,TABLE OF CONTENTSnm nm
UNIT I Introduction to Pharmacology
nm nm nm nm
1 Basic Principles of Pharmacology
nm nm nm
2 Drug Actions Across the Life Span
nm nm nm nm nm
3 The Nursing Process and Pharmacology
nm nm nm nm
4 Patient Education to Promote Health
nm nm nm nm
UNIT II Medication Administration
nm nm nm
5 Principles of Medication Administration and Medication Safety
nm nm nm nm nm nm
6 Percutaneous Administration nm
7 Enteral Administration
nm
8 Parenteral Administration: Safe Preparation
nm nm nm
9 Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
nm nm nm nm nm
10 Parenteral Administration: Intravenous
nm nm
UNIT III Drugs Affecting Neurologic Disorders
nm nm nm nm nm
11 Drugs Affecting the Central and Peripheral Nervous System
nm nm nm nm nm nm nm
12 Drugs Used to Treat Neurodegenerative Disorders
nm nm nm nm nm
13 Drugs Used to Treat Seizure Disorders
nm nm nm nm nm
14 Drugs Used to Treat Headaches
nm nm nm nm
15 Drugs Used to Treat Pain: Focus on Opioids
nm nm nm nm nm nm nm
UNIT IV Drugs Affecting Psychiatric Disorders
nm nm nm nm nm
16 Drugs Used to Treat Attention Deficit Hyperactivity Disorder
nm nm nm nm nm nm nm
17 Drugs Used to Treat Substance Use Disorders
nm nm nm nm nm nm
18 Drugs Used to Treat Schizophrenia
nm nm nm nm
19 Drugs Used to Treat Depressive and Bipolar Disorders
nm nm nm nm nm nm nm
20 Drugs Used to Treat Anxiety Disorders
nm nm nm nm nm
21 Drugs Used to Treat Sleep Disorders
nm nm nm nm nm
UNIT V Drugs Affecting Cardiovascular Disorders
nm nm nm nm nm
22 Drugs Used to Treat Dyslipidemias
nm nm nm nm
23 Drugs Used to Treat Hypertension
nm nm nm nm
24 Drugs Used to Treat Arrhythmias
nm nm nm nm
25 Drugs Used to Treat Angina Pectoris
nm nm nm nm nm
26 Drugs Used to Treat Peripheral Vascular Disease
nm nm nm nm nm nm
27 Drugs Used to Treat Thromboembolic Disorders
nm nm nm nm nm
28 Drugs Used to Treat Heart Failure
nm nm nm nm nm
UNIT VI Drugs Affecting the Respiratory System
nm nm nm nm nm nm
29 Drugs Used to Treat Upper Respiratory Disease
nm nm nm nm nm nm
30 Drugs Used to Treat Lower Respiratory Disease
nm nm nm nm nm nm
UNIT VII Drugs Affecting the Digestive System
nm nm nm nm nm nm
31 Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
nm nm nm nm nm nm nm nm nm
32 Drugs Used to Treat Nausea and Vomiting
nm nm nm nm nm nm
33 Drugs Used to Treat Constipation and Diarrhea
nm nm nm nm nm nm
UNIT VIII Drugs Affecting the Endocrine System
nm nm nm nm nm nm
34 Drugs Used to Treat Diabetes Mellitus
nm nm nm nm nm
35 Drugs Used to Treat Thyroid Disease
nm nm nm nm nm
UNIT IX Drugs Affecting the Reproductive System
nm nm nm nm nm nm
36 Drugs Used in Obstetrics
nm nm nm
37 Drugs Used in Men’s and Women’s Health
nm nm nm nm nm nm
UNIT X Drugs Affecting Other Body Systems
nm nm nm nm nm nm
38 Drugs Used to Treat Urinary System Disorders
nm nm nm nm nm nm
39 Drugs Used to Treat Glaucoma and Other Eye Disorders
nm nm nm nm nm nm nm nm
40 Drugs Used to Treat Cancer
nm nm nm nm
41 Drugs Used to Treat Musculoskeletal Disorders
nm nm nm nm nm
42 Drugs Used to Treat Immune and Inflammatory Disorders
nm nm nm nm nm nm nm
,UNIT XI Drugs Used to Treat Infections
nm nm nm nm nm nm
43 Drugs Used to Treat Bacterial Infections
nm nm nm nm nm
44 Drugs Used to Treat Viral Infections
nm nm nm nm nm
45 Drugs Used to Treat Fungal Infections
nm nm nm nm nm
Chapter 01: Basic Principles of Pharmacology Willihnga nz: Clayton’s Basic Pharm
nm nm nm nm nm nm nm nm nm nm
acology for Nurses, 20th Edition
n m nm nm nm
MULTIPLE CHOICE nm
1. Which priority action should be implemented when hives are assessed on a patient started
nm nm nm nm nm nm nm nm nm nm nm nm nm n
o n a new medication?
