COMSAE 107 EXAM STUDY GUIDE
DMARD drug for UC/Crohns/RA - Answer -sulfasalazine
pulmonary effects of CF - Answer -chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - Answer -(spongy and ) trabecular bone
mass loss
imipramine - Answer -TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension-
block alpha1)
viscerosomatic - Answer -visceral disease --> somatic finding
loratidine vs ranitidine - Answer -loratidine: 2nd gen H1 blocker, doesnt cross BBB -->
less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
cells w RBCs inside - Answer -entaemoba histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - Answer -
tension
intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous
tortuous vessels - Answer -AVM arteriovenous malformation
cavernous hemangioma - Answer -benign tumor of liver, A/W VHL
anti-HepB surface antibody is only present in what pop - Answer -recovered or
immunized
not in chronic or
proctalgia fugax - Answer -levator ani syndrome
fasciculus is UMN or LMN lesion? - Answer -LMN
,ectopic gastric tissue - Answer -meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
antibodies in hashimotos attacks - Answer -thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
2 factors that influence starling curve - Answer -x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia - Answer -TCA, SNRIs anticonvulsants
what blocks NE reuptake? - Answer -TCA or SNRIs
possible complication of pagets bone disease - Answer -osteocarcoma
what does Hct tell you? - Answer -ratio of volume of RBCs compared to total blood
volume
probenecid - Answer -inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
2 causes of SCID - Answer -ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
lithiums effects on urination - Answer -inhibits vasopression/ADH --> increased urinary
frequency
infertility drug that can result in multiple fetuses - Answer -clomiphene (clones- multiple
babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
AFP levels in down syndrome - Answer -low
,GI malformation A/W down syndrome - Answer -Hirschprungs- congenital aganglionic
megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - Answer -thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea - Answer -azoles
beta blockers for asthma - Answer -none- even beta 1s can be nonselective at higher
doses
what kind of teratogenic effects are seen w ACE/ARBs - Answer -fetal renal agenesis
stones bones groans moans psych overtones - Answer -high Ca or PTH
PTH is made by what cells? - Answer -chief cells of parathyroid gland
PTH inhibits reabsorption of phosphate where? increases calcium resorption where? -
Answer -PO4- proximal tubule
ca- DCT
anterior innominate rotation means tight hip flexors or extensors? - Answer -extensor-
hamstrings
thoracic CS - Answer -E SaRa
most common cause of cellultis - Answer -staph aureus, strep pyogenes
FPR- direct or indirect? active or passive? - Answer -indirect- place them in position of
diagnosis
passive
cant treat kid w tetracycline so what do you give? - Answer -amoxicillin
which Heps are there currently vaccines for? - Answer -A and B (and so by virtue, also
D)
why does Hep D need Hep B? - Answer -Hep D utilizes the HBV surface antigen as its
envelope?
