TESTBANK n
RUBIN'SPATHOLOGY:CLINICOPATHOLOGICFOUNDATIONSOF MEDICINE
n n n n n
7TH EDITION
n n
DAVIDS. STRAYER, EMANUELRUBIN
n n n n
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
n n n n n n n n n
Table of Contents:
n n
Chapter 1: Cell Adaptation, Injury and Death
n n n n n n
Chapter 2: Inflammation
n n
Chapter 3: Repair, Regeneration and Fibrosis
n n n n n
Chapter 4: Immunopathology
n n
Chapter 5: Neoplasia
n n
Chapter 6: Developmental and Genetic Diseases
n n n n n
Chapter 7: Hemodynamic Disorders
n n n
Chapter 8: Environmental and Nutritional Pathology
n n n n n
Chapter 9: Infectious and Parasitic Diseases
n n n n n
Section II: Pathogenesis of Systemic Conditions Expandable section
n n n n n n n
Chapter 10: Aging
n n
Chapter 11: Systemic Autoimmune Diseases
n n n n
Chapter 12: Sepsis
n n
Chapter 13: Obesity and Diabetes Mellitus
n n n n n
Chapter 14: The Pathology of Pregnancy
n n n n n
Chapter 15: The Amyloidoses
n n n
Section III: Diseases of Individual Organ SystemsExpandable section
n n n n n n n
Chapter 16: Blood Vessels
n n n
Chapter 17: The Heart
n n n
Chapter 18: The Respiratory System
n n n n
Chapter 19: The Gastrointestinal Tract
n n n n
Chapter 20: The Liver and Biliary System
n n n n n n
Chapter 21: The Pancreas
n n n
Chapter 22: The Kidney
n n n
Chapter 23: The Lower Urinary Tract and Male Reproductive System
n n n n n n n n n
Chapter 24: The Female Reproductive System and Peritoneum
n n n n n n n
Chapter 25: The Breast
n n n
Chapter 26: Hematopathology
n n
Chapter 27: The Endocrine System
n n n n
Chapter 28: The Skin
n n n
Chapter 29: The Head and Neck
n n n n n
Chapter 30: Bones, Joints and Soft Tissue
n n n n n n
Chapter 31: Skeletal Muscle and Peripheral Nervous System
n n n n n n n
Chapter 32: The Central Nervous System
n n n n n
Chapter 33: The Eye
n n n
Chapter 34: Forensic Pathology
n n n
,Rubin's Pathology: Clinicopathologic Foundations of
n n n n
MedicineChapter 1: Cell Adaptation, Injury and Death
n n n n n n n
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
n n n n n n n n n n n n n
1. of:
A) release of stored calcium from the mitochondria.n n n n n n
B) improved intracellular volume regulation. n n n
C) decreased influx across the cell membrane. n n n n n
D) attraction of calcium to fatty infiltrates. n n n n n
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
n n n n n n n n n n n n n n n n n
2. Adaptation to the reduced size of the liver leads to _
n ofthe remaining liver cells.
n n n n n n n n n n n n n
A) metaplasia
B) organ atrophy n
C) compensatory hyperplasia n
D) physiologic hypertrophy n
A person eating peanuts starts choking and collapses. His airway obstruction is partially cleared,
n n n n n n n n n n n n n
but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
n n n n n n n n n n n n n
3. caused a cerebral infarction and resulting
n n _ in the brain. n n n n n n
A) caspase activation n
B) coagulation necrosis n
C) rapid phagocytosis n
D) protein p53 deficiency n n
Bacteria and viruses cause cell damage by
n n n n n n , which is unique from the intracellular
n n n n n n
4. damage caused by other injurious agents.