m nm nm nm nm
a. Notify physician of allergic reaction. nm n m nm nm
b. Notify physician of idiosyncratic reaction. nm nm nm nm
c. Notify physician of potential teratogenicity. nm nm nm nm
d. Notify the physician of potential tolerance. nm nm nm nm nm
ANS: A n m
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urtica
nm nm nm nm nm nm nm nm nm nm nm nm
ri a , w h i c h are easily identified. An idiosyncratic reaction occurs when something unusua
nm l nm nm nm nm nm n m nm nm nm nm nm nm nm nm nm
l or abnormal happens when a drug is first administered. A teratogenic reaction refers to t
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
he oc currence of birth defects related to administration of the drug. Tolerance refers to th
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
e body‘s requirement for increasing dosages to achieve the same effects that a lower d
nm nm n m nm nm nm n m nm nm n m nm n m nm n m
ose once did. nm nm
DIF: Cognitive Level: Application nm nm REF: p. 17 nm OBJ: 4 n m
, NAT: NCLEX Client Needs Category: Physiological Integrity
n m nm nm nm nm nm
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
nm nm nm n m n m nm n m nm
2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes a ft
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
er administration, the nurse finds the patient agitated and stating that ―everyone is out to
nm nm nm n m nm nm nm nm nm nm nm nm nm nm nm
get me.‖ Which term is used for this unusual reaction?
nm nm nm nm nm n m nm nm nm
a. Desired action nm
b. Adverse effect nm
c. Idiosyncratic reaction nm
d. Allergic reaction nm
ANS: C n m
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is firs
nm nm nm nm nm nm nm nm nm nm nm nm
t administered. Patients typically exhibit an overresponsiveness to a medication relate
nm nm nm nm nm nm nm nm nm nm
d to diminished metabolism. These reactions are believed to be related to genetic en
nm n m nm nm nm nm nm nm nm nm nm nm nm
zy me deficiencies. Desired actions are expected responses to a medication. Adverse e
nm nm nm nm nm nm nm nm nm nm nm nm
ffect s are reactions that occur in another system of the body; they are usually predi
nm nm n m nm nm nm nm nm nm nm nm nm nm nm nm
ctable.
Allergic reactions appear after repeated medication dosages.
nm nm nm nm nm nm
DIF: Cognitive Level: Knowledge REF: p. 18 nm nm nm
OBJ: 4 NAT: NCLEX Client Needs Category: Physiological Int
nm nm n m nm nm nm nm nm
egrity
TOP: Nursing Process Step: Evaluation
n m nm nm nm
CON: Patient Education | Clinical Judgment | Caregiving | Safety | Sensory Perception
n m n m n m nm nm n m nm n m nm n m nm nm
3. Which is the best description of when drug interactions occur?
nm nm nm n m nm nm nm nm nm
a. On administration of toxic dosages of a drug
nm nm nm nm nm nm nm
b. On an increase in the pharmacodynamics of bound drugs
nm nm nm nm nm nm nm nm
c. On the alteration of the effect of one drug byanother drug
nm nm nm nm nm n m nm nm nm nm
d. On increase of drug excretion
nm nm nm nm
ANS: C n m
Drug interactions may be characterized byan increase or decrease in the effectiveness of
nm n m nm nm n m nm nm nm nm nm nm nm nm
o ne or both of the drugs. Toxicity of one drug may or may not affect the metabolism of
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
an other one. Drug interactions may result from either increased or decreased pharmacod
nm nm nm nm nm nm n m nm n m nm nm nm
yna mics. nm
Drug interactions mayresult from either increased or decreased excretion.
nm nm n m nm nm n m nm n m
DIF: Cognitive Level: Comprehension REF: p. 18 nm nm nm
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Int
nm nm n m nm nm nm nm nm
egrity
TOP: Nursing Process Step: Assessment nm nm nm n m CON: n m Safety | Patient Education | Clinical Judgment
nm nm n m nm nm nm
4. Which term describes when two drugs compete for the same receptor site, resultin
nm nm nm nm nm nm nm nm nm nm nm nm
g in increased activity of the first drug?
