
together? - CORRECT ANSWERS ✔✔LISS. |\ |\ |\ |\