n n n n n
A) disrupting the sodium/potassium ATPase pump n n n n
B) interrupting oxidative metabolism processes n n n
C) replicating and producing continued injury n n n n
D) decreasing protein synthesis and function n n n n
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
n n n n n n n n n n n n n n
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
n n n n n n n n n n n n n
A) destroying phospholipids in the cell membrane. n n n n n
B) altering the immune response of the cell. n n n n n n
C) disrupting calcium storage in the cell. n n n n n
D) inactivation of enzymes and mitochondria. n n n n
, 6. Injured cells have impaired flow of substances through the cell membrane as a result of:
n n n n n n n n n n n n n n
A) increased fat load. n n
B) altered permeability. n
C) altered glucose utilization. n n
D) increased surface receptors. n n
7. Reversible adaptive intracellular responses are initiated by:
n n n n n n
A) stimulus overload. n
B) genetic mutations. n
C) chemical messengers. n
D) mitochondrial DNA. n
8. Injured cells become very swollen as a result of:
n n n n n n n n
A) increased cell protein synthesis. n n n
B) altered cell volume regulation. n n n
C) passive entry of potassium into the cell. n n n n n n
D) bleb formation in the plasma membrane.
n n n n n
A diabetic patient has impaired sensation, circulation, and oxygenation of his feet. He steps on a
n n n n n n n n n n n n n n n
piece of glass, the wound does not heal, and the area tissue becomes necrotic. The necrotic
n n n n n n n n n n n n n n n n
9. cell death is characterized by:
n n n n
A) rapid apoptosis. n
B) cellular rupture. n
C) shrinkage and collapse. n n
D) chronic inflammation. n
A 99-year-old woman has experienced the decline of cell function associated with age. A
n n n n n n n n n n n n n
10. group of theories of cellular aging focus on programmed:
n n n n n n n n
A) changes with genetic influences. n n n
B) elimination of cell receptor sites. n n n n
C) insufficient telomerase enzyme. n n
D) DNA mutation or faulty repair.
n n n n
An 89-year-old female patient has experienced significant decreases in her mobility and stamina
n n n n n n n n n n n n
during a 3-week hospital stay for the treatment of a femoral head fracture. Which of the following
n n n n n n n n n n n n n n n n n
phenomena most likely accounts for the patients decrease in muscle function
n n n n n n n n n n n
11. that underlies her reduced mobility?
n n n n
A) Impaired muscle cell metabolism resulting from metaplasia n n n n n n
B) Dysplasia as a consequence of inflammation during bone remodeling n n n n n n n n
C) Disuse atrophy of muscle cells during a prolonged period of immobility
n n n n n n n n n n
RUBIN'SPATHOLOGY:CLINICOPATHOLOGICFOUNDATIONSOF MEDICINE
n n n n n
7TH EDITION
n n
DAVIDS. STRAYER, EMANUELRUBIN
n n n n
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
n n n n n n n n n
Table of Contents:
n n
Chapter 1: Cell Adaptation, Injury and Death
n n n n n n
Chapter 2: Inflammation
n n
Chapter 3: Repair, Regeneration and Fibrosis
n n n n n
Chapter 4: Immunopathology
n n
Chapter 5: Neoplasia
n n
Chapter 6: Developmental and Genetic Diseases
n n n n n
Chapter 7: Hemodynamic Disorders
n n n
Chapter 8: Environmental and Nutritional Pathology
n n n n n
Chapter 9: Infectious and Parasitic Diseases
n n n n n
Section II: Pathogenesis of Systemic Conditions Expandable section
n n n n n n n
Chapter 10: Aging
n n
Chapter 11: Systemic Autoimmune Diseases
n n n n
Chapter 12: Sepsis
n n
Chapter 13: Obesity and Diabetes Mellitus
n n n n n
Chapter 14: The Pathology of Pregnancy
n n n n n
Chapter 15: The Amyloidoses
n n n
Section III: Diseases of Individual Organ SystemsExpandable section
n n n n n n n
Chapter 16: Blood Vessels
n n n
Chapter 17: The Heart
n n n
Chapter 18: The Respiratory System
n n n n
Chapter 19: The Gastrointestinal Tract
n n n n
Chapter 20: The Liver and Biliary System
n n n n n n
Chapter 21: The Pancreas
n n n
Chapter 22: The Kidney
n n n
Chapter 23: The Lower Urinary Tract and Male Reproductive System
n n n n n n n n n
Chapter 24: The Female Reproductive System and Peritoneum
n n n n n n n
Chapter 25: The Breast
n n n
Chapter 26: Hematopathology
n n
Chapter 27: The Endocrine System
n n n n
Chapter 28: The Skin
n n n
Chapter 29: The Head and Neck
n n n n n
Chapter 30: Bones, Joints and Soft Tissue
n n n n n n
Chapter 31: Skeletal Muscle and Peripheral Nervous System
n n n n n n n
Chapter 32: The Central Nervous System
n n n n n
Chapter 33: The Eye
n n n
Chapter 34: Forensic Pathology
n n n
,Rubin's Pathology: Clinicopathologic Foundations of
n n n n
MedicineChapter 1: Cell Adaptation, Injury and Death
n n n n n n n
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
n n n n n n n n n n n n n
1. of:
A) release of stored calcium from the mitochondria.n n n n n n
B) improved intracellular volume regulation. n n n
C) decreased influx across the cell membrane. n n n n n
D) attraction of calcium to fatty infiltrates. n n n n n
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
n n n n n n n n n n n n n n n n n
2. Adaptation to the reduced size of the liver leads to _
n ofthe remaining liver cells.
