CSO Exam - CH 18 Breast Cancer Questions
with Correct Answers 2025/2026
Breast cancer is the leading cause of cancer death - CORRECT ANSWER -2nd
Majority of breast cancer is from cell lining and . - CORRECT
ANSWER -milk ducts
breast lobules
There is a lower risk of death when breast cancer pt do this. - CORRECT ANSWER -PA -- nurses
health study + collaborate women's longevity study
MET -- metabolic equivalent task -- 3 per week
High intake of what 2 things is beneficial? - CORRECT ANSWER -fruits + vegs
What percent of women will develop breast cancer if they have the BRAC1 or BRAC2 gene? -
CORRECT ANSWER -80%
What is the treatment if caught early stage? - CORRECT ANSWER -Lumpectomy -- breast
conserving- -- followed by XRT
ER + disease use hormone therapy = SERMS + AI's - CORRECT ANSWER -SERMs (selective
estrogen receptor modulators) - tamoxifen, raloxifene, fluvestrant) -- decrease growth of
estrogen-sensitive cells by binding to the estrogen receptor
AI's (aromatase inhibitors)- anastrozole, exemestane, letrozole -- block estrogen receptors
, high-risk post-meno women had 50% reduced risk of developing cancer when using this (breast
cancer prevention trial) - CORRECT ANSWER -tamoxifen
NCI study of Tamoxifen vs raloxifene found what - CORRECT ANSWER -
both effective in reducing the risk among high risk disease
what monoclonal antibody is used for breast cancers that overproduce HER2 -
CORRECT ANSWER -trastuzumab
AI's but not SERMS are associated with what SE? - CORRECT ANSWER -bone loss ---
> Ca + Vit D
how to ERD's work? (Estrogen-receptor down-regulators) - CORRECT ANSWER -
block effects of estrogen In breast tissue
how to LHRHs work? (Luteinizing hormone-relasing agents) - CORRECT ANSWER -
Lupron, Depot, Zoladex
shut down ovaries so they do not produce estrogen
incidence of mixed ER/PR cancers - CORRECT ANSWER -ER - PR - ===== 20%
ER + PR - ==== 10%
ER - PR + ===== 5%
HER 2 + breast cancer - CORRECT ANSWER -20% of cancers
fast growing + aggressive
Monoclonal antibody -- herceptin
Triple negative breast cancer - CORRECT ANSWER -15-20%
with Correct Answers 2025/2026
Breast cancer is the leading cause of cancer death - CORRECT ANSWER -2nd
Majority of breast cancer is from cell lining and . - CORRECT
ANSWER -milk ducts
breast lobules
There is a lower risk of death when breast cancer pt do this. - CORRECT ANSWER -PA -- nurses
health study + collaborate women's longevity study
MET -- metabolic equivalent task -- 3 per week
High intake of what 2 things is beneficial? - CORRECT ANSWER -fruits + vegs
What percent of women will develop breast cancer if they have the BRAC1 or BRAC2 gene? -
CORRECT ANSWER -80%
What is the treatment if caught early stage? - CORRECT ANSWER -Lumpectomy -- breast
conserving- -- followed by XRT
ER + disease use hormone therapy = SERMS + AI's - CORRECT ANSWER -SERMs (selective
estrogen receptor modulators) - tamoxifen, raloxifene, fluvestrant) -- decrease growth of
estrogen-sensitive cells by binding to the estrogen receptor
AI's (aromatase inhibitors)- anastrozole, exemestane, letrozole -- block estrogen receptors
, high-risk post-meno women had 50% reduced risk of developing cancer when using this (breast
cancer prevention trial) - CORRECT ANSWER -tamoxifen
NCI study of Tamoxifen vs raloxifene found what - CORRECT ANSWER -
both effective in reducing the risk among high risk disease
what monoclonal antibody is used for breast cancers that overproduce HER2 -
CORRECT ANSWER -trastuzumab
AI's but not SERMS are associated with what SE? - CORRECT ANSWER -bone loss ---
> Ca + Vit D
how to ERD's work? (Estrogen-receptor down-regulators) - CORRECT ANSWER -
block effects of estrogen In breast tissue
how to LHRHs work? (Luteinizing hormone-relasing agents) - CORRECT ANSWER -
Lupron, Depot, Zoladex
shut down ovaries so they do not produce estrogen
incidence of mixed ER/PR cancers - CORRECT ANSWER -ER - PR - ===== 20%
ER + PR - ==== 10%
ER - PR + ===== 5%
HER 2 + breast cancer - CORRECT ANSWER -20% of cancers
fast growing + aggressive
Monoclonal antibody -- herceptin
Triple negative breast cancer - CORRECT ANSWER -15-20%