nm nm nm nm nm n m n m
a. Desired action nm
b. Synergistic effect nm
c. Carcinogenicity
d. Displacement
ANS: D n m
UNIT I Introduction to Pharmacology
nm nm nm nm
1 Basic Principles of Pharmacology
nm nm nm
2 Drug Actions Across the Life Span
nm nm nm nm nm
3 The Nursing Process and Pharmacology
nm nm nm nm
4 Patient Education to Promote Health
nm nm nm nm
UNIT II Medication Administration
nm nm nm
5 Principles of Medication Administration and Medication Safety
nm nm nm nm nm nm
6 Percutaneous Administration nm
7 Enteral Administration
nm
8 Parenteral Administration: Safe Preparation
nm nm nm
9 Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
nm nm nm nm nm
10 Parenteral Administration: Intravenous
nm nm
UNIT III Drugs Affecting Neurologic Disorders
nm nm nm nm nm
11 Drugs Affecting the Central and Peripheral Nervous System
nm nm nm nm nm nm nm
12 Drugs Used to Treat Neurodegenerative Disorders
nm nm nm nm nm
13 Drugs Used to Treat Seizure Disorders
nm nm nm nm nm
14 Drugs Used to Treat Headaches
nm nm nm nm
15 Drugs Used to Treat Pain: Focus on Opioids
nm nm nm nm nm nm nm
UNIT IV Drugs Affecting Psychiatric Disorders
nm nm nm nm nm
16 Drugs Used to Treat Attention Deficit Hyperactivity Disorder
nm nm nm nm nm nm nm
17 Drugs Used to Treat Substance Use Disorders
nm nm nm nm nm nm
18 Drugs Used to Treat Schizophrenia
nm nm nm nm
19 Drugs Used to Treat Depressive and Bipolar Disorders
nm nm nm nm nm nm nm
20 Drugs Used to Treat Anxiety Disorders
nm nm nm nm nm
21 Drugs Used to Treat Sleep Disorders
nm nm nm nm nm
UNIT V Drugs Affecting Cardiovascular Disorders
nm nm nm nm nm
22 Drugs Used to Treat Dyslipidemias
nm nm nm nm
23 Drugs Used to Treat Hypertension
nm nm nm nm
24 Drugs Used to Treat Arrhythmias
nm nm nm nm
25 Drugs Used to Treat Angina Pectoris
nm nm nm nm nm
26 Drugs Used to Treat Peripheral Vascular Disease
nm nm nm nm nm nm
27 Drugs Used to Treat Thromboembolic Disorders
nm nm nm nm nm
28 Drugs Used to Treat Heart Failure
nm nm nm nm nm
UNIT VI Drugs Affecting the Respiratory System
nm nm nm nm nm nm
29 Drugs Used to Treat Upper Respiratory Disease
nm nm nm nm nm nm
30 Drugs Used to Treat Lower Respiratory Disease
nm nm nm nm nm nm
UNIT VII Drugs Affecting the Digestive System
nm nm nm nm nm nm
31 Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
nm nm nm nm nm nm nm nm nm
32 Drugs Used to Treat Nausea and Vomiting
nm nm nm nm nm nm
33 Drugs Used to Treat Constipation and Diarrhea
nm nm nm nm nm nm
UNIT VIII Drugs Affecting the Endocrine System
nm nm nm nm nm nm
34 Drugs Used to Treat Diabetes Mellitus
nm nm nm nm nm
35 Drugs Used to Treat Thyroid Disease
nm nm nm nm nm
UNIT IX Drugs Affecting the Reproductive System
nm nm nm nm nm nm
36 Drugs Used in Obstetrics
nm nm nm
37 Drugs Used in Men’s and Women’s Health
nm nm nm nm nm nm
UNIT X Drugs Affecting Other Body Systems
nm nm nm nm nm nm
38 Drugs Used to Treat Urinary System Disorders
nm nm nm nm nm nm
39 Drugs Used to Treat Glaucoma and Other Eye Disorders
nm nm nm nm nm nm nm nm
40 Drugs Used to Treat Cancer
nm nm nm nm
41 Drugs Used to Treat Musculoskeletal Disorders
nm nm nm nm nm
42 Drugs Used to Treat Immune and Inflammatory Disorders
nm nm nm nm nm nm nm
,UNIT XI Drugs Used to Treat Infections
nm nm nm nm nm nm
43 Drugs Used to Treat Bacterial Infections
nm nm nm nm nm
44 Drugs Used to Treat Viral Infections
nm nm nm nm nm
45 Drugs Used to Treat Fungal Infections
nm nm nm nm nm
Chapter 01: Basic Principles of Pharmacology Willihnga nz: Clayton’s Basic Pharm
nm nm nm nm nm nm nm nm nm nm
acology for Nurses, 20th Edition
n m nm nm nm
MULTIPLE CHOICE nm
1. Which priority action should be implemented when hives are assessed on a patient started
nm nm nm nm nm nm nm nm nm nm nm nm nm n
o n a new medication?