most common hepatitis A/W IVDA in the US - Answer -hep c
, roseola - Answer -4 day high fever
then rash on the trunk (spares face)
affects babies up to 2 years
HHV6- affects CD4 helper cells and kills them off
erythema infectiosum - Answer -slapped cheek
parvovirus B19
nonspecific fever/prodrome then slapp cheek rash 5 days later, then rash appears on
arms and spreads to trunk/legs
rash can worsen w fever and sun exposure
TORCH infxn so baby in womb that is exposed can lead to hydrops fetalis
most common STD - Answer -chlamydia
sxs similar to STI plus discharge
will have high neutrophil count
dimorphic- butterflies - Answer -candida, histo, cocci, paracocci, blasto, sporothrix,
butterflies huge pair of cocc catching stamp
hip restricted in internal rotation
dx? - Answer -innom outflare
immune complex in glomerular mesangium 2 days after URI
berger or PSGN? - Answer -berger
PSGN is 2 wks post URI
kidney ureter viscerosomatic innervation - Answer -T10-11
college student w nonspecific symptoms
nonproductive cough, sore throat
CXR- diffuse infiltrates - Answer -myco PNA
DMARD drug for UC/Crohns/RA - Answer -sulfasalazine
pulmonary effects of CF - Answer -chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - Answer -(spongy and ) trabecular bone
mass loss
imipramine - Answer -TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension-
block alpha1)
viscerosomatic - Answer -visceral disease --> somatic finding
loratidine vs ranitidine - Answer -loratidine: 2nd gen H1 blocker, doesnt cross BBB -->
less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
cells w RBCs inside - Answer -entaemoba histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - Answer -
tension
intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous
tortuous vessels - Answer -AVM arteriovenous malformation
cavernous hemangioma - Answer -benign tumor of liver, A/W VHL
anti-HepB surface antibody is only present in what pop - Answer -recovered or
immunized
not in chronic or
proctalgia fugax - Answer -levator ani syndrome
fasciculus is UMN or LMN lesion? - Answer -LMN
,ectopic gastric tissue - Answer -meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
antibodies in hashimotos attacks - Answer -thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
2 factors that influence starling curve - Answer -x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia - Answer -TCA, SNRIs anticonvulsants
what blocks NE reuptake? - Answer -TCA or SNRIs
possible complication of pagets bone disease - Answer -osteocarcoma
what does Hct tell you? - Answer -ratio of volume of RBCs compared to total blood
volume
probenecid - Answer -inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
2 causes of SCID - Answer -ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
lithiums effects on urination - Answer -inhibits vasopression/ADH --> increased urinary
frequency
infertility drug that can result in multiple fetuses - Answer -clomiphene (clones- multiple
babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
AFP levels in down syndrome - Answer -low
,GI malformation A/W down syndrome - Answer -Hirschprungs- congenital aganglionic
megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - Answer -thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea - Answer -azoles
beta blockers for asthma - Answer -none- even beta 1s can be nonselective at higher
doses
what kind of teratogenic effects are seen w ACE/ARBs - Answer -fetal renal agenesis
stones bones groans moans psych overtones - Answer -high Ca or PTH
PTH is made by what cells? - Answer -chief cells of parathyroid gland
PTH inhibits reabsorption of phosphate where? increases calcium resorption where? -
Answer -PO4- proximal tubule
ca- DCT
anterior innominate rotation means tight hip flexors or extensors? - Answer -extensor-
hamstrings
thoracic CS - Answer -E SaRa
most common cause of cellultis - Answer -staph aureus, strep pyogenes
FPR- direct or indirect? active or passive? - Answer -indirect- place them in position of
diagnosis
passive
cant treat kid w tetracycline so what do you give? - Answer -amoxicillin
which Heps are there currently vaccines for? - Answer -A and B (and so by virtue, also
D)
why does Hep D need Hep B? - Answer -Hep D utilizes the HBV surface antigen as its
envelope?
most common hepatitis A/W IVDA in the US - Answer -hep c
, roseola - Answer -4 day high fever
then rash on the trunk (spares face)
affects babies up to 2 years
HHV6- affects CD4 helper cells and kills them off
erythema infectiosum - Answer -slapped cheek
parvovirus B19
nonspecific fever/prodrome then slapp cheek rash 5 days later, then rash appears on
arms and spreads to trunk/legs
rash can worsen w fever and sun exposure
TORCH infxn so baby in womb that is exposed can lead to hydrops fetalis
most common STD - Answer -chlamydia
sxs similar to STI plus discharge
will have high neutrophil count
dimorphic- butterflies - Answer -candida, histo, cocci, paracocci, blasto, sporothrix,
butterflies huge pair of cocc catching stamp
hip restricted in internal rotation
dx? - Answer -innom outflare
immune complex in glomerular mesangium 2 days after URI
berger or PSGN? - Answer -berger
PSGN is 2 wks post URI
kidney ureter viscerosomatic innervation - Answer -T10-11
college student w nonspecific symptoms
nonproductive cough, sore throat
CXR- diffuse infiltrates - Answer -myco PNA