n n n n n n n n n n n n n
A) metaplasia
B) organ atrophy n
C) compensatory hyperplasia n
D) physiologic hypertrophy n
A person eating peanuts starts choking and collapses. His airway obstruction is partially cleared,
n n n n n n n n n n n n n
but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
n n n n n n n n n n n n n
3. caused a cerebral infarction and resulting
n n _ in the brain. n n n n n n
A) caspase activation n
B) coagulation necrosis n
C) rapid phagocytosis n
D) protein p53 deficiency n n
Bacteria and viruses cause cell damage by
n n n n n n , which is unique from the intracellular
n n n n n n
4. damage caused by other injurious agents.
n n n n n
A) disrupting the sodium/potassium ATPase pump n n n n
B) interrupting oxidative metabolism processes n n n
C) replicating and producing continued injury n n n n
D) decreasing protein synthesis and function n n n n
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
n n n n n n n n n n n n n n
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
n n n n n n n n n n n n n
A) destroying phospholipids in the cell membrane. n n n n n
B) altering the immune response of the cell. n n n n n n
C) disrupting calcium storage in the cell. n n n n n
D) inactivation of enzymes and mitochondria. n n n n
, 6. Injured cells have impaired flow of substances through the cell membrane as a result of:
n n n n n n n n n n n n n n
A) increased fat load. n n
B) altered permeability. n
C) altered glucose utilization. n n
D) increased surface receptors. n n
7. Reversible adaptive intracellular responses are initiated by:
n n n n n n
A) stimulus overload. n
B) genetic mutations. n
C) chemical messengers. n
D) mitochondrial DNA. n
8. Injured cells become very swollen as a result of:
n n n n n n n n
A) increased cell protein synthesis. n n n
B) altered cell volume regulation. n n n
C) passive entry of potassium into the cell. n n n n n n
D) bleb formation in the plasma membrane.
n n n n n
A diabetic patient has impaired sensation, circulation, and oxygenation of his feet. He steps on a
n n n n n n n n n n n n n n n
piece of glass, the wound does not heal, and the area tissue becomes necrotic. The necrotic
n n n n n n n n n n n n n n n n
9. cell death is characterized by:
n n n n
A) rapid apoptosis. n
B) cellular rupture. n
C) shrinkage and collapse. n n
D) chronic inflammation. n
A 99-year-old woman has experienced the decline of cell function associated with age. A
n n n n n n n n n n n n n
10. group of theories of cellular aging focus on programmed:
n n n n n n n n
A) changes with genetic influences. n n n
B) elimination of cell receptor sites. n n n n
C) insufficient telomerase enzyme. n n
D) DNA mutation or faulty repair.
n n n n
An 89-year-old female patient has experienced significant decreases in her mobility and stamina
n n n n n n n n n n n n
during a 3-week hospital stay for the treatment of a femoral head fracture. Which of the following
n n n n n n n n n n n n n n n n n
phenomena most likely accounts for the patients decrease in muscle function
n n n n n n n n n n n
11. that underlies her reduced mobility?
n n n n
A) Impaired muscle cell metabolism resulting from metaplasia n n n n n n
B) Dysplasia as a consequence of inflammation during bone remodeling n n n n n n n n
C) Disuse atrophy of muscle cells during a prolonged period of immobility
n n n n n n n n n n
