Reliable Solutions
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Gold standard Xa: 0.2-04 units/mL for VV or 0.3-0.5 units/mL for VA
ACT Goal 180-220 seconds
APTT Goal 40-60 seconds for VV; 50-75 seconds for VA
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1 Who is the 'father' of ECMO? 2 CaO2 Formula
What are the 4 components of oxygen
3 Anticoagulation Therapeutic Goals: 4
delivery?
Don't know?
Terms in this set (83)
Who is the 'father' of Robert Bartlett
ECMO?
First successful neonate Esperanza in 1975
ECMO run?
, How does gas exchange Diffusion (area of higher concentration to an area of
occur at the alveoli and lower concentration)
pulmonary capillaries?
How fast does gas 3/4 of a second
exchange occur at the
alveoli and pulmonary
capillaries?
1. Cardiac Output
What are the 4
2. Hemoglobin Concentration
components of oxygen
3. Hemoglobin Saturation
delivery?
4. Dissolved Oxygen
Ideal DO2/VO2 Ratio? 4:1
What is the metabolic rate The heart consumes 70-75% of the oxygen it is supplied
of the heart?
1. Cell Metabolism
What determines VO2? 2. Mass and Activity
3. Thyroid, Hypothalamus, and Catecholamines
- Measures global O2 consumption and utilization
- Normal is 65-75%
Facts about SVO2: - SvO2 = DO2-VO2
- <50% will lead to anaerobic metabolism (lactic acid
production)
- The amount of O2 added to the inlet blood (Starting
Oxygenation is controlled CaO2)
by: (gas exchange with - Blood Flow
membrane lung) - Surface Area
- Rated flow (tested in lab)
CO2 is controlled by: (gas - Sweep gas flow
exchange with membrane - Percent of O2 in sweep gas
lung) - Surface area
- 98.5% of oxygen is bound to hemoglobin; 1.5% is
dissolved in the plasma
Oxygen/CO2 Transport:
- HCO3 60%, carbaminohemoglobin 30%, dissolved in
plasma 10%
CaO2 = [(Hgb x 1.34) x SaO2] + [PaO2 x 0.003]
CaO2 Formula Use decimal for SaO2 only
Normal is 20mL/dL (>15 mL/dL is GREAT for ICU patients)