m nm nm nm nm
a. Notify physician of allergic reaction. nm n m nm nm
b. Notify physician of idiosyncratic reaction. nm nm nm nm
c. Notify physician of potential teratogenicity. nm nm nm nm
d. Notify the physician of potential tolerance. nm nm nm nm nm
ANS: A n m
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urtica
nm nm nm nm nm nm nm nm nm nm nm nm
ri a , w h i c h are easily identified. An idiosyncratic reaction occurs when something unusua
nm l nm nm nm nm nm n m nm nm nm nm nm nm nm nm nm
l or abnormal happens when a drug is first administered. A teratogenic reaction refers to t
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
he oc currence of birth defects related to administration of the drug. Tolerance refers to th
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
e body‘s requirement for increasing dosages to achieve the same effects that a lower d
nm nm n m nm nm nm n m nm nm n m nm n m nm n m
ose once did. nm nm
DIF: Cognitive Level: Application nm nm REF: p. 17 nm OBJ: 4 n m
, NAT: NCLEX Client Needs Category: Physiological Integrity
n m nm nm nm nm nm
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
nm nm nm n m n m nm n m nm
2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes a ft
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
er administration, the nurse finds the patient agitated and stating that ―everyone is out to
nm nm nm n m nm nm nm nm nm nm nm nm nm nm nm
get me.‖ Which term is used for this unusual reaction?
nm nm nm nm nm n m nm nm nm
a. Desired action nm
b. Adverse effect nm
c. Idiosyncratic reaction nm
d. Allergic reaction nm
ANS: C n m
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is firs
nm nm nm nm nm nm nm nm nm nm nm nm
t administered. Patients typically exhibit an overresponsiveness to a medication relate
nm nm nm nm nm nm nm nm nm nm
d to diminished metabolism. These reactions are believed to be related to genetic en
nm n m nm nm nm nm nm nm nm nm nm nm nm
zy me deficiencies. Desired actions are expected responses to a medication. Adverse e
nm nm nm nm nm nm nm nm nm nm nm nm
ffect s are reactions that occur in another system of the body; they are usually predi
nm nm n m nm nm nm nm nm nm nm nm nm nm nm nm
ctable.
Allergic reactions appear after repeated medication dosages.
nm nm nm nm nm nm
DIF: Cognitive Level: Knowledge REF: p. 18 nm nm nm
OBJ: 4 NAT: NCLEX Client Needs Category: Physiological Int
nm nm n m nm nm nm nm nm
egrity
TOP: Nursing Process Step: Evaluation
n m nm nm nm
CON: Patient Education | Clinical Judgment | Caregiving | Safety | Sensory Perception
n m n m n m nm nm n m nm n m nm n m nm nm
3. Which is the best description of when drug interactions occur?
nm nm nm n m nm nm nm nm nm
a. On administration of toxic dosages of a drug
nm nm nm nm nm nm nm
b. On an increase in the pharmacodynamics of bound drugs
nm nm nm nm nm nm nm nm
c. On the alteration of the effect of one drug byanother drug
nm nm nm nm nm n m nm nm nm nm
d. On increase of drug excretion
nm nm nm nm
ANS: C n m
Drug interactions may be characterized byan increase or decrease in the effectiveness of
nm n m nm nm n m nm nm nm nm nm nm nm nm
o ne or both of the drugs. Toxicity of one drug may or may not affect the metabolism of
nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm nm
an other one. Drug interactions may result from either increased or decreased pharmacod
nm nm nm nm nm nm n m nm n m nm nm nm
yna mics. nm
Drug interactions mayresult from either increased or decreased excretion.
nm nm n m nm nm n m nm n m
DIF: Cognitive Level: Comprehension REF: p. 18 nm nm nm
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Int
nm nm n m nm nm nm nm nm
egrity
TOP: Nursing Process Step: Assessment nm nm nm n m CON: n m Safety | Patient Education | Clinical Judgment
nm nm n m nm nm nm
4. Which term describes when two drugs compete for the same receptor site, resultin
nm nm nm nm nm nm nm nm nm nm nm nm
g in increased activity of the first drug?
nm nm nm nm nm n m n m
a. Desired action nm
b. Synergistic effect nm
c. Carcinogenicity
d. Displacement
ANS: D n m